Melpo Christofidou-Solomidou

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Research Associate Professor of Medicine
Director, Pulmonary Morphology Core Laboratory, University of Pennsylvania School of Medicine, Philadelphia, PA
Investigator, Center for Excellence in Environmental Toxicology (CEET), University of Pennsylvania
Investigator, Abramson Cancer Center, University of Pennsylvania
Adjunt Faculty, Institute for Environmental Medicine (IFEM), University of Pennsylvania
Department: Medicine

Contact information
University of Pennsylvania, Department of Medicine
Pulmonary, Allergy and Critical Care Division
3615 Civic Center Boulevard
Abramson Research Center, Office Suite 1016C
Philadelphia, PA 19104-6160
Office: (215) 573-9917
Fax: (215) 573-4469
B.S. (Biology)
State University of New York at Stony Brook, Long Island, New York, 1983.
M.S. (Cell Biology)
Rhenish Friedrich Wilhelm’s University, Bonn, Germany, 1987.
Ph.D. (Cell Biology)
Rhenish Friedrich Wilhelm’s University, Bonn, Germany, 1991.
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Description of Research Expertise

The theme of Dr. Christofidou-Solomidou's research is pulmonary inflammation and cell adhesion molecule regulation/expression. Projects involve the development of oxidant-induced acute and chronic lung injury animal models for the study of diseases such as ARDS, sepsis, radiation induced pneumonitis/fibrosis, and oxygen toxicity. Specific projects focus on the development of antioxidant methodologies such as immune conjugates for the targeting of anti-oxidant enzymes such as Catalase and Superoxide Dismutase to the pulmonary endothelium using antibodies to endothelial antigens. Recent work extends to the use of dietary alternative antioxidant agents such as curcumin, flaxseed or phenolic compounds in ameliorating acute and chronic oxidative lung disease.

Description of Itmat Expertise

Dr. Christofidou-Solomidou studies pulmonary inflammation, cell adhesion molecule regulation/ expression and acute/chronic lung injury.
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Last updated: 01/31/2014
The Trustees of the University of Pennsylvania