Natalie A Terry

faculty photo
Assistant Professor of Pediatrics
Clinical Associate, University of Pennsylvania School of Medicine
Department: Pediatrics

Contact information
The Children's Hospital of Philadelphia
3615 Civic Center Blvd
Abramson Research Center 1116-J
Philadelphia, PA 19104
Office: 267-426-7223
Graduate Group Affiliations
Education:
Sc.B. (Biochemistry)
Brown University, 1998.
M.D.
University of Pennsylvania School of Medicine, 2006.
Ph.D.
University of Pennsylvania School of Medicine, 2006.
Permanent link
 

Description of Research Expertise

The coordination of absorption, digestion, and motility of the intestine is orchestrated by the enteroendocrine cells. These cells are interspersed in the epithelial lining of the intestine in order to sense and process nutrients. Infants born without the intestinal endocrine cells have a severe malabsorptive diarrhea that is fatal without intravenous nutrition. Although this congenital diarrheal disorder has been described for some time, the mechanism for the malabsorption has not been elucidated. My work focuses on both the development of enteroendocrine cells and studies mouse models of congenital diarrhea to identify new therapeutic targets.

Description of Itmat Expertise

My research focuses on congenital diarrheal disorders and short bowel syndrome. The endocrine lineage of the intestine is critical in mediating digestion and absorption and without subpopulations of intestinal endocrine cells, a malabsorptive diarrhea results. To further characterize the mechanism of malabsorption, we use a combination mouse models and human tissue organoids.
back to top
Last updated: 07/10/2017
The Trustees of the University of Pennsylvania