William T. O'Donnell, M.D., Ph.D.
William T. O'Donnell, M.D., Ph.D.
Assistant Professor of Clinical Medicine
Department: Medicine
Contact information
Division of Cardiovascular Medicine
Hospital of the University of Pennsylvania
Philadelphia, PA 19104
Hospital of the University of Pennsylvania
Philadelphia, PA 19104
Education:
B.A. (Molecular Biology)
Princeton University, 1997.
Ph.D. (Genetics and Molecular Biology)
Emory University School of Medicine, 2005.
M.D.
Emory University School of Medicine, 2005.
Permanent linkB.A. (Molecular Biology)
Princeton University, 1997.
Ph.D. (Genetics and Molecular Biology)
Emory University School of Medicine, 2005.
M.D.
Emory University School of Medicine, 2005.
Selected Publications
Gertz ZM, Raina A, O'Donnell WT, McCauley BD, Shellenberger C, Kolansky DM, Wilensky RL, Forfia PR, Herrmann HC.: Comparison of invasive and noninvasive assessment of aortic stenosis severity in the elderly. Circ Cardiovasc Interv 5(3): 406-14, June 2012.Nakamoto M, Jin P, O’Donnell WT, Warren ST: Physiological identification of human transcripts translationally regulated by a specific microRNA. Hum. Mol. Genet 14: 3813-21, 2005.
Lu R, Wang H, Liang Z, Ku L, O’Donnell WT, Li W, Warren ST, Feng Y. : The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development. Proc Natl Acad Sci U S A. 101: 15201-15206, 2004.
O'Donnell WT*, Ceman S*, Reed M, Patton S, Pohl J, Warren ST.: Phosphorylation influences the translation state of FMRP-associated polyribosomes. Hum. Mol. Genet 12: 3295-305, 2003.
O'Donnell WT, Ceman S, Warren ST.: Phosphorylation of the fragile X mental retardation protein regulates translation of its mRNA ligands. Am. J. Hum. Genet. 73: 1042, 2003.
Boss V, Strohl K, O’Donnell WT, Decker M.: Intermittent hypoxia alters gene expression in the neonatal rat brain. 33rd Society for Neuroscience Annual Meeting. 2003.
O'Donnell WT, Warren ST.: A decade of molecular studies of fragile X syndrome. Ann. Rev. Neuroscience 25: 315-38, 2002.
Brown V, Jin P, Ceman S, Darnell JC, O’Donnell WT, Tenenbaum SA, Jin X, Feng Y, Wilkinson KD, Keene JD, Darnell RB, Warren ST: Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome. Cell 107: 477-87, 2001.
O'Donnell WT, Zito K, Burbach B, Warren ST, Svoboda K. : Identification of genes differentially expressed in Fmr1 knockout mouse barrel cortex. Am. J. Hum. Genet. 69: 2324 Suppl 1, 2001.
O’Donnell WT, Warren ST.: Inverstigating the cause of macroorchidism in fragile X syndrome using oligonucleotide microarrays. Am. J. Hum.Genet. 67: 2045 Suppl. 2, 2000.