Penn Cardiovascular Institute

Penn Cardiovascular Institute Research Directory

faculty photo

Joseph H. Gorman, III, MD

Professor of Surgery
Department: Surgery

Contact information
Gorman Cardiovascular Research Group
Glenolden Research Laboratory
500 S. Ridgeway Avenue
Glenolden, PA 19036
Office: 267-350-9616
Fax: 267-350-9627
Education:
B.S.Ch.E. (Chemical Engineering and Chemistry )
(Magna Cum Laude)Newark College of Engineering, New Jersey Institute of Technology, Newark, New Jersey of Engineering, Department of Chemical Engineering and Chemistry, Newark, NJ , 1984.
B.S.Ch.E (Chemical Engineering and Chemistry)
Newark College of Engineering, Graduate School of Engineering, New Jersey Institute of Technology, Newark, New Jersey, 1985.
M.D.
University of Medicine and Dentistry of New Jersey/ Robert Wood Johnson Medical School, New Brunswick, NJ, 1991.
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Description of CVI Expertise

CVI Program Unit(s):
Myocyte Biology / Heart Failure

CVI Research Description:
The Gorman Cardiovascular Research Group is funded by several NIH grants, philanthropic grants and industrial contracts. This spring the group will be moving to a new facility in Glenolden Pennsylvania.

That facility will include:
Three large animal operating rooms, a cath lab, MRI, 3D echocardiography
capabilities as well as vastly expanded wet lab and office space.

The Group's Research interests include:
1) Pathophysiology of heart failure (HF)
2) Novel pharmacologic therapy for treating HF
3) Effect of left ventricular assist devices on ventricular remodeling and HF
4) Scientific evaluation of surgical procedures/devices in the treatment of HF
5) Cardiac Imaging: MRI & real time 3D echocardiography
6) Mitral valve physiology
7) Design of novel annuloplasty rings
8) Percutaneous valve repair/replacement
9) Anorexigen induced valve disease
10) Effect of selective ventricular pacing on HF
11) Development of material/processes to limit prosthetic valve calcification.

The Group collaborates with clinicians, cardiovascular scientists and engineers in both academia and industry to discover novel solutions to important cardiovascular disease.

Selected Publications

Ekhterae D, Hinmon R, Matsuzaki K, Noma Mio, Zhu W, Xiao RP, Gorman RC, Gorman III JH.: Infarction Induced Myocardial Apoptosis and ARC Activation. (In Press). Journal of Surgical Research 2010.

Bouma W, Noma M, Kanemoto S, Matsubara M, Leshnower BG, Hinmon R, Gorman III JH, Gorman RC: Gender-Related Resistance to Myocardial Ischemia-Reperfusion Injury is Associated with High Constitutive ARC Expression. American Journal of Physiology 298: H1510-H1517, 2010.

Ifkovits JL, Tous E, Minakawa M, Morita M, Robb JD, Koomalsingh KJ, Gorman III JH, Gorman RC, Burdick JA: Injectable Hydrogel Properties Influence Extent of Post-Infarction Left Ventricular Remodeling in an Ovine Model. Proceedings of the National Academy of Science 107: 11507-11512, 2010.

Matsubara M, Kanemoto S, Leshnower BG, Albone EF, Hinmon R, Plappert T, Gorman III JH, Gorman RC.: Single Dose GLP-1-Tf Ameliorates Myocardial Ischemia/Reperfusion Injury. Journal of Surgical Research (In Press). Journal of Surgical Research 2010.

Matsuzaki K, Morita M, Hamamoto H, Noma M, Robb JD, Gillespie MJ, Gorman III JH, Gorman RC: Annuloplasty for Ischemic Mitral Regurgitation does not Influence Long-Term Ventricular Remodeling. Annals of Thoracic Surgery 90: 788-795, 2010.

Witschey WR, Pilla JJ, Ferrari G, Koomalsingh KJ, Harris M, Hinmon R, Zsido GA, Gorman III JH, Gorman RC, Reddy R.: Spin Lattice Relaxation in a Swine Model of Late Ventricular Myocardial Infarction. (In Press). Magnetic Resonance in Medicine 2010.

Vergnat V, Jassar AS, Jackson BM, Ryan LP, Eperjesi TJ, Pouch AM, Weiss SJ, Cheung AT, Acker MA, Gorman III JH, Gorman RC.: Ischemic Mitral Regurgitation: A Quantitative Three-Dimensional Echocardiographic Analysis. [In Press] Annals of Thoracic Surgery 2010.

Jassar AS, Brinster CR, Vergnat V, Robb JD, Eperjesi TJ, Pouch AM, Weiss SJ, Cheung AT, Acker MA, Gorman III JH, Gorman RC, Jackson BM. : Quantitative Mitral Valve Modeling using Real-Time 3D-Echocardiography –Technique and Repeatability. [In Press] Annals of Thoracic Surgery 2010.

Ra J, Paulson EC, Wirtalla C, Rohrbacj J, Cooper JD, Kaiser LR, Gorman III JH, Rosato EF, Rappaport Kelz R, Spitz F, Kucharczuk JC.: Predictors of Extended Length of Stay following Esophagectomy for Cancer at a High Volume Center. (In Press). Journal of Surgery 2010.

Matsubara M, Kanemoto S, Leshnower BG, Albone EF, Hinmon R, Plappert T, Gorman III JH, Gorman RC: Single dose GLP-1-Tf ameliorates myocardial ischemia/reperfusion injury. [In-Press] Journal of Surgical Research 2010.

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Last updated: 03/17/2011
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