Department of Neurology

Department of Neurology
faculty photo

Rebecca N. Ichord, MD

Associate Professor of Neurology at the Children's Hospital of Philadelphia
Director, Pediatric Stroke Program, Children's Hospital of Philadelphia
Department: Neurology

Contact information
Dept. of Neurology
Children’s Hospital of Philadelphia
CTRB 10th Floor
3501 Civic Ctr Blvd
Philadelphia, PA 19104-4318
Office: 215-590-4142
Fax: 215-590-5120
B.S. (Biology, Magna cum laude)
University of Hawaii , 1975.
(year 1-2), New York Medical College, 1977.
(year 3-4) George Washington University School of Medicine (with distinction), 1979.
Post-Graduate Training
Resident & Chief Resident in Pediatrics, Children’s National Medical Center, Washington, D.C. , 1979-1983.
Clinical Fellow in Developmental Pediatrics, J.F.Kennedy Institute, Johns Hopkins Hospital, Baltimore, Md. , 1983-1985.
Resident and Chief Resident in Child Neurology, Johns Hopkins Medical Institutions, Baltimore, Md. , 1988-1991.
American Board of Pediatrics, 1984.
American Board of Psychiatry and Neurology, with expertise in Child Neurology, 1992.
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Description of Research Expertise

Clinical research is focused primarily on stroke in childhood, including arterial ischemic stroke, intracranial hemorrhage, cerebral venous thrombosis, and related cerebral vascular disorders. Current active research activities include an NIH-funded multicenter cohort study to evaluate safety/dose-finding for thrombolysis in pediatric stroke (TIPS); vascular effects of infection in pediatric stroke (VIPS); inflammatory coagulation markers in pediatric stroke; neurological manifestations of cerebral ischemic injury in sickle cell anemia (SITT and SWiTCH trials); a two-center cohort study of outcome predictors in childhood spontaneous intracranial hemorrhage; and a pilot study of treadmill training therapy in children recovering from stroke.

Related research activities through collaborations locally at CHOP/Penn and nationally include: hypothermia for pediatric cardiac arrest, and mechanisms of secondary injury in traumatic brain injury in children.

Description of Clinical Expertise

Childhood Stroke & acute brain injury due to cardiac arrest and traumatic brain injury. Primary clinical focus is stroke. As director of the CHOP Stroke Program, I oversee operation of clinical stroke care programs through a 24/7 rapid response neurovascular consultation service and multidisciplinary out-patient stroke follow-up clinic. The Stroke Program team includes expert care in neonatal stroke and cognitive effects of stroke by Dr. Lori Billinghurst, and effects of congenital heart disease on developing brain by Dr. Daniel Licht. Training elements include bedside & didactic teaching activities for physician and nursing staff within CHOP, and community outreach via a CME program for primary ED & pediatric practitioners. A pediatric stroke fellowship was established in July 2008.

Selected Publications

Lin, K. Y., Kerur, B., Witmer, C. M., Beslow, L. A., Licht, D. J., Ichord, R. N., Kaufman, B. D.: Thrombotic events in critically ill children with myocarditis. Cardiol Young 9: 1-8, Sept 2013.

Emmanuele V, Sotiriou E, Rios PG, Ganesh J, Ichord R, Foley AR, Akman HO, Dimauro S. : A Novel Mutation in the Mitochondrial DNA Cytochrome b Gene (MTCYB) in a Patient With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes Syndrome. J Child Neurol 28(2): 236-42 Feb 2013.

Quinn, C. T., McKinstry, R. C., Dowling, M. M., Ball, W. S., Kraut, M. A., Casella, J. F., Dlamini, N., Ichord, R. N., Jordan, L. C., Kirkham, F. J., Noetzel, M. J., Roach, E. S., Strouse, J. J., Kwiatkowski, J. L., Hirtz, D., DeBaun, M. R.: Acute silent cerebral ischemic events in children with sickle cell anemia. JAMA Neurol 70(1): 58-65, 2013.

Binenbaum G, Christian CW, Ichord RN, Ying G, Simon MA, Romero K, Pollock AN, Forbes BJ: Retinal Hemorrhage and Brain Injury Patterns on Diffusion-weighted Magnetic Resonance Imaging in Injured Children. Journal of Amer Assoc Ped Ophthalmology Strabismus in press, 2013.

Beslow LA, Ichord RN, Gindville MC, Kleinman JT, Bastian RA, Smith SE, Licht DJ, Hillis AE, Jordan LC : Hematoma Expansion is Common after Spontaneous Intracerebral Hemorrhage in Children. JAMA Neurology in press, 2013.

Gaballah M, Storm PB, Rabinowitz D, Ichord R, Krishnamurthy G, Keller MS, McIntosh A, Hurst R, Cahill AM : Intra-operative Cerebral Angiography in AVM Resection in the Pediatric Population: A single institutional experience. J Neurosurg:Pediatrics in press, 2013.

Arkuszewski, M., Krejza, J., Chen, R., Ichord, R., Kwiatkowski, J. L., Bilello, M., Zimmerman, R., Ohene-Frempong, K., Melhem, E. R.: Prevalence of intracranial stenosis and silent cerebral infarcts in children with sickle cell anemia and low risk of stroke. Int J Stroke 8(7): E50-1, 2013.

Beslow, L. A., Abend, N. S., Gindville, M. C., Bastian, R. A., Licht, D. J., Smith, S. E., Hillis, A. E., Ichord, R. N., Jordan, L. C.: Pediatric intracerebral hemorrhage: acute symptomatic seizures and epilepsy. JAMA Neurol 70(4): 448-54, 2013.

Bruno, C. J., Beslow, L. A., Witmer, C. M., Vossough, A., Jordan, L. C., Zelonis, S., Licht, D. J., Ichord, R. N., Smith, S. E.: Haemorrhagic stroke in term and late preterm neonates. Arch Dis Child Fetal Neonatal Ed in press, 2013.

Kranick, S. M., Campen, C. J., Kasner, S. E., Kessler, S. K., Zimmerman, R. A., Lustig, R. A., Phillips, P. C., Beslow, L. A., Ichord, R., Fisher, M. J.: Headache as a risk factor for neurovascular events in pediatric brain tumor patients. Neurology 80(16): 1452-6, 2013.

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Last updated: 09/14/2013
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