Anil Vachani
Assistant Professor of Medicine at the Hospital of the University of Pennsylvania and the Veteran's Administration Medical Center
Attending Physician, Philadelphia Veterans Administration Medical Center
Contributor, Ask-the-Experts Board, Oncolink, University of Pennsylvania Health System
Faculty-Fellow, Center for Clinical Epidemiology & Biostatistics - University of Pennsylvania School of Medicine
Staffing of eICU at the University of Pennsylvania Health System, 1x/month, University of Pennsylvania
Director of Clinical Research, Section of Interventional Pulmonology and Thoracic Oncology, Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania School of Medicine
Director, Lung Nodule Program, Perelman School of Medicine, Univeristy of Pennsylvania
Department: Medicine
Contact information
Pulmonary, Allergy, and Critical Care Division
University of Pennsylvania School of Medicine
CHOP/Abramson Research Center, Room 1016E
3615 Civic Center Boulevard
Philadelphia, PA 19104
University of Pennsylvania School of Medicine
CHOP/Abramson Research Center, Room 1016E
3615 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215.573.7931
Fax: 215.573.4469
Fax: 215.573.4469
Email:
avachani@mail.med.upenn.edu
avachani@mail.med.upenn.edu
Education:
B.S. (Genetics)
University of California, Berkeley, 1992.
B.A. (Economics)
University of California, Berkeley, 1992.
M.D. (Medicine)
University of California, San Francisco, 1996.
Permanent linkB.S. (Genetics)
University of California, Berkeley, 1992.
B.A. (Economics)
University of California, Berkeley, 1992.
M.D. (Medicine)
University of California, San Francisco, 1996.
Description of Itmat Expertise
Dr. Vachani is interested in the molecular epidemiology of lung cancer and in discovery and validation of early detection biomarkers for thoracic malignancies. His research ranges from animal models to human translational studies and includes observational and correlative studies in early and late phase clinical trials.Selected Publications
Lustgarten D.E., Deshpande C., Aggarwal C., Wang, L.C., Saloura V., Vachani A., Wang L.P., Litzky L., Feldman M., Creaney J., Nowak A., Langer C., Inguilleri S., Stella G., Albelda S.M.: Thymidylate Synthase and Folyl-polyglutamate synthase (FPGS) Are Not Clinically Useful Markers of Response to Pemetrexed in Patients with Malignant Pleural Mesothelioma. Journal of Thoracic Oncology 2013, in press.Rengan R., Mitra N., Liao K., Armstrong K., Vachani A. : Impact of HIV infection on survival in non-small cell lung cancer patients in the era of Highly Active Anti Retroviral Therapy: A Population-Based Study. Lancet Oncology 13(12): 1203-9, Dec 2012.
Handorf EA, McElligott S, Vachani A, Langer CJ, Bristol Demeter M, Armstrong K, Asch DA: Cost Effectiveness of Personalized Therapy for First-Line Treatment of Stage IV and Recurrent Incurable Adenocarcinoma of the Lung J Oncol Pract 8(5): 267-74, September 2012.
Patnaik SK, Yendamuri S, Kannisto E, Kucharczuk JC, Singhal S, Vachani A. : MicroRNA Expression Profiles of Whole Blood in Lung Adenocarcinoma. PLoS One 7(9): e46045, September 2012.
Mesaros C., Arora J.S., Wholer A., Vachani A., Blair I.A.: 8-Oxo-2'-deoxyguanosine as a biomarker of tobacco-smoking-induced oxidative stress. Free Radic Biol Med 53(3): 610-7, Aug 2012.
Mesaros C., Arora J.S., Wholer A., Vachani A., Blair I.A.: 8-Oxo-2'-deoxyguanosine as a biomarker of tobacco-smoking-induced oxidative stress. Free Radical Biology & Medicine 53(3): 610-617, May 2012.
O'Shannessy D.J., Yu G., Smale R., Fu Y.S., Singhal S., Thiel R.P., Somers E.B., Vachani A.: Folate Receptor Alpha Expression in Lung Cancer: Diagnostic and Prognostic Significance. Oncotarget Apr 2012.
Hanai Y., Shimono K., Matsumura K., Vachani A., Albelda S., Yamazaki K., Beauchamp G.K., Oka H.: Urinary volatile compounds as biomarkers for lung cancer. Bioscience, Biotechnology, and Biochemistry 76(4): 679-84, Apr 2012.
Zhou C., Licciulli S., Avila J.L., Cho M., Troutman S., Jiang P., Kossenkov A.V., Showe L.C., Liu Q., Vachani A., Albelda S.M., Kissil J.L.: The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis. Oncogene Mar 2012.
Schwartz L.E., Aisner D.L., Baloch Z.W., Sterman D.H., Vachani A., Gillespie C., Haas A., Litzky L.A.: The diagnostic efficacy of combining bronchoscopic tissue biopsy and endobronchial ultrasound-guided transbronchial needle aspiration for the diagnosis of malignant lesions in the lung. Diagnostic Cytopathology Feb 2012.