Daniel N Holena, MD MCSE

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Assistant Professor of Surgery at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia
Department: Surgery
Graduate Group Affiliations

Contact information
Division of Trauma, Surgical Critical Care & Emergency Surgery
Penn Presbyterian Medical Center
51 North 39th St., Suite 120
Philadelphia, PA 19104
Office: 215-662-7323
Fax: 215-243-3221
McGill University, Montreal , 1995.
State University of New York at Stony Brook , 2002.
University of Pennsylvania Center for Clinical Epidemiology and Biostatistics, 2011.
MSCE (Epidemiology)
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, 2015.
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Description of Clinical Expertise

Dr. Daniel Holena is board certified in General Surgery and Surgical Critical Care. He received his General Surgery training at Cornell, and completed is fellowship in Trauma Surgery and Surgical Critical Care at the University of Pennsylvania. Dr. Holena specializes in the treatment of traumatic injury, emergency general surgery conditions, and surgical critical care. His research interests include outcomes after emergency general surgery and triage biomarkers in acute trauma.

Description of Research Expertise

Dr. Holena's research interests encompass the study of quality of care after injury. He has a specific interest in the methodology used for risk-adjusting trauma morbidity, mortality, and failure to rescue.

Selected Publications

Marcaccio C, Dumas RP, Huang Y, Wang GJ, Holena DN: Delayed endovascular aortic repair is associated with reduced in-hospital mortality in patients with blunt thoracic aortic injury. Journal of Vascular Surgery Feb. 13 2018 Notes: doi: 10.1016/j.jvs.2017.10.084.

Chreiman KM, Dumas RP, Seamon MJ, Kim PK, Reilly PM, Kaplan LJ, Christie JD, Holena DN: The IOs have it: A prospective observational study of vascular access success rates in patients in extremis using video review. Journal of Trauma & Acute Care Surgery Jan. 4 2018 Notes: doi: 10.1097/TA.0000000000001795.

Sangal R, Holena D: Man in motor vehicle collision. Journal of Emergency Medicine Jan. 5 2018 Notes: [Case Report] doi: 10.1016/j.jemermed.2017.12.014.

Holena DN, Dumas RP, Kaufman EJ, Huang Y, Wiebe DJ, Reilly PM, Christie JD: Cardiac complications and failure to rescue after injury in a mature statewide trauma system: Identifying opportunities for improvement. ESTES 2018, Valencia, Spain May 2018.

Kaufman EJ, Jacoby SF, Richmond TS. Holena DN: A safe haven for the injured? Urban trauma care at the intersection of healthcare, law enforcement, and race. Social Science & Medicine 199: 115-122, Feb. 2018 Notes: (Epub May 18, 2017).

Bores SA, Pajerowski W, Carr BG, Holena D, Meisel ZF, Mechem CC, Band RA: The Association of Prehospital Intravenous Fluids and Mortality in Patients and Penetrating Trauma. Journal of Emergency Medicine Feb 2018.

Dumas R, Holena DN, Smith BP, Jafari D, Seamon MJ, Reilly PM, Qasim Z, Cannon JW: Resuscitative endovascular balloon occlusion of the aorta: Assessing need in an urban trauma center. Journal of Surgical Research Feb. 2018.

MacKay EJ, Stubna MD, Holena DN, Reilly PM, Seamon MJ, Smith BP, Kaplan LJ, Cannon JW: In response. Anesthesia & Analgesia 126(2): 728-729, Feb. 2018.

EJ Kaufmann, A Ertefaie, DS Small, Holena DN, MK Delgado: Comparative effectiveness of initial treatment at a trauma center vs. neurosurgery-capable non-trauma center for severe, isolated head injury Journal of American College of Surgeons Feb 2018.

Eckenrode G, Kaufman EJ, Holena DN, Branas CC, Narayan M, Winchell R: Clinical characteristics of trauma centers in the United States. 13th Annual Academic Surgical Congress, Jacksonville, FL Jan. 2018.

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Last updated: 03/23/2018
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