faculty photo

A.G. Christina Bergqvist, M.D.

Associate Professor of Neurology at the Children's Hospital of Philadelphia
Attending Pediatrician, The Children's Hospital of Philadelphia
Director Ketogenic Diet Program-Division of Neurology, The Children's Hospital of Philadelphia
Consultant Neurologist, Department of Newborn Pediatrics-Neonatology, Pennsylvania Hospital, Philadelphia PA
Consultant, The Hospital of the University of Pennsylvania, Philadelphia PA
Department: Neurology

Contact information
Division of Neurology
The Children’s Hospital of Philadelphia
Colket Translational Research Building
Suite 10026
3501 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-590-1719
Fax: 215-590-1771
Stockholm’s University, Stockholm SE, 1983.
B.S. (Chemistry)
Gannon University-Cum Laude, Erie PA, 1986.
M.D. (Medicine)
Temple University School of Medicine, Philadelphia PA, 1992.
Post-Graduate Training
Intern in Pediatrics, St Christopher's Hospital for Children/ Temple University School of Medicine, Philadelphia PA, 1992-1993.
Resident in Pediatrics, St Christopher’s Hospital for Children/ Temple University School of Medicine, Philadelphia PA, 1993-1994.
Child Neurology Resident, The Children’s Hospital of Philadelphia/ University of Pennsylvania, Philadelphia PA, 1994-1997.
Fellowship in Clinical Neuro-Physiology, EEG and Epilepsy, The Children’s Hospital of Philadelphia, Philadelphia PA, 1997-1999.
National Board of Medical Examiners American Academy of Neurology and Psychiatry with specialization in Child Neurology , 1999.
Maintenance of Certification in Child Neurology, 2010.
American Board of Psychiatry and Neurology, Certification in Epilepsy, 2013.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Description of Research Expertise

Selected Publications

Research Publications, peer reviewed.

1. Bergqvist AGC, Goldberg H, Thorarensen O, Bird S. Posterior cervical spinal cord infarction following vertebral artery dissection. Neurology,48(8):1112-1115, 1997.

2. Bergqvist AGC. Side Effects of Epilepsy. Epilepsy Quarterly, 6(1):4, 11-12, 1998.

3. Bergqvist AGC, Chee CM, Lutchka L and Brooks-Kayal A. Successful Treatment of Acquired Epileptic Aphasia with the Ketogenic Diet. J Child Neurol, 14(11):696-701,1999.

4. Telfeian EA, Bergqvist AGC, Danielak C, Simon SL, Duhaime A. Recovery of Language after left hemispherectomy in a sixteen year old girl with late onset seizures. Pediatr Neurosurg, 37(1):19-21, 2002.

5. Bergqvist AGC, Chee CM, Lutchka L, Rychik J, Stallings VA. Selenium Deficiency Associated with Cardiomyopathy: A complication of the Ketogenic Diet. Epilepsia,44(4):618-620, 2003.

6. Wang ZJ, Bergqvist AGC, Hunter JV, et al. In vivo Measurement of Brain Metabolites Using Two-Dimensional Double-Quantum MR SpectroscopyExploration of GABA Levels in a Ketogenic Diet. Mag Reson Med, 49(4):615-619, 2003.

7. Farina L, Bergqvist AGC, Zimmerman RA, Haselgrove J, Hunter JV, Bilaniuk LT. Acute diffusion abnormalities in the hippocampus of children with new-onset of seizures: the development of mesial temporal sclerosis.
Neuroradiology, 46(4):251-257, 2004.

8. Bergqvist AGC, Schall JI, Gallagher PR, Cnaan A and Stallings V. Gradual versus fasting introduction of the ketogenic diet: A prospective randomized clinical trial of efficacy. Epilepsia, 46(11)1810-1819, 2005.

9. Bergqvist AGC, Schall JI, Stallings VA. Vitamin D status in children with intractable epilepsy, and impact of the ketogenic diet. Epilepsia, 48(1):66-71,2007.

