Muredach P. Reilly, MBBCH, MSCE
Associate Professor of Medicine
Department: Medicine
Graduate Group Affiliations
Contact information
Translational Research Center
3400 Civic Center Blvd, Bldg 421
11th floor, Room 11-136
Philadelphia PA 19104
Philadelphia, PA 19104
3400 Civic Center Blvd, Bldg 421
11th floor, Room 11-136
Philadelphia PA 19104
Philadelphia, PA 19104
Office: (215) 573-1214
Lab: (215) 573-0224
Lab: (215) 573-0224
Email:
muredach@mail.med.upenn.edu
muredach@mail.med.upenn.edu
Publications
Links
Search PubMed for articles
Cardiovascular Institute: For in-depth information on the group's latest research efforts, visit the Reilly Group at the Penn Cardiovascular Institute
Institute for Translational Medicine and Therapeutics
Penn Health Profile
Search PubMed for articles
Cardiovascular Institute: For in-depth information on the group's latest research efforts, visit the Reilly Group at the Penn Cardiovascular Institute
Institute for Translational Medicine and Therapeutics
Penn Health Profile
Education:
MBBCh (Medicine)
University College, Dublin, Ireland, 1988.
BS (Pharmacology)
University College Dublin, Ireland , 1990.
MSCE (Epidemiology and Biostatistics)
University of Pennsylvania, 2003.
Permanent linkMBBCh (Medicine)
University College, Dublin, Ireland, 1988.
BS (Pharmacology)
University College Dublin, Ireland , 1990.
MSCE (Epidemiology and Biostatistics)
University of Pennsylvania, 2003.
Description of CVI Expertise
CVI Program Unit(s):CVI Research Description:
Dr. Reilly has extensive training and expertise in cardiovascular medicine, preventive cardiology, clinical pharmacology, epidemiology and translational research.
His interests include (1) mechanisms of atherosclerosis in metabolic syndrome, diabetes and obesity, (2) the role on innate immunity in promoting atherosclerotic risk in metabolic syndrome, (3) the functions of adipose tissue in regulation of HDL cholesterol and reverse cholesterol transport, (4) genetics of atherosclerosis and dyslipidemia in high risk populations including type 2 diabetes, subjects with family history of CAD, populations with chronic kidney disease and in HIV infected populations, and (5) non-invasive imaging of atherosclerosis in humans.
Dr. Reilly employs a translational approach to his research including cell and animal based mechanistic studies, mechanistic patient-oriented, General Clinical Research Center studies as well as larger scale epidemiological studies in humans.
Selected Publications
Olden M, Teumer A, Bochud M, Pattaro C, Köttgen A, Turner ST, Rettig R, Chen MH, Dehghan A, Bastardot F, Schmidt R, Vollenweider P, Schunkert H, Reilly MP, Fornage M, Launer LJ, Verwoert GC, Mitchell GF, Bis JC, O'Donnell CJ, Cheng CY, Sim X, Siscovick DS, Coresh J, Kao WH, Fox CS, O'Seaghdha CM; AortaGen, CARDIoGRAM, CHARGE Eye, CHARGE IMT, ICBP, NeuroCHARGE, and CKDGen Consortia. : Overlap Between Common Genetic Polymorphisms Underpinning Kidney Traits and Cardiovascular Disease Phenotypes: The CKDGen Consortium. Am J Kidney Dis. Mar 2013 Notes: doi:pii: S0272-6386(13)00029-2. 10.1053/j.ajkd.2012.12.024. [Epub ahead of print] PMID: 23474010.Chan K, Patel RS, Newcombe P, Nelson CP, Qasim A, Epstein SE, Burnett S, Vaccarino VL, Zafari AM, Shah SH, Anderson JL, Carlquist JF, Hartiala J, Allayee H, Hinohara K, Lee BS, Erl A, Ellis KL, Goel A, Schaefer AS, El Mokhtari NE, Goldstein BA, Hlatky MA, Go AS, Shen GQ, Gong Y, Pepine C, Laxton RC, Whittaker JC, Tang WH, Johnson JA, Wang QK, Assimes TL, Nöthlings U, Farrall M, Watkins H, Richards AM, Cameron VA, Muendlein A, Drexel H, Koch W, Park JE, Kimura A, Shen WF, Simpson IA, Hazen SL, Horne BD, Hauser ER, Quyyumi AA, Reilly MP, Samani NJ, Ye S. : Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis. J Am Coll Cardiol. 61(9): 957-70, Mar 2013 Notes: doi: 10.1016/j.jacc.2012.10.051. Epub 2013 Jan 23. PMID: 23352782.
Lieb W, Jansen H, Loley C, Pencina MJ, Nelson CP, Newton-Cheh C, Kathiresan S, Reilly MP, Assimes TL, Boerwinkle E, Hall AS, Hengstenberg C, Laaksonen R, McPherson R, Thorsteinsdottir U, Ziegler A, Peters A, Thompson JR, König IR, Erdmann J, Samani NJ, Vasan RS, Schunkert H; on behalf of CARDIoGRAM. : Genetic Predisposition to Higher Blood Pressure Increases Coronary Artery Disease Risk. Hypertension. Mar 2013 Notes: PMID: 23478099.
