I am a radiation oncologist who specializes in the treatment of prostate cancer, bladder cancer, and testicular cancer. My particular expertise is managing the early detection and treatment of prostate cancer. Prostate cancers present and progress in different ways. While some prostate cancers pose little threat to health, others may grow aggressively. In many cases, radiotherapy or surgery can be curative. We are actively studying new ways to preserve bowel, urinary and sexual function after radiotherapy and to improve quality of life for patients after treatment. For example, to improve outcomes while minimizing the side effects of radiotherapy, we use sophisticated technologies like proton beam therapy and image-guided, intensity-modulated radiotherapy.
My main research interests are in assessing and improving the quality of cancer care, with a particular emphasis on screening, treatment and outcomes for men with prostate cancer. My current research is focused on the comparative effectiveness of prostate cancer treatments, including proton beam therapy, intensity-modulated radiotherapy, image-guided radiotherapy, brachytherapy, surgery and active surveillance. I am conducting several studies using linked cancer registry-administrative claims datasets to investigate the effectiveness of these therapies among older men. I am also the co-Principal Investigator of a multi-center randomized clinical trial that compares patient-reported outcomes after intensity-modulated radiation therapy (IMRT) versus proton beam therapy for prostate cancer. I also conduct research on bladder and testicular cancer. I am a close collaborator with other faculty at the Leonard Davis Institute of Health Economics (LDI), the University of Pennsylvania’s center for interdisciplinary health services research. I am active in the American Society for Radiology and Oncology (ASTRO) and the Radiation Oncology Institute (ROI), where I co-Chair the Research Committee and serve on the Executive Committee of the National Radiation Oncology Registry. The National Radiation Oncology Registry aims to harness health information technologies to improve the safety and quality of radiation therapy across cancers, starting with prostate cancer. I formerly served as Special Assistant to the Under Secretary of Defense in the US Department of Defense.
Goldsmith B, Baumann BC, He J, Tucker K, Bekelman J, Deville C, Vapiwala N, Vaughn D, Keefe SM, Guzzo T, Malkowicz BS, Christodouleas JP: Occult pelvic lymph node involvement in bladder cancer: implications for definitive radiation. Int J Radiat Oncol Biol Phys 2014. In press.
DuGoff EH, Bekelman J, Stuart EA, Armstrong K, Pollack CE: Surgical quality is more than volume: The association between changing urologists and complications for patients with localized prostate cancer. Health Services Research 2014. In press.
Swisher-McClure S, Mitra N, Woo K, Smaldone M, Uzzo R, Bekelman JE: Increasing Use of Dose Escalated External Beam Radiation Therapy for Men with Non-Metastatic Prostate Cancer. Int J Radiat Oncol Biol Phys 2014. In press.
Christodouleas JP, Baumann BC, He, J, Hwang W, Tucker KN, Bekelman JE, Tangen CM, Lerner SP, Guzzo TJ, Malkowicz SB: Optimizing bladder cancer local-regional failure risk stratification after radical cystectomy using SWOG 8710. Cancer 2014. In press.
Corcoran AT, Handorf E, Canter D, Tomaszewski JJ, Bekelman JE, Kim SP, Uzzo RG, Kutikov A, Smaldone MC: Variation in performance of candidate surgical quality measures for muscle invasive bladder cancer by hospital type. BJU Int 2014. In press.
Martin JM, Handorf EA, Kutikov A, Uzzo RG, Bekelman JE, Horwitz EM, Smaldone MC: The Rise and Fall of Prostate Brachytherapy: Utilization of Brachytherapy for the Treatment of Localized Prostate Cancer in the National Cancer Database (NCDB). Cancer 2014. In press.
Swisher-McClure S, Mitra N, Lin A, Ahn P, Wan F, O'Malley B, Weinstein GS, Bekelman JE: Risk of Fatal Cerebrovascular Accidents after External Beam Radiation Therapy for Early Stage Glottic Larynx Cancer. Head and Neck 2013. In press.
Gray PJ, Paly JJ, Yeap BY, Sanda MG, Sandler HM, Michalski JM, Talcott JA, Coen JJ, Hamstra DA, Shipley WU, Hahn SM, Zietman AL, Bekelman JE*, and Efstathiou JA*: Patient-Reported Outcomes Following 3D Conformal, Intensity-Modulated or Proton Beam Radiotherapy for Localized Prostate Cancer. Cancer 119(9): 1729-35, 2013. *Denotes equal author contribution.
Bekelman JE, Epstein AJ, Emanuel EJ: Single vs Multiple Fraction Radiotherapy for Bone Metastases from Prostate Cancer. JAMA 310(14): 1501-02, Oct 2013.
Bekelman JE, Suneja G, Guzzo T, Pollack CE, Armstrong K, Epstein AJ
: Effect of Practice Integration between Urologists and Radiation Oncologists
on Prostate Cancer Treatment Patterns. Journal of Urology 190(1): 97-101, Jul 2013.
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Last updated: 03/05/2014
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