Robert Gross

faculty photo
Associate Professor of Medicine
Attending Physician, Infectious Diseases, Philadelphia Veterans Administration Medical Center
Attending Physician, Infectious Diseases, Hospital of the University of Pennsylvania
Member, Abramson Cancer Center, University of Pennsylvania, Perelman School of Medicine
Senior Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Perelman School of Medicine
Senior Fellow, Leonard Davis Institute, University of Pennsylvania, Perelman School of Medicine
Co-Director, Center for AIDS Research Clinical Core, University of Pennsylvania, Perelman School of Medicine
Associate Fellow, Center for Public Health Initiatives, University of Pennsylvania, Perelman School of Medicine
Department: Medicine

Contact information
804 Blockley Hall
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania, Perelman School of Medicine
423 Guardian Drive
Philadelphia, PA 19104-6021
Office: 215-898-2437
Fax: 215-573-5315
Graduate Group Affiliations
Education:
B.A. (Italian)
Cornell University , 1986.
M.D.
Cornell University, 1991.
M.S.C.E. (Pharmacoepidemiology)
University of Pennsylvania, 2000.
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Description of Research Expertise

HIV clinical epidemiology; outcomes of HIV treatment; adherence to therapy including development of methods to measure adherence

Description of Itmat Expertise

Dr. Gross focuses on antiretroviral therapy for HIV with a primary focus on the relation between adherence to therapy and outcome and barriers to adherence and interventions to overcome barriers to adherence. He also conducts research on new antiretroviral agents as well as pharmacoepidemiology and pharmacogenetics of HIV drugs.

Selected Publications

Petersen ML, LeDell E, Schwab J, Sarovar V, Gross R, Reynolds N, Haberer JE, Goggin K, Golin C, Arnsten J, Rosen M, Remien R, Etoori D, Wilson I, Simoni JM, Erlen JA, van der Laan MJ, Liu H, Bangsberg DR: Super learner analysis of electronic adherence data improves viral prediction and may provide strategies for selective HIV RNA monitoring. JAIDS 2014 (in press).

Lowenthal ED, Marukutira T, Tshume O, Chapman J, Nachega J,Anabwani G, Gross R : Parental Absence from Clinic Predicts HIV Treatment Failure in Adolescents. JAMA Pediatrics 2014 (in press).

Liu C, Sadik M, Mauk M, Edelstein PH, Bushman FD, Gross R, Bau H: Nuclemeter: A Reaction-Diffusion based Method for Quantifying Nucleic Acids Undergoing Enzymatic Amplification. Scientific Reports 2014 (in press).

Gross R, Zheng L, La Rosa A, Sun X, Rosenkranz SL, Wagner Cardoso S, Ssali F, Camp R, Godfrey C, Cohn SE, Robbins GK, Chisada A, Wallis CL, Reynolds NR, Lu D, Safren SA, Hosey L, Severe P, Collier AC.: Partner-Focused Adherence Intervention for Second-line Antiretroviral Therapy: A Multinational Randomized Trial (ACTG A5234). Lancet HIV (in press). Lancet HIV 2014 (in press).

Mills EJ, Lester R, Thorlund K, Lorenzi M, Muldoon K, Kanters S, Linnemayr S, Gross R, Calderone Y, Amico KR, Thirumurthy H, Pearson C, Remien RH, Mbuagbaw L, Thabane L, Chung MH, Wilson IB, Liu A, Uthman OA, Simoni J, Bangsberg D, Yaya S, Barnighausen T, Ford N, Nachega JB: Interventions to improve adherence to antiretroviral therapy in Africa: a network meta-analysis. Lancet HIV 1, Dec 2014.

Simoni JM, Huh D, Wang Y, Wilson IB, Reynolds NR, Remien RH, Goggin K, Gross R, Rosen MI, Schneiderman N, Arnsten J, Golin CE, Erlen JA, Bangsberg D, and Liu H for MACH14 Investigators: The Validity of Self-Reported Medication Adherence as an Outcome in Clinical Trials of Adherence-Promotion Interventions: Findings from the MACH14 Study AIDS and Behavior epub ahead of print, Oct 2014 Notes: In Press.

Lowenthal E, Marukutira T, Chapman, J Mokete K, Riva K, Tshume O, Eby J, Matshaba M, Anabwani G, Gross R, Glanz K: Psychosocial Assessments for HIV+ African Adolescents: Establishing Construct Validity and Exploring Under-appreciated Correlates of Adherence PLoS ONE 9(10): e109302, Oct 2014.

Gross R, Bandason T, Langhaug L, Mujuru H, Lowenthal E, Ferrand R : Factors Associated with Self-Reported Adherence among Adolescents on Antiretroviral Therapy in Zimbabwe. AIDS Care epub ahead of print: 1-5, Oct 2014 Notes: In Press.

Sonenthal PD, Ratshaa B, Chimbengo G, Rantleru T, Ngoni T, Barenbaum S, Platoff R, Steenhoff AP, Gross R: Baseline Predictors of Efavirenz-Containing Antiretroviral Regimen Adverse Experiences. Pharmacoepidemiology and Drug Safety 23(7): 773-7, July 2014.

Nachega JB,Parienti JJ, Uthman OA, Gross R, Dowdy DW, Sax PE, Gallant JE, Mugavero MJ, Mills EJ, Giordano TP.: Effect of Once-daily Dosing and Lower Pill Burden Antiretroviral Regimens for HIV Infection: A Meta-Analysis of Randomised Controlled Trials. Clinical Infectious Diseases 58(9): 1297-307, May 2014.

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Last updated: 12/08/2014
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