Measuring hypoxia in vivo
Animal Models of human disease
Cancer physiology, proliferation
Cancer physiology, tumor vasculature
Measuring hypoxia and predicting treatment response in brain tumors
Measuring hypoxia and predicting treatment responsein cervix cancer
Measuring hypoxia and predicting treatment responsein head and neck squamous cell carcinoma
Measuring hypoxia and predicting treatment responsein carcinomatosis and sarcomatosis
Measuring hypoxia and predicting treatment responsein pleural cancers
Measuring hypoxia and predicting treatment response in soft tissue sarcomas
Mentoring junior faculty
Evans, SM: Biodegradable polymersomes for the delivery of Gemcitabine to Panc-1 cells. Journal of Pharmaceutics (on line). Hindawi Publishing Company, 2013(932797), 2013.
Koch CJ, Jenkins WT, Jenkins KW, Yang XY, Shuman AL, Pickup S, Riehl1 CR, Paudya R, Poptani H, Evans SM: Mechanisms of Blood Flow and Hypoxia Production in Rat 9L Epigastric Tumors. Tumor Microenvironment and Therapy 1(1): 1-13, Dec 2012.
Lilie L Lin, LL
James B Stubbs
Jonathan M. Sorger
Michael G. Stabin
Stephen M. Hahn
Sydney M Evans
Cameron J. Koch
Heikki Minn: Radiation Dosimetry and Biodistribution of the Hypoxia Tracer 18F-EF5 in Oncologic Patients. Cancer Biotherapy & Radiopharmaceuticals 27(7): 412-9, Sep 2012.
Marotta D, Karar J, Jenkins WT, Kumanova M, Tobias JW, Baldwin D, Hadjigeorgiou A, Alexiou P, Evans SM, Alarcon R, Maity A, Koch CJ, Koumenis C: In vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection. Cancer Research
(eds.). 71(3): 779-89, Feb 2011
Evans SM, Jenkins KW, Chen HI, Jenkins WT, Judy KD, Hwang W-T, Lustig RA, Judkins AR, Grady MS, Hahn SM, Koch CJ: The Relationship among Hypoxia, Proliferation, and Outcome in Patients with De Novo Glioblastoma: A Pilot Study. Translational Oncology 3(3): 160–9, Jun 1 2010
Koch CJ, Scheuermann JS, Divgi C, Judy KD, Kachur A, Freifelder R, Saffer J, Karp J, Stubbs JM, Hahn SM, Driesbaugh J, Smith D, Prendergast S, Evans SM: Biodistribution and dosimetry of 18F-EF5 in cancer patients with preliminary comparison of 18F-EF5 uptake versus EF5 binding in human glioblastoma. European Journal of Nuclear medicine and Molecular Imaging 37(11): 2048-59, Nov 2010.
Koch CJ, Shuman AL, Jenkins WT, Kachur AV, Karp JS, Freifelder R, Dolbier WR, Evans SM: The radiation response of cells from 9L gliosarcoma tumors is correlated with [F18]-EF5 uptake. International Journal of Radiation Biology 85(12): 1137-47, Dec 2009
Cerniglia G, Pore N, Tsai JH, Schultz S, Mick R, Regine C, Xiaoman X, Durduran T, Yodh AG, Evans SM, Koch CJ, Hahn SM, Quon H, Sehgal CM,
Lee W M-F, Maity A: Epidermal growth factor inhibition modulates the microenvironment by vascular normalization to improve chemotherapy and radiotherapy efficacy. PloS one 4(8): e6539, Aug 2009.
Komar G, Seppänen M, Eskola O, Lindholm Paula, Grönroos T, Forsback S, Sipilä H, Evans SM, Solin O, Minn H: 18F-EF5: A new PET tracer for imaging hypoxia in head and neck cancer. Journal of Nuclear Medicine 49(12): 1944-51, Dec 2008.
Evans, SM, Jenkins KW, Jenkins WT, Dilling T, Judy KD, Schrlau A, Judkins A, Hahn SM, Koch CJ: Imaging and analytical methods as applied to the evaluation of vasculature and hypoxia in human brain tumors. Radiation Research 170(6): 677-90, Dec 2008.
back to top
Last updated: 10/29/2014
The Trustees of the University of Pennsylvania