Adam Bagg

faculty photo
Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
Attending in Hematopathology, Laboratory Hematology, Flow Cytometry and Molecular Pathology, Hospital of the University of Pennsylvania
Director, Hematology, Hospital of the University of Pennsylvania
Department: Pathology and Laboratory Medicine

Contact information
Department of Pathology and Laboratory Medicine
Hospital of the University of Pennsylvania
7.103 Founders Pavilion
3400 Spruce Street
Philadelphia, PA 19104-4283
Office: 215-662-4280
Fax: 215-662-7529
Education:
MB. BCh (magna cum laude)
University of the Witwatersrand, South Africa, Top 1% of graduating class, 1981.
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Description of Research Expertise

Molecular genetics and pathology of Leukemias and Lymphomas; Myelodysplastic syndromes; Minimal residual disease; Hodgkin lymphoma

Description of Itmat Expertise

Dr. Bagg studies: (1) the diagnostic molecular pathology of hematologic malignancies, with the development of novel assays to facilitate their diagnosis; (2) minimal residual disease testing in leukemia, lymphoma and myeloma; and (3) unraveling the biology and improving the laboratory diagnosis of the myelodysplastic syndromes.

Selected Publications

Wang SA, Hasserjian RP, Tam W, Tsai AG, Geyer JT, George TI, Foucar K, Rogers HJ, Hsi ED, Rea BA, Bagg A, Bueso-Ramos C, Arber DA, Verstovsek S, Orazi A: Bone marrow morphology is a strong discriminator between chronic eosinophilic leukemia, not otherwise specified from reactive idiopathic hypereosinophilic syndrome. Haematologica May 11 2017 Notes: pii: haematol.2017.165340. doi: 10.3324/haematol.2017.165340. [Epub ahead of print]

Geyer JT, Tam W, Liu YC, Chen Z, Wang SA, Bueso-Ramos C, Oak J, Arber DA, Hsi E, Rogers HJ, Levinson K, Bagg A, Hassane DC, Hasserjian RP, Orazi A: Oligomonocytic chronic myelomonocytic leukemia (chronic myelomonocytic leukemia without absolute monocytosis) displays a similar clinicopathologic and mutational profile to classical chronic myelomonocytic leukemia. Mod Pathol May 26 2017 Notes: doi: 10.1038/modpathol.2017.45. [Epub ahead of print]

Xu Y, Wertheim G, Morrissette JJ, Bagg A: BRAF kinase domain mutations in de novo acute myeloid leukemia with monocytic differentiation. Leukemia Lymphoma 58(3): 743-745, 2017.

Fajgenbaum DC, Uldrick TS, Bagg A, Frank D, Wu D, Srkalovic G, Simpson D, Liu AY, Menke D, Chandrakasan S, Lechowicz MJ, Wong RS, Pierson S, Paessler M, Rossi JF, Ide M, Ruth J, Croglio M, Suarez A, Krymskaya V, Chadburn A, Colleoni G, Nasta S, Jayanthan R, Nabel CS, Casper C, Dispenzieri A, Fosså A, Kelleher D, Kurzrock R, Voorhees P, Dogan A, Yoshizaki K, van Rhee F, Oksenhendler E, Jaffe ES, Elenitoba-Johnson KS, Lim MS: International, evidence-based consensus diagnostic criteria for HHV-8-negative/idiopathic multicentric Castleman disease. Blood 129: 1646-1657, 2017.

Caponetti G, Bagg A: Demystifying the Diagnosis and Classification of Lymphoma: A Hematologist/Oncologist's Guide to the Hematopathologist's Galaxy. Journal of Community and Supportive Oncology 15: 43-48, 2017.

Wertheim GBW, Bagg A: NPM1 for MRD? Droplet Like It’s Hot. Journal of Molecular Diagnosis 19: 498-501, 2017.

Levinson KB, Bagg A: Atypical Chronic Myeloid Leukemia in Precision Molecular Pathology of Myeloid Neoplasms. Springer. Chung-Che Chang, Robert Ohgami (eds.). 2017.

Rogers HJ, Hsi ED, Tang G, Wang SA, Bueso-Ramos CE, Lubin D, Morrissette JJ, Bagg A, Cherukuri DP, George TI, Peterson L, Liu YC, Mathew S, Orazi A, Hasserjian RP : Most Myeloid Neoplasms with Deletion of Chromosome 16q are distinct from Acute Myeloid Leukemia with inv(16)(p13.1q22): A Bone Marrow Pathology Group Multicenter Study. Am J Clin Pathol 147: 411-419, 2017.

Wang Sa A, Tam Wayne, Tsai Albert G, Arber Daniel A, Hasserjian Robert P, Geyer Julia T, George Tracy I, Czuchlewski David R, Foucar Kathryn, Rogers Heesun J, Hsi Eric D, Bryan Rea B, Bagg Adam, Dal Cin Paola, Zhao Chong, Kelley Todd W, Verstovsek Srdan, Bueso-Ramos Carlos, Orazi Attilio: Targeted next-generation sequencing identifies a subset of idiopathic hypereosinophilic syndrome with features similar to chronic eosinophilic leukemia, not otherwise specified. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc May 2016 Notes: E-pub ahead of Print.

Bhoj Vijay G, Arhontoulis Dimitrios, Wertheim Gerald, Capobianchi James, Callahan Colleen A, Ellebrecht Christoph T, Obstfeld Amrom E, Lacey Simon F, Melenhorst Jan J, Nazimuddin Farzana, Hwang Wei-Ting, Maude Shannon L, Wasik Mariusz A, Bagg Adam, Schuster Stephen, Feldman Michael D, Porter David L, Grupp Stephen A, June Carl H, Milone Michael C: Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T cell therapy. Blood May 2016 Notes: E-pub ahead of Print.

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Last updated: 11/08/2017
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