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Giovanni Ferrari, Ph.D.

Giovanni Ferrari, Ph.D.

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Research Assistant Professor of Surgery
Department: Surgery

Contact information
Children’s Hospital of Philadelphia
Abramson Research Building, Suite 702E
3615 Civic Center Blvd, Philadelphia, PA 19104-4318
Philadelphia, PA 19104
Office: 215 590 2459
Fax: 215 590 5454
Lab: 215 590 6098
Education:
M.S. (Molecular Biology)
University of Pavia, Italy & Italian National Research Council, 1999.
N/A
Institute for Advanced Study of Pavia, Italy (IUSS), 2004.
Ph.D. (Genetics & Cell Biology)
University of Pavia, Italy & Italian National Research Council, 2004.
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Description of Other Expertise

External Collaborations:

- The Valley Hospital Foundation, Ridgewood, NJ (Dr Juan B Grau)
- U of Texas at Austin, TX (Dr Michael S Sacks)
- Dana Farber Cancer Center, Harvard U, MA (Dr John Quackenbush)
- U of Milan, Centro Cardiologico Monzino, Italy (Dr Alessandro Parolari)
- U of Pavia, Italy (Dr Alessandra Montecucco)
- New York University, NY (Dr Paolo Mignatti)

Description of Research Expertise

Cardiovascular Medicine, Aortic Valve Disease, Mitral Valve Disease, Aortic Aneurysm, Angiogenesis, Tissue Engineering, Biomaterials, Cell Biology, Molecular Biology

Dr Ferrari's Lab supports a broad range of basic and translational science research projects in order to improve diagnosis, treatment, and prevention of cardiovascular disease.

Current Full-Time Lab Members:

Emanuela Branchetti, PhD - Postdoctoral Fellow
Kathryn Driesbaugh, PhD - Postdoctoral Fellow
Eric K Lai - Research Specialist

Undergraduate and Part-Time Lab Members:

Selected Publications

Poggio, Paolo, Sainger, Rachana, Branchetti, Emanuela, Grau, Juan B, Lai, Eric K, Gorman, Robert C, Sacks, Michael S, Parolari, Alessandro, Bavaria, Joseph E, Ferrari, Giovanni: Noggin attenuates the osteogenic activation of human valve interstitial cells in aortic valve sclerosis. Cardiovascular research. Oxford University Press, 2013.

Branchetti, Emanuela, Poggio, Paolo, Sainger, Rachana, Shang, Eric, Grau, Juan B, Jackson, Benjamin M, Lai, Eric K, Parmacek, Michael S, Gorman, Robert C, Gorman, Joseph H: Oxidative stress modulates vascular smooth muscle cell phenotype via CTGF in thoracic aortic aneurysm. Cardiovascular research 100(2): 316-324, November 2013.

Branchetti, Emanuela, Sainger, Rachana, Poggio, Paolo, Grau, Juan B, Patterson-Fortin, Jeffrey, Bavaria, Joseph E, Chorny, Michael, Lai, Eric, Gorman, Robert C, Levy, Robert J, Giovanni Ferrari: Antioxidant Enzymes Reduce DNA Damage and Early Activation of Valvular Interstitial Cells in Aortic Valve Sclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) 33(2): 66-74, Feb 2013.

Ferrari, Giovanni, Terushkin, Vitaly, Wolff, Martin J, Zhang, Xiaodong, Valacca, Cristina, Poggio, Paolo, Pintucci, Giuseppe, Mignatti, Paolo: TGF-β1 Induces Endothelial Cell Apoptosis by Shifting VEGF Activation of p38MAPK from the Prosurvival p38β to Proapoptotic p38α Molecular cancer research : MCR. American Association for Cancer Research, 10(5): 605-614, 2012.

Poggio Paolo, Grau Juan B, Field Benjamin C, Sainger Rachana, Seefried William F, Rizzolio Flavio, Ferrari Giovanni: Osteopontin controls endothelial cell migration in vitro and in excised human valvular tissue from patients with calcific aortic stenosis and controls. Journal of cellular physiology 226(8): 2139-49, Aug 2011.

Grau Juan B, Poggio Paolo, Sainger Rachana, Vernick William J, Seefried William F, Branchetti Emanuela, Field Benjamin C, Bavaria Joseph E, Acker Michael A, Ferrari Giovanni: Analysis of osteopontin levels for the identification of asymptomatic patients with calcific aortic valve disease. The Annals of thoracic surgery 93(1): 79-86, Jan 2012.

Sainger Rachana, Grau Juan B, Branchetti Emanuela, Poggio Paolo, Seefried William F, Field Benjamin C, Acker Michael A, Gorman Robert C, Gorman Joseph H, Hargrove Clark W, Bavaria Joseph E, Ferrari Giovanni: Human myxomatous mitral valve prolapse: Role of bone morphogenetic protein 4 in valvular interstitial cell activation. Journal of cellular physiology Nov 2011.

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Last updated: 04/07/2014
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