Anil Vachani

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Assistant Professor of Medicine at the Hospital of the University of Pennsylvania and the Veteran's Administration Medical Center
Attending Physician, Philadelphia Veterans Administration Medical Center
Contributor, Ask-the-Experts Board, Oncolink, University of Pennsylvania Health System
Staffing of eICU at the University of Pennsylvania Health System, 1x/month, University of Pennsylvania
Director of Clinical Research, Section of Interventional Pulmonology and Thoracic Oncology, Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania School of Medicine
Director, Lung Nodule Program, Perelman School of Medicine, Univeristy of Pennsylvania
Director of Bronchoscopy, Philadelphia VA Medical Center
Department: Medicine

Contact information
Pulmonary, Allergy, and Critical Care Division
University of Pennsylvania School of Medicine
CHOP/Abramson Research Center, Room 1016E
3615 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215.573.7931
Fax: 215.573.4469
Education:
B.S. (Genetics)
University of California, Berkeley, 1992.
B.A. (Economics)
University of California, Berkeley, 1992.
M.D. (Medicine)
University of California, San Francisco, 1996.
M.S. (Clinical Epidemiology)
University of Pennsylvania, Perelman School of Medicine, 2013.
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Description of Itmat Expertise

Dr. Vachani is interested in the molecular epidemiology of lung cancer and in discovery and validation of early detection biomarkers for thoracic malignancies. His research ranges from animal models to human translational studies and includes observational and correlative studies in early and late phase clinical trials.

Selected Publications

Eruslanov E.B., Bhojnagarwala P.S., Quatromoni J.G., Stephen T.L., Ranganathan A., Deshpande C., Akimova T., Vachani A., Litzky L., Hancock W.W., Conejo-Garcia J.R., Feldman M., Albelda S.M., Singhal S.: Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer. The Journal of clinical investigation 124(12): 5466-80, Dec 2014.

Vachani A., Tanner N.T., Aggarwal J., Mathews C., Kearney P., Fang K.C., Silvestri G., Diette G.B.: Factors That Influence Physician Decision-making for Indeterminate Pulmonary Nodules. Annals of the American Thoracic Society Nov 2014.

Mazzone P.J., Vachani A., Chang A., Detterbeck F., Cooke D., Howington J., Dodi A., Arenberg D.: Quality Indicators for the Evaluation of Patients with Lung Cancer. Chest 146(3): 659-69, September 2014.

Wu Y., Kwak K.J., Agarwal K., Marras A., Wang C., Mao Y., Huang X., Ma J., Yu B., Lee R., Vachani A., Marcucci G., Byrd J.C., Muthusamy N., Otterson G. Huang K. Castro C.E., Paulaitis M., Nana-Sinkam S.P., Lee L.J.: Detection of Extracellular RNAs in Cancer and Viral Infection via Tethered Cationic Lipoplex Nanoparticles Containing Molecular Beacons. Analytical Chemistry 85(23): 11265-74, Dec 2013.

Schwed Lustgarten D.E., Thompson J., Yu G., Vachani A., Vaidya B., Rao C., Connelly M., Udine M., Tan K.S., Heitjan D.F., Albelda S.: Use of Circulating Tumor Cell Technology (CELLSEARCH®) for the Diagnosis of Malignant Pleural Effusions. Annals of the American Thoracic Society 10(6): 582-9, December 2013.

Baldwin D.A., Sarnowski C.P., Reddy S.A., Blair I.A., Clapper M., Lazarus P., Li M., Muscat J.E., Penning T.M., Vachani A., Whitehead A.S.: Development of a genotyping microarray for studying the role of gene-environment interactions in risk for lung cancer. Journal of Biomolecular Techniques : JBT 24(4): 198-217, Dec 2013.

Li X.L., Hayward C., Fong P.Y., Dominguez M., Hunsucker S.W., Lee L.W., McLean M., Law S., Butler H., Schirm M., Gingras O., Lamontagne J., Allard R., Chelsky D., Price N.D., Lam S., Massion P.P., Pass H., Rom W.N., Vachani A., Fang K.C., Hood L., Kearney P.: A blood-based proteomic classifier for the molecular characterization of pulmonary nodules. Science Translational Medicine 5(207): 207ra142, Oct 2013.

Bauml J., Mick R., Zhang Y., Watt C.D., Vachani A., Aggarwal C., Evans T., Langer C. : Frequency of EGFR and KRAS mutations in patients with non small cell lung cancer by racial background: Do disparities exist? Lung Cancer 81(3): 347-53, Sep 2013.

Bauml J., Mick R., Zhang Y., Watt C.D., Vachani A., Aggarwal C., Evans T., Langer C.: Determinants of Survival in Advanced Non-Small-Cell Lung Cancer in the Era of Targeted Therapies. Clinical Lung Cancer 14(5): 581-91, Sep 2013.

Baek K.H., Bhang D, Zaslavsky A., Wang L.C., Vachani A., Kim C.F., Albelda S.M., Evan G.I., Ryeom S.: Thrombospondin-1 mediates oncogenic Ras-induced senescence in premalignant lung tumors. The Journal of Clinical Investigation 123(10): 4375-89, Sep 2013.

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Last updated: 12/17/2014
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