breast cancer, prostate cancer, image-guided radiation therapy, biologic agents, radiosensitizers
prostate cancer, bladder cancer, testicular cancer, image-guided radiation therapy, integrative medicine
I have specialized in the care of patients with genitourinary (GU) cancer throughout my career as an Assistant and now Associate Professor in the Department of Radiation Oncology at University of Pennsylvania. The GU service works closely with members in the Departments of Urology, Medical Oncology, Pathology, and Diagnostic Radiology and Nuclear Medicine, among others, both in the clinic and in research collaborations. We treat over 300 prostate cancer patients a year, and see many more in consultation and in post-treatment follow-up.
My research interests have focused on biological and technological improvements in the delivery of photon- and proton-based radiation as part of the overall management of patients with prostate cancer. I am the Principal Investigator of the first 2 proton therapy trials, both for prostate cancer patients, at the University of Pennsylvania’s Roberts Proton Therapy Center. I am a Project Leader on a DOD Proton Therapy grant, and have extramural funding to help develop prognostic and predictive biomarkers for investigation of novel drugs, especially radiosensitizers, for use during external beam radiation therapy for prostate cancer. Among my research collaborations in this area is a phase I study testing everolimus in post-operative prostate patients that is actively enrolling patients, a study protocol first designed by one of my trainees and on which I am a coinvestigator.
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Last updated: 04/07/2014
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