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Justin E. Bekelman, M.D.

Justin E. Bekelman, M.D.

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Assistant Professor of Radiation Oncology at the Hospital of the University of Pennsylvania
Department: Radiation Oncology

Contact information
Department of Radiation Oncology
Abramson Cancer Center
Perelman School of Medicine
University of Pennsylvania
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: (215) 662-7266
Fax: (215) 349-8975
Education:
A.B.
Princeton University, Princeton, NJ, 1995.
M.D.
Yale University School of Medicine, New Haven, CT, 2003.
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Description of Clinical Expertise

I am a radiation oncologist who specializes in the treatment of prostate cancer, bladder cancer, and testicular cancer. My particular expertise is managing the early detection and treatment of prostate cancer. Prostate cancers present and progress in different ways. While some prostate cancers pose little threat to health, others may grow aggressively. In many cases, radiotherapy or surgery can be curative. We are actively studying new ways to preserve bowel, urinary and sexual function after radiotherapy and to improve quality of life for patients after treatment. For example, to improve outcomes while minimizing the side effects of radiotherapy, we use sophisticated technologies like proton beam therapy and image-guided, intensity-modulated radiotherapy.

Description of Research Expertise

My main research interests are in assessing and improving the quality of cancer care, with a particular emphasis on screening, treatment and outcomes for men with prostate cancer. My current research is focused on the comparative effectiveness of prostate cancer treatments, including proton beam therapy, intensity-modulated radiotherapy, image-guided radiotherapy, brachytherapy, surgery and active surveillance. I am conducting several studies using linked cancer registry-administrative claims datasets to investigate the effectiveness of these therapies among older men. I am also the co-Principal Investigator of a multi-center randomized clinical trial that compares patient-reported outcomes after intensity-modulated radiation therapy (IMRT) versus proton beam therapy for prostate cancer. I also conduct research on bladder and testicular cancer. I am a close collaborator with other faculty at the Leonard Davis Institute of Health Economics (LDI), the University of Pennsylvania’s center for interdisciplinary health services research. I am active in the American Society for Radiology and Oncology (ASTRO) and the Radiation Oncology Institute (ROI), where I co-Chair the Research Committee and serve on the Executive Committee of the National Radiation Oncology Registry. The National Radiation Oncology Registry aims to harness health information technologies to improve the safety and quality of radiation therapy across cancers, starting with prostate cancer. I formerly served as Special Assistant to the Under Secretary of Defense in the US Department of Defense.

Selected Publications

Handorf EA, Bekelman JE, Hietjan DF, Mitra N: Evaluating costs with unmeasured confounding: a sensitivity analysis for the treatment effect. Annals of Applied Statistics 2013. In press.

Bekelman JE, Handorf EA, Guzzo T, Pollack CE, Christodouleas J, Resnick MJ, Swisher McClure S, Vaughn D, Ten Have T, Polsky D, Mitra N: Radical Cystectomy versus Bladder Preserving Therapy for Muscle-Invasive Urothelial Carcinoma: Examining Confounding and Misclassification Bias in Cancer Observational Comparative Effectiveness Research. Value in Health 2013. In press.

Christdouleas JP, Tang S, Susil RC, McNutt TR, Song DY, Bekelman J, Deville C, Vapiwala N, DeWeese TL, Lu HM, Both S: The impact of anterior proton beams in the setting of a prostate-rectum spacer. Medical Dosimetry 2013. Epub ahead of print.

Bekelman JE, Suneja G, Guzzo T, Pollack CE, Armstrong K, Epstein AJ : Effect of Practice Integration between Urologists and Radiation Oncologists on Prostate Cancer Treatment Patterns. Journal of Urology 2013. Epub ahead of print.

Swisher-McClure S, Mitra N, Lin A, Ahn P, Wan F, O'Malley B, Weinstein GS, Bekelman JE: Risk of Fatal Cerebrovascular Accidents after External Beam Radiation Therapy for Early Stage Glottic Larynx Cancer. Head and Neck 2013. Epub ahead of print.

Gray PJ, Paly JJ, Yeap BY, Sanda MG, Sandler HM, Michalski JM, Talcott JA, Coen JJ, Hamstra DA, Shipley WU, Hahn SM, Zietman AL, Bekelman JE*, and Efstathiou JA*: Patient-Reported Outcomes Following 3D Conformal, Intensity-Modulated or Proton Beam Radiotherapy for Localized Prostate Cancer. Cancer 119(9): 1729-35, 2013. *Denotes equal contribution.

Whaley JT, Kirk ML, Cengel KA, McDonough JE, Bekelman JE, Christodouleas JP. : Protective Effect Of Transparent Film Dressing On Proton Therapy Induced Skin Reactions Radiation Oncology 8(19), 2013.

Paly J, Efstathiou JA, Hedgire S, Chung P, O'Malley M, Shah A, Bekelman J, Harisinghani M, Shipley W, Zietman A, Beard C.: Mapping Patterns of Nodal Metastases in Seminoma: Rethinking Radiotherapy Fields. Radiotherapy and Oncology 106(1): 64-8, 2013.

Shah A, Paly JJ, Efstathiou JA*, Bekelman JE*: Physician Evaluation of Internet Health Information on Proton Therapy for Prostate Cancer. Int J Radiat Oncol Biol Phys 85(4): e173-7, 2012. *Denotes equal author contribution.

Baumann, B. C., Guzzo, T. J., He, J., Keefe, S. M., Tucker, K., Bekelman, J. E., Hwang, W. T., Vaughn, D. J., Bruce Malkowicz, S., Christodouleas, J. P.: A Novel Risk Stratification to Predict Local-Regional Failures in Urothelial Carcinoma of the Bladder After Radical Cystectomy. Int J Radiat Oncol Biol Phys 2012.

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Last updated: 05/23/2013
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