Penn Cardiovascular Institute

Penn Cardiovascular Institute Research Directory

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Joseph H. Gorman, III, MD

Professor of Surgery
Department: Surgery

Contact information
Gorman Cardiovascular Research Group
Glenolden Research Laboratory
500 S. Ridgeway Avenue
Glenolden, PA 19036
Office: 267-350-9616
Fax: 267-350-9627
B.S.Ch.E. (Chemical Engineering and Chemistry )
(Magna Cum Laude)Newark College of Engineering, New Jersey Institute of Technology, Newark, New Jersey of Engineering, Department of Chemical Engineering and Chemistry, Newark, NJ , 1984.
B.S.Ch.E (Chemical Engineering and Chemistry)
Newark College of Engineering, Graduate School of Engineering, New Jersey Institute of Technology, Newark, New Jersey, 1985.
University of Medicine and Dentistry of New Jersey/ Robert Wood Johnson Medical School, New Brunswick, NJ, 1991.
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Description of CVI Expertise

CVI Program Unit(s):
Myocyte Biology / Heart Failure

CVI Research Description:
The Gorman Cardiovascular Research Group is funded by several NIH grants, philanthropic grants and industrial contracts. This spring the group will be moving to a new facility in Glenolden Pennsylvania.

That facility will include:
Three large animal operating rooms, a cath lab, MRI, 3D echocardiography
capabilities as well as vastly expanded wet lab and office space.

The Group's Research interests include:
1) Pathophysiology of heart failure (HF)
2) Novel pharmacologic therapy for treating HF
3) Effect of left ventricular assist devices on ventricular remodeling and HF
4) Scientific evaluation of surgical procedures/devices in the treatment of HF
5) Cardiac Imaging: MRI & real time 3D echocardiography
6) Mitral valve physiology
7) Design of novel annuloplasty rings
8) Percutaneous valve repair/replacement
9) Anorexigen induced valve disease
10) Effect of selective ventricular pacing on HF
11) Development of material/processes to limit prosthetic valve calcification.

The Group collaborates with clinicians, cardiovascular scientists and engineers in both academia and industry to discover novel solutions to important cardiovascular disease.

Selected Publications

Khabbaz KR, Mahmood F, Shakil O, Warraich HJ, Gorman III JH, Gorman RC, Matyal R, Panzica P, Hess PE. : Real-Time Three-Dimensional Echocardiographic Dynamic Analysis of Mitral Valve Annular Geometry. Annals of Thoracic Surgery 95: 105-110, 2013.

Ikonomidis JS, Ruddy JM, Benton SM, Arroyo J, Brinsa TA, Stroud RE, Zeeshan A, Bavaria JE, Gorman III JH, Gorman RC, Spinale FG, Jones JA. : Aortic Dilatatopm woth Bicuspid Aortic Valves: Cusp Fusion Correlates to Matrix Metalloproteinases and Inhibitors. Annals of Thoracic Surgery 93: 457-464, 2012.

Mahmood F, Warraich HJ, Gorman III JH, Gorman RC, Chen TH, Panzica P, Maslow A, Khabbaz K.: Changes in Mitral Annular Geometry after Aortic Valve Replacement: A Three-Dimensional Transesophageal Echocardiographic Study. Journal of Heart Valve Disease 21: 696-701, 2012.

Jassar AS, Minakawa M, Shuto T, Robb JD, Koomalsingh KJ, Levack MM, Vergnat M, Eperjesi TJ, Jackson BM, Gorman III JH, Gorman RC.: Posterior Leaflet Augmentation in Ischemic Mitral Regurgitation Increases Leaflet Coaptation and Mobility. Annals of Thoracic Surgery 94: 1438-1445, 2012.

Robb JD, Harris MA, Minakawa M, Rodriguez E, Koomalsingh KJ, Shuto T, Dori Y, Gorman RC, Gorman III JH, Gillespie MJ. : An Ovine Model of Pulmonary Insufficiency and Right Ventricular Outflow Tract Dilatation. Journal of Heart Valve Disease. 21: 247-252, 2012.

Amini R, Eckert CE, Koomalsingh KJ, Minakawa M, Gorman III JH, Gorman RC,.: On the In-Vivo Deformation of the Mitral Valve Anterior Leaflet: Effects of Annular Geometry and Referential Configuration. Annals of Biomedical Engineering 40: 1455-1467, 2012.

Xu C, Jassar AS, Nathan DP, Eperjesi TJ, Brinster CJ, Vergnat M, Gorman RC, Gorman III JH, Jackson BM.: Augmented Mitral Valve Leaflet Area Decreases Leaflet Stress: A Finite Element Simulation. Annals of Thoracic Surgery 93: 1141-1145, 2012.

Tous E, Weber HM, Lee LH, Koomalsingh KJ, Takashi S, Kondo N, Gorman III JH, Lee D, Gorman RC, Burdick JA.: Tunable Hydrogel-Microsphere Composites that Modulate Local Inflammation and Collagen Bulking. Acta Biomaterialia 8: 3218-3227, 2012.

Siefert AW, Jimenez JH, Kommalsingh KJ, West DS, Aguel F, Shuto T, Gorman RC, Gorman III JH, Yoganathan AP.: Dynamic Assessment of Mitral Annular Force Profile in an Ovine Model. Annals of Thoracic Surgery 94: 59-65, 2012.

Witschey WRT, Zsido GA, Koomalsingh KJ, Pilla JJ, Gorman III JH, Gorman RC.: In Vivo Chronic Myocardial Infraction Characterization by Spin Locked Cardiovascular Magnetic Resonance Imaging. Journal of Cardiovascular Magnetic Resonance. 14: 37, 2012.

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Last updated: 09/29/2015
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