Qasim AN, Rafeek H, Rasania SP, Churchill TW, Yang W, Ferrari VA, Jha S, Master SM, Mulvey CK, Terembula K, Dailing C, Budoff MJ, Kawut SM, Reilly MP. : Cardiovascular risk factors and mitral annular calcification in type 2 diabetes. Atherosclerosis. 226(2): 419-24, Feb 2013 Notes: doi: 10.1016/j.atherosclerosis.2012.11.011. Epub 2012 Dec 5. PMID: 23273961.
Ganesh SK, Tragante V, Guo W, Guo Y, Lanktree MB, Smith EN, Johnson T, Castillo BA, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Franceschini N, Gaunt TR, Gho JM, Gieger C, Gong Y, Isaacs A, Kleber ME, Leach IM, McDonough CW, Meijs MF, Mellander O, Molony CM, Nolte IM, Padmanabhan S, Price TS, Rajagopalan R, Shaffer J, Shah S, Shen H, Soranzo N, van der Most PJ, Van Iperen EP, Van Setten JA, Vonk JM, Zhang L, Beitelshees AL, Berenson GS, Bhatt DL, Boer JM, Boerwinkle E, Burkley B, Burt A, Chakravarti A, Chen W, Cooper-Dehoff RM, Curtis SP, Dreisbach A, Duggan D, Ehret GB, Fabsitz RR, Fornage M, Fox E, Furlong CE, Gansevoort RT, Hofker MH, Hovingh GK, Kirkland SA, Kottke-Marchant K, Kutlar A, Lacroix AZ, Langaee TY, Li YR, Lin H, Liu K, Maiwald S, Malik R; CARDIOGRAM, METASTROKE, Murugesan G, Newton-Cheh C, O'Connell JR, Onland-Moret NC, Ouwehand WH, Palmas W, Penninx BW, Pepine CJ, Pettinger M, Polak JF, Ramachandran VS, Ranchalis J, Redline S, Ridker PM, Rose LM, Scharnag H, Schork NJ, Shimbo D, Shuldiner AR, Srinivasan SR, Stolk RP, Taylor HA, Thorand B, Trip MD, van Duijn CM, Verschuren WM, Wijmenga C, Winkelmann BR, Wyatt S, Young JH, Boehm BO, Caulfield MJ, Chasman DI, Davidson KW, Doevendans PA, Fitzgerald GA, Gums JG, Hakonarson H, Hillege HL, Illig T, Jarvik GP, Johnson JA, Kastelein JJ, Koenig W; LifeLines Cohort Study, März W, Mitchell BD, Murray SS, Oldehinkel AJ, Rader DJ, Reilly MP, Reiner AP, Schadt EE, Silverstein RL, Snieder H, Stanton AV, Uitterlinden AG, van der Harst P, van der Schouw YT, Samani NJ, Johnson AD, Munroe PB, de Bakker PI, Zhu X, Levy D, Keating BJ, Asselbergs FW. : Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum Mol Genet. Feb 2013 Notes: Feb 7. [Epub ahead of print] PMID: 23303523.
Scialla JJ, Lau WL, Reilly MP, Isakova T, Yang HY, Crouthamel MH, Chavkin NW, Rahman M, Wahl P, Amaral AP, Hamano T, Master SR, Nessel L, Chai B, Xie D, Kallem RR, Chen J, Lash JP, Kusek JW, Budoff MJ, Giachelli CM, Wolf M. : Fibroblast growth factor 23 is not associated with and does not induce arterial calcification. Kidney Int. Feb 2013 Notes: doi: 10.1038/ki.2013.3. [Epub ahead of print] PMID: 23389416.
Foulkes AS, Matthews GJ, Das U, Ferguson JF, Lin R, Reilly MP. : Mixed Modeling of Meta-Analysis P-Values (MixMAP) Suggests Multiple Novel Gene Loci for Low Density Lipoprotein Cholesterol. PLoS One. 8(2): e54812, Feb 2013 Notes: doi: 10.1371/journal.pone.0054812. Epub 2013 Feb 6. PMID: 23405096.
CARDIoGRAMplusC4D Consortium, Deloukas P, Kanoni S, Willenborg C, Farrall M, Assimes TL, Thompson JR, ..., Reilly MP, März W, Collins R, Kathiresan S, Hamsten A, Kooner JS, Thorsteinsdottir U, Danesh J, Palmer CN, Roberts R, Watkins H, Schunkert H, Samani NJ.: Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet. 2013 Jan;45(1):25-33. 45(1): 25-33, Jan 2013 Notes: doi: 10.1038/ng.2480. Epub 2012 Dec 2. PMID: 23202125.
Chen HY, Reilly MP, Li M. : Semiparametric odds ratio model for case-control and matched case-control designs. Stat Med. Jan 2013 Notes: doi: 10.1002/sim.5742. [Epub ahead of print] PMID: 23307592
Ferguson F Jane, Patel N Parth, Shah Y Rhia, Mulvey K Claire, Gadi Ram, Nijjar S Prabhjot, Usman M Haris, Mehta N Nehal, Shah Rachana, Master R Stephen, Propert J Kathleen, Reilly P Muredach: Race and gender variation in response to evoked inflammation Journal of Translational Medicine. 11(63), 2013 Notes: DOI: 10.1186/1479-5876-11-63 URL: http://www.translational-medicine.com/content/11/1/63.