Department of Neurology

Department of Neurology
faculty photo

Dennis J. Dlugos, MD, MSCE

Professor of Neurology at the Children's Hospital of Philadelphia
Course Director, Brain and Behavior, Module 2, Perelman School of Medicine at the University of Pennsylvania
Director, Pediatric Regional Epilepsy Program, Division of Neurology, The Children's Hospital of Philadelphia
Director, Module 2, Perelman School of Medicine at the University of Pennsylvania
Department: Neurology

Contact information
Division of Neurology
The Children's Hospital of Philadelphia
34th and Civic Center Blvd
Colket Translational Research Building
10th floor, Room 10020
Philadelphia, PA 19104
Office: 215-590-1719
Fax: 215-590-2950
Education:
B.A. (Theology)
Loyola Marymount University, Los Angeles, CA, 1983.
M.D. (Medicine)
Columbia University College of Physicians & Surgeons, New York, NY, 1988.
M.S.C.E (Clinical Epidemiology)
Master’s of Science in Clinical Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA, 2002.
Post-Graduate Training
Intern in Pediatrics, National Naval Medical Center, Bethesda, MD, 1988-1989.
Resident in Pediatrics, Thomas Jefferson University & Alfred I. Dupont Institute, Philadelphia, PA & Wilmington, DE, 1993-1994.
Resident in Neurology/Child Neurology, University of Pennsylvania Medical Center & The Children’s Hospital of Philadelphia, Philadelphia , 1994-1997.
Fellow in Epilepsy and Clinical Neurophysiology, The Children’s Hospital of Philadelphia, Philadelphia, PA, 1997-1999.
Certifications
Neurology with Special Qualifications in Child Neurology, American Board of Psychiatry and Neurology, 1998.
Pediatrics (1998 - 2012), American Board of Pediatrics, 1998.
Clinical Neurophysiology with Special Qualifications in Epilepsy Monitoring, American Board of Clinical Neurophysiology, 1999.
Clinical Neurophysiology (1999-2009), American Board of Psychiatry and Neurology, 1999.
Epilepsy, American Board of Psychiatry and Neurology, 2013.
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Description of Research Expertise

Epilepsy Epidemiology
Epilepsy Genetics
Clinical Prediction Models

Description of Clinical Expertise

Pediatric Epilepsy
Epilepsy Genetics
Epilepsy Surgery
EEG
Clinical Neurophysiology

Selected Publications

Topjian A, Shults J, Sanchez S, Dlugos D, Berg R, Abend N: Early EEG Background Features Predict Outcomes in Children Resuscitated From Cardiac Arrest. Pediatric Critical Care Medicine 17: 547-555, 2016.

Glass HC, Shellhaas RA, Wusthoff CJ, Chang T, Abend N, Chu CJ, Cilio MR, Glidden DV, Bonifacio SL, Massey S, Tsuchida TN, Silverstein FS, Soul JS, and the Neonatal Seizure Registry Study Group (including Dlugos DJ): Contemporary Profile of Seizures in Neonates: A Prospective Cohort Study. Journal of Pediatrics 174: 98-103, 2016.

French JA, Lawson JA, Yapici Z, Ikeda H, Polster T, Nabbout P, Curatolo P, de Vries PJ, Dlugos DJ, Berkowitz N, Voi M, Peyrard S, Pelov D, and Franz DN : Adjunctive everolimus therapy for treatment-resistant focal-onset seizures associated with tuberous sclerosis (EXIST-3): a phase 3, randomised, double-blind, placebo-controlled study Lancet 388: 2153-63, 2016.

The Pediatric Epilepsy Research Consortium (including Dlugos DJ): Response To Second Treatment After Initial Failed Treatment In A Multicenter Prospective Infantile Spasms Cohort. Epilepsia 57: 1834-1842, 2016.

Epi4K Consortium (including Dlugos DJ): De Novo mutations in SLC1A2 and CACNA1A are important causes of epileptic encephalopathies. American Journal of Human Genetics 99: 287-298, 2016.

Knupp K, Coryell J, Nickels K, Ryan N, Leister E, Loddenkemper T, Grinspan Z, Hartman A, Kossoff E, Gaillard W, Mytinger J, Joshi S, Shellhaas R, Sullivan J, Dlugos D, Hamikawa L, Berg A, Millichap J, Nordli D, Wirrell E and the Pediatric Epilepsy Research Consortium : Response To Treatment In A Prospective National Infantile Spasms Cohort Annals of Neurology 79: 475-84, 2016.

Winawer M, Shih J, Beck E, Hunter J, Epstein M, and the EPGP Investigators (including Dlugos D): Genetic effects on sleep/wake variation of seizures. Epilepsia 57: 557-565, 2016.

Williams RP, Banwell B, Berg RA, Dlugos DJ, Donnelly M, Ichord R, Kessler S, Lavelle J, Massey S, Hewlett J, Parker A, Topjian A, Abend NS: Impact of an ICU EEG monitoring pathway on timeliness of therapeutic intervention and electrographic seizure termination. Epilepsia 75: 786-795, 2016.

Johannes R Lemke, Kirsten Geider, Katherine L Helbig, Henrike O Heyne, Hannah Schütz, Julia Hentschel, Carolina Courage, Christel Depienne, Caroline Nava, Delphine Heron, Rikke S Møller, Helle Hjalgrim, Dennis Lal, Bernd A Neubauer, Peter Nürnberg, Holger Thiele, Gerhard Kurlemann, Georgianne L Arnold, Vikas Bhambhani, Deborah Bartholdi, Christeen Ramane J Pedurupillay, Doriana Misceo, Eirik Frengen, Petter Strømme, Dennis J Dlugos, Emily S Doherty, Emilia K Bijlsma, Claudia A Ruivenkamp, Mariette J.V. Hoffer, Amy Goldstein, Deepa S Rajan, Vinodh Narayanan, Keri Ramsey, Newell Belnap, Isabelle Schrauwen, Ryan Richholt, Bobby PC Koeleman, Joaquim Sá, Carla Mendonça, Carolien G de Kovel, Sarah Weckhuysen, Katia Hardies, Peter De Jonghe, Linda De Meirleir, Mathieu Milh, Catherine Badens, Marine Lebrun, Tiffany Busa, Christine Francannet, Amélie Piton, Erik Riesch, Saskia Biskup, Heinrich Vogt, Thomas Dorn, Ingo Helbig, Jacques L Michaud, Bodo Laube, and Steffen Syrbe: Delineating the GRIN1 phenotypic spectrum – a distinct genetic NMDA receptor encephalopathy. Neurology 86: 2171-8, 2016.

Abend NS, Wagenman KL, Blake TP, Schultheis MT, Radcliffe J, Berg RA, Topjian AA, Dlugos DJ: Electrographic status epilepticus and neurobehavioral outcomes in critically ill children. Epilepsy and Behavior 49: 238-244, 2015.

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Last updated: 11/27/2016
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