Boon-Keng Kevin Teo, Ph.D.
Associate Professor of Radiation Oncology at the Hospital of the University of Pennsylvania
Radiation Oncology Protocol Review Committee, University of Pennsylvania
Radiation Oncology, Head and Neck Service Physics Support Lead, University of Pennsylvania
Proton team, Lead Physicist, University of Pennsylvania, Department Radiation Oncology
Member, Medical Physics Graduate Program Faculty Advisory Committee, University of Pennsylvania
Director of Medical Physics Division and Vice-Chair, Department of Radiation Oncology
University of Pennsylvania
Member, Faculty Senate Executive Committee, University of Pennsylvania
Department: Radiation Oncology
Contact information
Department of Radiation Oncology
Division of Medical Physics
University of Pennsylvania
3400 Civic Center Blvd
Philadelphia, PA 19104
Division of Medical Physics
University of Pennsylvania
3400 Civic Center Blvd
Philadelphia, PA 19104
Office: 215-662-6472
Email:
kevin.teo@uphs.upenn.edu
kevin.teo@uphs.upenn.edu
Publications
Education:
B.Sc (Physics)
National University of Singapore, 1996.
Ph.D. (Physics)
University of Michigan, 2002.
Permanent linkB.Sc (Physics)
National University of Singapore, 1996.
Ph.D. (Physics)
University of Michigan, 2002.
Selected Publications
Alaka BG, El H Bentefour, B-K Teo , D Samuel: A comparative study of machine-learning approaches in proton radiography using energy-resolved dose function. Phys Med 106: 102525, Feb 2023 Notes: https://dx.doi.org/10.1016/j.ejmp.2023.102525.N Yegya-Raman, C Friedes, S H Lee, M Iocolano, L Duan, X Wang, B Li, C Aggarwal, R B Cohen, W Su, A Doucette, W P Levin, K A Cengel, D DiBardino, B-K Teo , S E O'Reilly, L Sun, J D Bradley, Y Xiao, C J Langer, S J Feigenberg: Pneumonitis Rates Before and After Adoption of Immunotherapy Consolidation in Patients With Locally Advanced Non-Small Cell Lung Cancer Treated With Concurrent Chemoradiation. Int J Radiat Oncol Biol Phys 23, August 2023 Notes: https://doi.org/10.1016/j.ijrobp.2023.08.039.
H S Tan, B-K Teo , L Dong, A Friberg, C Koumenis, E Diffenderfer and JW Zou: Modeling ultra-high dose rate electron and proton FLASH effect with the physicochemical approach. Phy Med Bio 68(14): 145013, July 2023 Notes: htttps://dx.doi.org/10.1088/1361-6560/ace14d.
J Trotter, AR Pantel, B-K Teo , FE Escorcia, T Li, DA Pryma, NK Taunk: Positron Emission Tomography (PET)/Computed Tomography (CT) Imaging in Radiation Therapy Treatment Planning: A Review of PET Imaging Tracers and Methods to Incorporate PET/CT. Adv Radiat Onco 8(5): 101212, Sept 2023 Notes: https://dx.doi.org/10.1016/j.adro.2023.101212.
L Yin, W Zou, MM Kim, SM Avery, RD Wiersma, B-K Teo , L Dong, ES Diffenderfer: Evaluation of Two-voltage and Three-voltage Linear Methods for Deriving Ion Recombination Correction Factors in Proton FLASH Irradiation. IEEE Trans on Rad Plasma Med Sci 6(3): 263-270, March 2022 Notes: https://dx.doi.org/10.1109/TRPMS.2021.3078885.
W Zou, H Kim, ES Diffenderfer, DJ Carlson, CJ Koch, Y Xiao, B-K Teo , MM Kim, JM Metz, Y Fan, A Maity, C Koumenis, TM Busch, R Wiersma, KA Cengel, L Dong: A phenomenological model of proton FLASH oxygen depletion effects depending on tissue vasculature and oxygen supply. Front Oncol 12: 1004121, Nov 2022 Notes: https://dx.doi.org/10.3389/fonc.2022.1004121.
W Su, CM Wright, DY Lee, M Kim, EJ Anstadt, B-K Teo , DJ Carlson, JN Lukens, A Eisbruch, A Lin: Stricter Postoperative Oropharyngeal Cancer Radiation Therapy Normal Tissue Dose Constraints Are Feasible. Pract Radiat Oncol 2022 Notes: https://doi.org/10.1016/j.prro.2022.03.006.
C Wright, J Baron, D Lee, M Kim, A Barsky, B-K Teo , J Lukens, S Swisher-McClure , A Lin: Dosimetric Results for Adjuvant Proton Radiation Therapy of HPV-Associated Oropharynx Cancer. Int J Part Ther 8(4): 47-54, 2022 Notes: https://doi.org/10.14338/ijpt-d-21-00018.
W Zou, ES Diffenderfer, KA Cengel, MM Kim, S Avery, J Konzer, Y Cai, P Boisseu, K Ota, L Yin, R Wiersma, DJ Carlson, Y Fan, TM Busch, C Koumenis, A Lin, JM Metz, B-K Teo , L Dong: Current delivery limitations of proton PBS for FLASH. Radiother Oncol 155: 212-218, February 2021 Notes: https://doi.org/10.1016/j.radonc.2020.11.002.
