Corey T McMillan

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Research Assistant Professor of Neurology
Member, University of Pennsylvania, Institute for Translational Medicine & Therapeutics
Department: Neurology

Contact information
University of Pennsylvania Perelman School of Medicine
Department of Neurology
3400 Spruce Street
3 West Gates
Philadelphia, PA 19104
Office: 215 614 0987
Fax: 215 349 8464
Lab: 215 349 5863
BA (Psychology & Cognitive Neuroscience)
Temple University, 2000.
MSc (Psycholinguistics)
University of Edinburgh, 2004.
PhD (Psychology)
University of Edinburgh, 2008.
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Description of Itmat Expertise

The overall aim of my research program is to develop robust biomarkers using neuroimaging, biofluid biomarkers, and genetics that can be used to better diagnose neurodegenerative disease like frontotemporal degeneration (FTD) and amyotrophic lateral sclerosis (ALS), accelerate drug discovery of disease-modifying agents, and to define essential clinical trial endpoint measures.

Description of Research Expertise

neurodegenerative disease, frontotemporal lobar degeneration, Alzheimer disease, neuroimaging, biomarkers, MRI, DTI, language, decision-making, cognition.

Selected Publications

McMillan, C. T., Irwin, D. J., Avants, B. B., Powers, J, Cook, P. A., Toledo, J. B., Wood, E. M., Van Deerlin, V. M., Lee, V. M.-Y., Trojanowksi, J. Q., & Grossman, M.: White matter imaging helps dissociate tau from TDP-43 in frontotemporal lobar degeneration. Journal of Neurology, Neurosurgery & Psychiatry 84(9): 949-955, 2013.

McMillan, C. T., Avants, B., Irwin, D. J., Toledo, J. B., Wolk, D. A., Van Deerlin, V. M., Shaw, L. M., Trojanowksi, J Q., & Grossman, M.: Can MRI screen for cerebrospinal fluid biomarkers in neurodegenerative disease? Neurology 80(2): 132-138, 2013.

McMillan C. T., Brun, C., Siddiqui, S., Churgin, M., Yuskevich, P., Zhang, H., Libon, D., Gee, J., & Grossman, M. : White matter imaging contributes to the multimodal diagnosis of frontotemporal lobar degeneration. Neurology 78(22): 1761-1768, 2012.

Avants, B., Dhillon, P., Kandel, B. M., Cook, P. A., McMilan, C. T., Grossman, M., & Gee, J.: Eigenanatomy improves detection power for longitudinal cortical change. Medical Image Computing & Computer Assisted Intervention: MICCAI 15(3): 206-213, 2012.

Irwin, D. J., McMillan, C. T., Brettschneider, J., Libon, D. J., Powers, J., Rascovsky, K., Toledo, J. B., Boller, A., Bekisz, J., Chandrasekaren, K., Wood, E. M., Shaw, L., Woo, J. H., Cook, P. A., Wolk, D. A., Arnold, S. E., Van Deerlin, V. M., McCluskey, L. F., Elman, L., Lee, V. M.-Y., Trojanowski, J. Q., & Grossman, M.: Cognitive decline and reduced survival in C9orf72 expansion frontotemporal degeneration and amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. 84(2): 163-169, 2013.

Irwin, D., McMillan, C. T., Toledo, J. B., Arnold, S. E., Shaw, L. M., Wang, L.-S., Lee, V.-Y., Trojanowski, J. Q., & Grossman, M.: Comparison of cerebrospinal fluid levels of tau and Abeta1-42 in Alzheimer's disease and frontotemporal degeneration using two analytical platforms. Archives of Neurology 69(8): 1018-1025, 2012.

Libon, D. J., McMillan, C., Avants, B., Boller, A., Morgan, B., Burkholder, L., Chandrasekaran, K., Elman, L., McCluskey, L., & Grossman, M.: Deficits in concept formation in amyotrophic lateral sclerosis. Neuropsychology 26(4): 422-429, 2012.

Grossman, M., Gross, R. G., Moore, P., Dreyfuss, M., McMillan, C. T., Cook, P. A., Ash, S., & Siderowf, A.: Difficulty processing temporary syntactic ambiguities in Lewy body spectrum disorder. Brain & Language 120(1): 52-60, 2012.

McMillan, C. T., Clark, R., Gunawardena, D., Ryant, N., & Grossman, M. : fMRI evidence for strategic decision-making during resolution of pronoun reference. Neuropsychologia 50(5): 674-687, 2012.

Ash, S., McMillan, C., Gross, R., G., Cook, P., Gunawardena, D., Morgan, B., Boller, A., Siderowf, A., & Grossman, M.: Impairments of speech fluency in Lewy body spectrum disorder. Brain & Language 120(3): 290-302, 2012.

Gross, R. G., McMillan, C. T., Chandrasekaran, K., Dreyfuss, M., Ash, S., Avants, B., Cook, P., Moore, P., Libon, D. J., Siderowf, A. & Grossman, M.: Sentence processing in Lewy body spectrum disorder: The role of working memory. Brain & Cognition 78(2): 85-93, 2012.

McMillan, C. T., Rascovsky, K., Khella, M. C., Clark, R., & Grossman, M.: The neural basis of establishing a focal point in pure coordination games. Social, Cognitive, & Affective Neuroscience 7(8): 881-887, 2012.

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Last updated: 09/11/2014
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