Steven M. Kawut, MD, MS
Associate Professor of Medicine
Department: Medicine
Graduate Group Affiliations
Contact information
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania School of Medicine
711 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104-6021
University of Pennsylvania School of Medicine
711 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104-6021
Office: 215-573-0258
Fax: 215-573-5325
Fax: 215-573-5325
Email:
kawut@mail.med.upenn.edu
kawut@mail.med.upenn.edu
Publications
Links
Search PubMed for articles
Penn Lung Center - Pulmonary, Allergy and Critical Care Division
Pulmonary Vascular Disease Research Program
Search PubMed for articles
Penn Lung Center - Pulmonary, Allergy and Critical Care Division
Pulmonary Vascular Disease Research Program
Education:
AB (Biology)
Harvard College, Cambridge, MA, 1991.
MD (Medicine)
Yale School of Medicine, New Haven, CT, 1995.
MS (Clinical Epidemiology)
University of Pennsylvania School of Medicine, Philadelphia, PA, 2004.
Permanent linkAB (Biology)
Harvard College, Cambridge, MA, 1991.
MD (Medicine)
Yale School of Medicine, New Haven, CT, 1995.
MS (Clinical Epidemiology)
University of Pennsylvania School of Medicine, Philadelphia, PA, 2004.
Description of CVI Expertise
CVI Program Unit Administrator:Pulmonary Vascular Disease
CVI Program Unit(s):
Pulmonary Vascular Disease
Cardiovascular Development / Congenital Heart Disease
Lipid / Atherosclerosis / CAD / ACS / Prevention
Myocyte Biology / Heart Failure
Channel Biology / Electrophysiology
Thrombosis / Hemostasis
CVI Research Description:
The focus of my research group is the role of the pulmonary vasculature and right ventricular function in health and disease. We lead or contribute to epidemiologic studies and clinical trials of pulmonary arterial hypertension, idiopathic pulmonary fibrosis, COPD, and lung transplantation.
Specific projects include:
1. A clinical trial of aspirin and simvastatin for pulmonary arterial hypertension (ASA-STAT).
2. The Pulmonary Vascular Complications of Liver Disease (PVCLD) Study Group, which investigates the mechanisms and outcomes of hepatopulmonary syndrome and portopulmonary hypertension.
3. Endothelial dysfunction and the right ventricle in the Multi-Ethnic Study of Atherosclerosis (MESA-RV), focused on the determinants of right ventricular function in subjects without clinical cardiovascular disease.
4. Endothelial dysfunction, bio-markers, and lung function in the Multi-Ethnic Study of Atherosclerosis (MESA-Lung), focused on the relationship of lung function with cardiovascular and peripheral vascular function.
5. The Lung Transplant Outcomes Group, which is examining the role of pulmonary vascular dysfunction in primary graft dysfunction.
Selected Publications
(LTOG) Lung Transplant Outcomes Group. Secondary pulmonary hypertension is a risk factor for primary graft dysfunction following lung transplantation for idiopathic pulmonary fibrosis. Poster International Society of Heart and Lung Transplantation Annual Meeting April 2008.Al-Naamani N., Maarouf O.H., Wilt J.S., D'Ovidio F., Sonett J.R., Arcasoy S., Nickolas T.L., Lederer D.J., Kawut S.M. : The Modification of Diet in Renal Disease (MDRD) formula predicts kidney failure after lung transplantation. International Society of Heart and Lung Transplantation Annual Meeting, Oral presentation) April 2008.
Tavares de Melo R.F., Lukose T.S., Bae S., Kubin C.J., Lederer D.J., Arcasoy S.M., Wilt J.S., Sonett J.R., D'Ovidio F., Kawut S.M. : The effect of CMV-immune globulin on outcomes in CMV-mismatched lung transplant recipients. Poster International Society of Heart and Lung Transplantation Annual Meeting April 2008.
(LTOG) Lung Transplant Outcomes Group, Clinical risk factors for the development of primary graft dysfunction. (Oral presentation). International Society of Heart and Lung Transplantation Annual Meeting April 2008.
Kawut S.M., Lederer D.J., Keshavjee S., Wilt J.S., Daly T., D'Ovidio F., Sonett J.R., Arcasoy S.M., Barr M.L.: Outcomes after lung retransplantation in the modern era. American Journal of Respiratory & Critical Care Medicine 177(1): 114-120, Jan 2008.
Lederer D.J., Horn E.M., Rosenzweig E.B., Karmally W., Jahnes, M., Barst R.J., Kawut S.M. : Plasma serotonin levels are normal in pulmonary arterial hypertension. Pulm Pharmacol Ther 21(1): 112-114, 2008.
Lederer D.J., Enright P.L., Kawut S.M., Hoffman E.A., Hunninghake G.W., JIang R., Barr R.G. : Predictors of subclinical restriction on spirometry: the MESA Lung Study. Poster. American Thoracic Society International Conference 2008.
Lederer D.J., Enright P.L., Kawut S.M., Hoffman E.A., Hunninghake G.W., Jiang R., Barr R.G. : Predictors of subclinical restriction on spirometry: The MESA Lung Study. Poster American Thoracic Society International Conference. 2008.
Barr R.G., Ahmed F.S., Enright P.L., Herrington D., Hoffman E.A., Jiang R., Johnson W.C., Kawut S.M., Kronmal R., Polak J., Punjabi N.M., Doyle M., Watson K.E. : Impaired flow-mediated dilation of the brachial artery is associated with low lung function: The MESA-Lung Study. Poster American Thoracic Society International Conference 2008.
Peng T., Zamanian, R., Rybak, D., Roberts, K.E., Krowka, M.J., Benza, R.L., Badesch, D.B., Taichman, D.B., Horn, E.M., Trotter, J.F., Zacks, S., Brown, R.S., Fallon, M.B., Kawut, S.M. : Genetic variation and plasma concentrations of S100A4 in portopulmonary hypertension. Poster. American Thoracic Society International Conference 2008.
| Protocol | Title | Status |
|---|---|---|
| 807771 | A Clinical Trial of Aspirin and Simvastatin in Pulmonary Arterial Hypertension | Recruiting |
» Top