W Zou, ES Diffenderfer, K Ota, P Boisseau, MM Kim, Y Cai, SM Avery, DJ Carlson, RD Wiersma, A Lin, C Koumenis, KA Cengel, JM Metz, L Dong, B-K Teo : Characterization of a high-resolution 2D transmission ion chamber for independent validation of proton pencil beam scanning of conventional and FLASH dose delivery. Med Phys 48(7): 3948-3957, April 2021 Notes: http://dx.doi.org/10.1002/mp.14882.
A Kassaee, C Cheng, L Yin, W Zou, T Li, A Lin, S Swisher-McClure, JN Lukens , RA Lustig, S O'Reilly, L Dong, R Hytonen, B-K Teo : Dual-Energy Computed Tomography Proton-Dose Calculation with Scripting and Modified Hounsfield Units. Int J Part Ther 8(1): 62-72, June 2021 Notes: https://doi.org/10.14338/IJPT-20-00075.1.
SC Clasen, H Shou, G Freedman, JP Plastaras, NK Taunk, B-K Teo , AM Smith, BG Demissei, B Ky: Early cardiac effects of contemporary radiation therapy in breast cancer patients. Int J Radiat Oncol Biol Phys 109(5): 1301-1310, April 2021 Notes: https://doi.org/10.1016/j.ijrobp.2020.12.008.
H Paganetti, CJ Beltran, S Both, L Dong, JB Flanz, KM Furutani, C Grassberger, DR Grosshans, A Knopf, JA Langendijk, H Nyström, K Parodi, BW Raaymakers, C Richter, GO Sawakuchi, JM Schippers, SF Shaitelman, K Teo , J Unkelbach, P Wohlfahrt, AJ Lomax: Roadmap: proton therapy physics and biology. Phys Med Biol 66: 05RM01, Feb 2021 Notes: https://doi.org/10.1088/1361-6560/abcd16.
ES Diffenderfer, II Verginadis, MM Kim, K Shoniyozov, A Velalopoulou, D Goia, M Putt, S Hagan, S Avery, B-K Teo , W Zou, A Lin, S Swisher-McClure, C Koch, AR Kennedy, A Minn, A Maity, TM Busch, L Dong, C Koumenis, J Metz, KA Cengel: Design, Implementation, and in Vivo Validation of a Novel Proton FLASH Radiation Therapy System. Int J Radiat Oncol Biol Phys 106(2): 440-448, Feb 2020 Notes: https://doi.org/10.1016/j.ijrobp.2019.10.049.
C Hague, M Aznar, L Dong, A Fotouhi-Ghiam, LW Lee, T Li, A Lin, M Lowe, JN Lukens, A McPartlin, S O'Reilly, N Slevin, S Swisher-McClure , D Thomson, M Van Herk, C West, W Zou, B-K Teo : Inter-Fraction Robustness of Intensity-Modulated Proton Therapy in the Post-Operative Treatment of Oropharyngeal and Oral Cavity Squamous Cell Carcinomas. Br J Radiol 93(1107): 20190638, Mar 2020 Notes: https://doi.org/10.1259/bjr.20190638.
S O'Reilly, V Jain, Q Huang, C Cheng, B-K Teo , L Yin, M Zhang, E Diffenderfer, T Li, W Levin, Y Xiao, L Dong, D Feigenberg, AT Berman, W Zou: Dose to Highly Functional Ventilation Zones Improves Prediction of Radiation Pneumonitis for Proton and Photon Lung Cancer Radiation Therapy. Int J Radiat Oncol Biol Phys 107(1): 79-87, May 2020 Notes: https://doi.org/10.1016/j.ijrobp.2020.01.014.
I Malajovich, S Anamalayil, O V Dolney, B-K Teo, W T Arscott, N K Taunk: Techniques for and Uncertainties of MRI-based Reconstruction of Titanium Tandem and Ring Brachytherapy Applicators. Brachytherapy 19(5): 651-658, 2020 Notes: https://doi.org/10.1016/j.brachy.2020.05.005.
WB Harris, W Zou, C Cheng, V Jain, B-K Teo, L Dong, SJ Feigenberg, AT Berman, WP Levin, KA Cengel, SE O"Reilly: Higher Dose Volumes May Be Better for Evaluating Radiation Pneumonitis in Lung Proton Therapy Patients Compared With Traditional Photon-Based Dose Constraints. Adv Rad Onc 5(5): 943-950, 2020 Notes: https://doi.org/10.1016/j.adro.2020.06.023.
BG Alaka, EH Bentefour, C Chirvase, D Samuel, B-K Teo: Feasibility of energy-resolved dose imaging technique in pencil beam scanning mode. Biomed Phys Eng Express 6: 065009, September 2020 Notes: https://doi.org/10.1088/2057-1976/abb4ed.
Y Xie, J Petzoldt, G Janssens, F O'Grady, L Yin, EH Bentefour, J Smeets, D Prieels, RA Lustig, A Lin, B-K Teo : Prompt gamma imaging for the identification of regional proton range deviations due to anatomic change in a heterogeneous region. Br J Radiol 93(1116): 20190619, 2020 Notes: https://doi.org/10.1259/bjr.20190619.
SW Yoon, NK Taunk, GM Freedman, E Hubley, S O'Reilly, B-K Teo , S Anamalayil , L Dong, C Kennedy, W Zou, JM Metz, T Li: Per-fraction positional and dosimetric performance of prone breast tangential radiotherapy on Halcyon™ linear accelerator assessed with daily rapid kilo-voltage cone beam computed tomography: a single-institution pilot study. Radiat Oncol 7(15): 258, Nov 2020 Notes: https://doi.org/10.1186/s13014-020-01700-6.