Department of Neurology

Department of Neurology
faculty photo

Rebecca N. Ichord, MD

Associate Professor of Neurology at the Children's Hospital of Philadelphia
Director, Pediatric Stroke Program, Children's Hospital of Philadelphia
Department: Neurology

Contact information
Dept. of Neurology
Children’s Hospital of Philadelphia
CTRB 10th Floor
3501 Civic Ctr Blvd
Philadelphia, PA 19104-4318
Office: 215-590-4142
Fax: 215-590-5120
B.S. (Biology, Magna cum laude)
University of Hawaii , 1975.
(year 1-2), New York Medical College, 1977.
(year 3-4) George Washington University School of Medicine (with distinction), 1979.
Post-Graduate Training
Resident & Chief Resident in Pediatrics, Children’s National Medical Center, Washington, D.C. , 1979-1983.
Clinical Fellow in Developmental Pediatrics, J.F.Kennedy Institute, Johns Hopkins Hospital, Baltimore, Md. , 1983-1985.
Resident and Chief Resident in Child Neurology, Johns Hopkins Medical Institutions, Baltimore, Md. , 1988-1991.
American Board of Pediatrics, 1984.
American Board of Psychiatry and Neurology, with expertise in Child Neurology, 1992.
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Description of Research Expertise

Clinical research is focused primarily on stroke in childhood, including arterial ischemic stroke, intracranial hemorrhage, cerebral venous thrombosis, and related cerebral vascular disorders. Current active research activities include an NIH-funded multicenter cohort study to evaluate safety/dose-finding for thrombolysis in pediatric stroke (TIPS); vascular effects of infection in pediatric stroke (VIPS); inflammatory coagulation markers in pediatric stroke; neurological manifestations of cerebral ischemic injury in sickle cell anemia (SITT and SWiTCH trials); a two-center cohort study of outcome predictors in childhood spontaneous intracranial hemorrhage; and a pilot study of treadmill training therapy in children recovering from stroke.

Related research activities through collaborations locally at CHOP/Penn and nationally include: hypothermia for pediatric cardiac arrest, and mechanisms of secondary injury in traumatic brain injury in children.

Description of Clinical Expertise

Childhood Stroke & acute brain injury due to cardiac arrest and traumatic brain injury. Primary clinical focus is stroke. As director of the CHOP Stroke Program, I oversee operation of clinical stroke care programs through a 24/7 rapid response neurovascular consultation service and multidisciplinary out-patient stroke follow-up clinic. The Stroke Program team includes expert care in neonatal stroke and cognitive effects of stroke by Dr. Lori Billinghurst, and effects of congenital heart disease on developing brain by Dr. Daniel Licht. Training elements include bedside & didactic teaching activities for physician and nursing staff within CHOP, and community outreach via a CME program for primary ED & pediatric practitioners. A pediatric stroke fellowship was established in July 2008.

Selected Publications

Sultan SM, Beslow LA, Vossough A, Elkind MS, Kasner SE, Mirsky DM, Licht DJ, Ichord RN: Predictive validity of severity grading for cerebral steno-occlusive arteriopathy in recurrent childhood ischemic stroke. Int J Stroke Aug 2014.

Dowling MM, Noetzel MJ, Rodeghier MJ, Quinn CT, Hirtz DG, Ichord RN, Kwiatkowski JL, Roach ES, Kirkham FJ, Casella JF, DeBaun MR. : Headache and Migraine in Children with Sickle Cell Disease are Associated with Lower Hemoglobin and Higher Pain Event Rates but not Silent Cerebral Infarction. J Pediatrics 164(5): 1175-1180, May 2014.

Rhee E, Hurst R, Pukenas B, Ichord R, Cahill AM, Rossano J, Fuller S, Lin K: Mechanical embolectomy for ischemic stroke in a pediatric ventricular assist device patient. Ped Transplant 18(3): E88-92, May 2014.

Arkuszewski M, Krejza J, Chen R, Ichord R, Kwiatkowski JL, Bilello M, Zimmerman R, Ohene-Frempong K, Melhem ER: Sickle cell anemia: Intracranial stenosis and silent cerebral infarcts in children with low risk of stroke. Adv Med Sci 59(1): 108-13, Mar 2014.

Gaballah M, Storm PB, Rabinowitz D, Ichord R, Krishnamurthy G, Keller MS, McIntosh A, Hurst R, Cahill: Intra-operative Cerebral Angiography in AVM Resection in the Pediatric Population: A single institutional experience. AM J Neurosurg:Pediatrics 13(2): 222-228, Feb 2014.

King AA, Strouse JJ, Rodeghier MJ, Compas BE, Casella JF, McKinstry RC, Noetzel MJ, Quinn CT, Ichord R, Dowling MM, Miller JP, DeBaun MR: Parent education and biologic factors influence on cognition in sickle cell anemia. Am J Hematology 89(2): 162-7, Feb 2014.

Beslow LA, Ichord RN, Gindville MC, Kleinman JT, Bastian RA, Smith SE, Licht DJ, Hillis AE, Jordan LC : Hematoma Expansion is Common after Spontaneous Intracerebral Hemorrhage in Children. JAMA Neurology 71(2): 165-71, Feb 2014.

Beslow LA, Ichord RN, Gindville MC, Kleinman JT, Engelmann BA, Bastian RA, Licht DJ, Smith SE, Hillis AE, Jordan LC: The Pediatric Intracerebral Hemorrhage Score: A Simple Grading Scale for Intracerebral Hemorrhage in Children. Stroke 45(1): 66-70, Jan 2014.

Binenbaum G, Christian CW, Ichord RN, Ying G, Simon MA, Romero K, Pollock AN, Forbes BJ: Retinal Hemorrhage and Brain Injury Patterns on Diffusion-weighted Magnetic Resonance Imaging in Injured Children. Journal of Amer Assoc Ped Ophthalmology Strabismus 17(6): 603-8, Dec 2013.

Lin, K. Y., Kerur, B., Witmer, C. M., Beslow, L. A., Licht, D. J., Ichord, R. N., Kaufman, B. D.: Thrombotic events in critically ill children with myocarditis. Cardiol Young 9: 1-8, Sept 2013.

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Last updated: 08/14/2014
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