Penn Cardiovascular Institute

Penn Cardiovascular Institute Research Directory

faculty photo

Reed E. Pyeritz, MD, PhD

William Smilow Professor
Department: Medicine

Contact information
Division of Translational Medicine and Human Genetics
University of Pennsylvania School of Medicine
11-133 Smilow Center for Translational Research, 3400 Civic Center Blvd
Philadelphia, PA 19104-4283
Office: 215-662-4740
Fax: 215-573-8606
Lab: 215-573-5746
S.B. (Chemistry)
University of Delaware, 1968.
A.M, Ph.D. (Biological Chemistry)
Harvard University, 1972.
Harvard Medical School, 1975.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Description of CVI Expertise

CVI Program Unit(s):
Cardiovascular Development / Congenital Heart Disease

CVI Research Description:
Involved in clinical and translational research in a variety of hereditary conditions that involve the cardiovascular system, especially Marfan syndrome, hereditary hemorrhagic telangiectasia and Ehlers-Danlos syndromes.

Selected Publications

Wagner JK, Mozersky JT, Pyeritz RE: Use it or lose it, as an alternative approach to protect genetic privacy in personalized medicine. Urol Oncol 32(2): 198-201, Feb 2014.

Pyeritz RE: Heritable thoracic aortic disorders. Curr Opin Cardiol 29(1): 97-102, Jan 2014.

Revencu N, Boon LM, Mendola A, Cordisco MR, Dubois J, Clapuyt P, Hammer F, Amor DJ, Irvine AD, Baselga E, Dompmartin A, Syed S, Martin-Santiago A, Ades L, Collins F, Smith J, Sandaradura S, Barrio VR, Burrows PE, Blei F, Cozzolino M, Brunetti-Pierri N, Vicente A, Abramowicz M, Désir J, Vilain C, Chung WK, Wilson A, Gardiner CA, Dwight Y, Lord DJ, Fishman L, Cytrynbaum C, Chamlin S, Ghali F, Gilaberte Y, Joss S, Boente Mdel C, Léauté-Labrèze C, Delrue MA, Bayliss S, Martorell L, González-Enseñat MA, Mazereeuw-Hautier J, O'Donnell B, Bessis D, Pyeritz RE, Salhi A, Tan OT, Wargon O, Mulliken JB, Vikkula M: RASA1 mutations and associated phenotypes in 68 families with capillary malformation-arteriovenous malformation. Hum Mutat 34(12): 1632-1641, Dec 2013.

Woodward CS, Pyeritz RE, Chittams JL, Trerotola SO: Treated pulmonary arteriovenous malformations: patterns of persistence and associated retreatment success. Radiology 269(3): 919-926, Dec 2013.

Bossone E, Pyeritz RE, O'Gara P, Harris KM, Braverman AC, Pape L, Russo MJ, Hughes GC, Tsai TT, Montgomery DG, Nienaber CA, Isselbacher EM, Eagle KA; International Registry of Acute Aortic Dissection (IRAD) Investigators.: Acute aortic dissection in blacks: insights from the International Registry of Acute Aortic Dissection. Am J Med 126(10): 909-915, Oct 2013.

Bossone E, Corteville DC, Harris KM, Suzuki T, Fattori R, Hutchison S, Ehrlich MP, Pyeritz RE, Steg PG, Greason K, Evangelista A, Kline-Rogers E, Montgomery DG, Isselbacher EM, Nienaber CA, Eagle KA: Stroke and outcomes in patients with acute type A aortic dissection. Circulation 128(11 Suppl 1): S175-S179, Sep 2013.

Reiff M, Mueller R, Mulchandani S, Spinner NB, Pyeritz RE, Bernhardt BA: A Qualitative Study of Healthcare Providers' Perspectives on the Implications of Genome-Wide Testing in Pediatric Clinical Practice. J Genet Couns Sep 2013 Notes: [Epub ahead of print]

Clark K, Pyeritz RE, Trerotola SO: Angina pectoris or myocardial infarctions, pulmonary arteriovenous malformations, hereditary hemorrhagic telangiectasia, and paradoxical emboli. Am J Cardiol 112(5): 731-734, Sep 2013.

Booher AM, Isselbacher EM, Nienaber CA, Trimarchi S, Evangelista A, Montgomery DG, Froehlich JB, Ehrlich MP, Oh JK, Januzzi JL, O'Gara P, Sundt TM, Harris KM, Bossone E, Pyeritz RE, Eagle KA; IRAD Investigators: The IRAD classification system for characterizing survival after aortic dissection. Am J Med 126(8): 730, Aug 2013.

Guo DC, Regalado E, Casteel DE, Santos-Cortez RL, Gong L, Kim JJ, Dyack S, Horne SG, Chang G, Jondeau G, Boileau C, Coselli JS, Li Z, Leal SM, Shendure J, Rieder MJ, Bamshad MJ, Nickerson DA; GenTAC Registry Consortium; National Heart, Lung, and Blood Institute Grand Opportunity Exome Sequencing Project, Kim C, Milewicz DM.: Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections. Am J Hum Genet 93(2): 398-404, Aug 2013.

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Last updated: 02/11/2014
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