10. Kossoff EH, Pyzik PL, Rubenstein JE, Bergqvist AGC, Buchhalter JR, Donner EJ, Nordli DR, Wheless JW. Combined ketogenic diet and vagus nerve stimulation: rational polytherapy? Epilepsia, 48(1):77-81, 2007.

11. Bergqvist AGC, Schall JI, Richard EL, Gallagher PR, Stallings VA. Predictive power of first morning glucose and the ketogenic diet. Neuropediatrics,38:193-196, 2007.

12. Kilaru S, Bergqvist AGC. Current Treatment of myoclonic astatic epilepsy: Clinical experience at the Children’s Hospital of Philadelphia. Epilepsia,48(9):1-5, 2007.

13. Volpe S, Schall JI, Stallings VA, Gallagher MA, Stallings VA, Bergqvist AGC.Nutrient intake of children with intractable epilepsy compared to healthy children. J Am Diet Assoc, 107:1014-1018, June 2007.

14. Bergqvist AGC, Schall JI, Trabulsi J, Stallings VA. Growth failure in children with intractable epilepsy is not due to increased resting energy expenditure.Dev Med & Child Neuro, 50:439-444, April 2008.

15. Caspari SS, Bergqvist AGC, Kotegal S, Strand EA. Obstructive sleep apnea, seizures,and childhood apraxia of speech. Peds Neurology,38:422-425, March 2008.

16. Bergqvist AGC, Schall AI, Stallings VA, Zemel BS. Progressive bone mineral content loss in children with intractable epilepsy treated with the ketogenic diet. Am J Clin Nutr, 88:1678-1684

Research Publications, peer-reviewed reviews:

1. Bergqvist AGC. Idiopathic Pediatric Epilepsy Syndromes. Continuum/Epilepsy,13(4):106-120, August 2007.

2. Kossoff EH, Zupec-Kania BA, Amark PE, Ballaban-Gil KR, Bergqvist AGC, Blackford R, Buchhalter JR, Caraballo RH, Cross JH, Dahlin MD, Donner EJ, Klepper J, Jehle RS, Kim HD, Liu YMC, Nation J, Nordli DR, Pfeifer HH, Rho JM, Stafstrom CE, Thiele EA, Turner Z, Wirrell EC, Wheless JW, Veggiotti P, Vining EPG, and The Charlie Foundation, and the Practice Committee of the Child Neurology Society (2008) Optimal clinical management of children receiving the ketogenic diet: Recommendations of the International Ketogenic Diet Study Group. Epilepsia Published Online: 25-Sept-2008; doi: 10.1111/j.1528-1167.2008.01765.x

Selected Publications

Zaman T, Helig I, Bozovic IB, DeBrosse S, Bergqvist AC, Medne L, Maver A, Helbig KL, Zang Xiahong, Goldberg EM.: "Mutations in SCN3A cause early infantile epileptic encephalopathy" Annals of Neurology 83(4): 703-717, April 2018.

Carolien G. F. de Kovel, PhD1,2; Steffen Syrbe, MD, PhD3; Eva H. Brilstra, MD, PhD1; Nienke Verbeek, MD, PhD1; Bronwyn Kerr, PhD4,5,6; Holly Dubbs, MD7; Allan Bayat, MD, PhD8; Sonal Desai, MGC, CGC9; Sakkubai Naidu, MD10,11; Siddharth Srivastava, MD12; Hande Cagaylan, MD13; Uluc Yis, MD, PhD14; Carol Saunders, PhD15,16,17; Martin Rook, PhD18; Susanna Plugge, MSc19; Hiltrud Muhle, MD20; Zaid Afawi, MD, PhD21; Karl-Martin Klein, MD, PhD22; Vijayakumar Jayaraman, MSc23; Ramakrishnan Rajagopalan, PhD23; Ethan Goldberg, MD, PhD7; Eric Marsh, MD, PhD7; Sudha Kessler, MD, MSCE7; Christina Bergqvist, MD7; Laura K. Conlin, PhD23; Bryan L. Krok, PhD23; Isabelle Thiffault, PhD15,16; Manuela Pendziwiat, MSc20; Ingo Helbig, MD7,24; Tilman Polster, MD, PhD25; Ingo Borggraefe, MD, PhD26; Johannes R. Lemke, MD, PhD27; Marie-José van den Boogaardt, MD, PhD1; Rikke S. Møller, MSc, PhD8,28; Bobby P. C. Koeleman, PhD1: "Neurodevelopmental Disorders Caused by De Novo Variants in KCNB1 Genotypes and Phenotypes" JAMA Neurol 74(10): 1228-1236, October 2017.

