Muredach P. Reilly
Assistant Professor of Medicine
Department: Medicine
Graduate Group Affiliations
Contact information
909 Biomedical Research Building II/III
421 Curie Blvd
University of Pennsylvania Medical Center
Philadelphia, PA 19104
421 Curie Blvd
University of Pennsylvania Medical Center
Philadelphia, PA 19104
Office: (215) 573-1214
Fax: (215) 573-2094
Fax: (215) 573-2094
Publications
Links
Search PubMed for articles
Cardiovascular Division Faculty
Penn Health Profile
Institute for Translational Medicine and Therapeutics
Search PubMed for articles
Cardiovascular Division Faculty
Penn Health Profile
Institute for Translational Medicine and Therapeutics
Education
MBBCh (Medicine)
University College, Dublin, Ireland, 1988.
BS (Pharmacology)
University College Dublin, Ireland , 1990.
MSCE (Epidemiology and Biostatistics)
University of Pennsylvania, 2003.
Permanent linkMBBCh (Medicine)
University College, Dublin, Ireland, 1988.
BS (Pharmacology)
University College Dublin, Ireland , 1990.
MSCE (Epidemiology and Biostatistics)
University of Pennsylvania, 2003.
Description of CVI Expertise
CVI Program Unit(s):CVI Research Description:
Dr. Reilly has extensive training and expertise in cardiovascular medicine, preventive cardiology, clinical pharmacology, epidemiology and translational research.
His interests include (1) mechanisms of atherosclerosis in metabolic syndrome, diabetes and obesity, (2) the role on innate immunity in promoting atherosclerotic risk in metabolic syndrome, (3) the functions of adipose tissue in regulation of HDL cholesterol and reverse cholesterol transport, (4) genetics of atherosclerosis and dyslipidemia in high risk populations including type 2 diabetes, subjects with family history of CAD, populations with chronic kidney disease and in HIV infected populations, and (5) non-invasive imaging of atherosclerosis in humans.
Dr. Reilly employs a translational approach to his research including cell and animal based mechanistic studies, mechanistic patient-oriented, General Clinical Research Center studies as well as larger scale epidemiological studies in humans.
Selected Publications
Wolfe ML, Iqbal N, Gefter W, Mohler ER III, Rader DJ, Reilly MP.: Coronary artery calcification at electron beam CT is increased in asymptomatic type 2 diabetics independent of traditional risk factors. J Cardiovasc Risk. 9: 369-76, 2002.Kawashiri M, Zhang Y, Usher D, Reilly M, Pure E, Rader DJ.: Effects of coexpression of LDLR and apolipoprotein E on cholesterol metabolism and atherosclerosis in LDLR-deficient mice. J Lipid Res 42: 943-50, 2001.
Catella-Lawson F, Reilly MP, Kapoor SC, Cucchiara AJ, DeMarco S, Tournier B, Vyas SN, FitzGerald GA.: Cyclooxygenase inhibitors and the anti-platelet effect of aspirin. N Eng J Med 345: 1809-17, 2001.
Reilly MP, Wolfe ML, Picoult Newberg L, Delemos AS, Mohler ER III, Pohl M, Grant D, Gefter W, Boyce-Jacino M, Rader DR. : Interaction of the paraoxonase genes PON1 and PON2 and the methyltetrahydrofolate reductase gene and association with coronary artery calcification at electron beam CT. Am J Cardiol 88:84E, 2001.
Reilly MP, Wolf R, Mohler ER III, Wright A, Song HK, Wehrli F, Rader DJ.: Longitudinal study of lipid-modifying therapies on carotid atherosclerotic plaque morphology in vivo as assessed by magnetic resonance imaging. Am J Cardiol 88;85E, 2001.
Reilly MP, Wolfe ML, Picoult-Newberg L, Delemos AS, Mohler ER III, Grant DM, Rader DJ.: Association of ICAM-1 K469 gene polymorphism with early coronary atherosclerosis in asymptomatic Caucasian males. ; Circulation Page: 104:II-283. 2001.
Reilly MP, Mohler ER. : Cilostazol: Pharmacology and clinical utility. Ann Pharmacother 35: 48-56, 2001.
Reilly MP.: Seizures associated with hypoxic-ischemic cardiopulmonary disorders. In: Seizures, Medical Causes and Management. Delanty N. Page: 233-250, 2001.
Reilly MP, Rader DJ.: Clinical decision-making in the management of lipid disorders. Disease Management and Clinical Outcome 3: 30-37, 2001.
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