Masnada, Silvia; Hedrich, Ulrike BS; Gardella, Elena; Schubert, Julian; Kaiwar, Charu; Klee, Eric W; Lanpher, Brendan C; Gavrilova, Ralitza H; Synofzik, Matthis; Bast, Thomas; Gorman, Kathleen; King, Mary D; Allen, Nicholas M; Conroy, Judith; Zeev, Bruria Ben; Tzadok, Michal; Korff, Christian; Dubois, Fanny; Ramsey, Keri; Narayanan, Vinodh; Serratosa, Jose M; Giraldez, Beatriz G; Helbig, Ingo; Marsh, Eric; O'Brian Margaret; Bergqvist, Christina A; Binelli, Adrian; Porter, Brenda; Caglayan, Hande S; Arslan, Muluay; Pena, Sergio D.J; Sisodiya, Sanjay M; Balestrini, Simona; Syrbe, Steffen; Veggiotti, Pierangelo; Lemke, Johannes R; Moller, Rikke S; Lerche, Holger and Guido Rubboli: "Clinical spectrum and genotype-phenotype associations of KCNA2-related encephalopathies" Brain. Oxford University Press, 140(9): 2337-2354, September 2017.

Marsh ED, Bergqvist AGC, Medne L, Hassoun P, Gonatas NK, Eagle RC, and LB O'Rorke-Adams: "Profound hypomyelination in a case of a severe early epileptic encephalopathy due to a suspected polyol disorder" Journal of Child Neurology July 2016.

Bergqvist AGC, Fenton C, Chee C, Groveman, S, Rice C and Wardley BL: "A taste and acceptance study of a low carbohydrate, vitamin, mineral and trace element supplement for use in the Ketogenic diet utilizing a family day concept for recruitment" Journal of dietary supplements May 2016.

Groveman S, Fenton C, Randall R, Chee C, Bergqvist AGC : "Improved lipid profile with ketocal® 4:1 liquid" Infant Child & Adolescent Nutrition 7(3): 157-161, June 2015.

Fenton C, Groveman S, Chee C, AGC Bergqvist : "Use of Expressed Breast Milk with the Ketogenic Diet" Infant, Child & Adolescent Nutrition 7(6): 342-346, June 2015.

Groleau V,Schall J, Stallings V, Bergqvist AGC : "Long Term Impact of Ketogenic Diet on Growth and Resting Energy Expenditure in Children with Intractable Epilepsy" Developmental Medicine & Child Neurology 56(9): 898-904, September 2014 Notes: doi: 10.1111/dmcn.12462. [Epub ahead of print).

Li H, Jauregui J ,Fenton C, Chee C, Bergqvist AGC: "Epilepsy Treatment Simplified through Mobile Ketogenic Diet Planning" Journal of Medical Application 3(2): 11-15, July 2014.

Taub K, Kilaru-Kessler S, Bergqvist AGC: "Risk of Seizure Recurrence After Achieving Initial Seizure Freedom on the Ketogenic Diet" Epilepsia 55(4): 579-83, April 2014 Notes: published ahead on line doi: 10.1111/epi.12583. Epub 2014 Mar 27.

back to top
Last updated: 05/25/2018
The Trustees of the University of Pennsylvania

© The Trustees of the University of Pennsylvania | Site best viewed in a supported browser. | Site Design: PMACS Web Team.