David F. Friedman

faculty photo
Clinical Associate Professor of Pediatrics
Transfusion Committee, The Children's Hospital of Philadelphia
Associate Director of Blood Bank, The Children's Hospital of Philadelphia
Associate Director of Apheresis Service, The Children's Hospital of Philadelphia
Transfusion Practice Committee, Penn Jersey American Red Cross
Medical Director , Phlebotomy Service
Clinical Decision Support, renamed Clinical Informatics Council, Children's Hospital of Philadelphia
ECMS-IS, renamed CITAC, Children's Hospital of Philadelphia
ISSR review committee, Children's Hospital of Philadelphia, Department of Pathology
LIS Governance (Pathology), Children's Hospital of Philadelphia, Department of Pathology
Rational Dosing of Prophylactic Platelet Transfusion in Non Bleeding Patients, American Board of Pediatrics and Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
CHOP Main Room 5132
Philadelphia, PA 19104
Office: 2155902264
BA (Physics)
Yale University, 1979.
University of Pennsylvania, 1984.
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Description of Research Expertise

Transfusion medicine, Apheresis, Rh genes and alloimmunization

Description of Other Expertise

Clinical Database design and query

Description of Itmat Expertise

Dr. Friedman is investigating the use of the Amicus cell separator in red cell exchange transfusions.

Selected Publications

Stanley Helen M, Friedman David F, Webb Jennifer, Kwiatkowski Janet L: Transfusional Iron Overload in a Cohort of Children with Sickle Cell Disease: Impact of Magnetic Resonance Imaging, Transfusion Method, and Chelation. Pediatric blood & cancer 63(8): 1414-8, Aug 2016.

Cohen Devin, Hartung Helge, Evans Perry, Friedman David F, Chou Stella T: Red blood cell alloimmunization in transfused patients with bone marrow failure syndromes. Transfusion 56(6): 1314-9, Jun 2016.

Lancaster Diana P, Friedman David F, Chiotos Kathleen, Sullivan Kaede V: Blood Volume Required for Detection of Low Levels and Ultralow Levels of Organisms Responsible for Neonatal Bacteremia by Use of Bactec Peds Plus/F, Plus Aerobic/F Medium, and the BD Bactec FX System: an In Vitro Study. Journal of clinical microbiology 53(11): 3609-13, Nov 2015.

Godefroy Emmanuelle, Zhong Hui, Pham Petra, Friedman David, Yazdanbakhsh Karina: TIGIT-positive circulating follicular helper T cells display robust B-cell help functions: potential role in sickle cell alloimmunization. Haematologica 100(11): 1415-25, Nov 2015.

Casas Jessica, Friedman David F, Jackson Tannoa, Vege Sunitha, Westhoff Connie M, Chou Stella T: Changing practice: red blood cell typing by molecular methods for patients with sickle cell disease. Transfusion 55(6 Pt 2): 1388-93, Jun 2015.

Jobes David R, Sesok-Pizzini Deborah, Friedman David: Reduced transfusion requirement with use of fresh whole blood in pediatric cardiac surgical procedures. The Annals of thoracic surgery 99(5): 1706-11, May 2015.

Zhong Hui, Bao Weili, Friedman David, Yazdanbakhsh Karina: Hemin controls T cell polarization in sickle cell alloimmunization. Journal of immunology (Baltimore, Md. : 1950) 193(1): 102-10, Jul 2014.

Gálvez Jorge A, Ahumada Luis, Simpao Allan F, Lin Elaina E, Bonafide Christopher P, Choudhry Dhruv, England William R, Jawad Abbas F, Friedman David, Sesok-Pizzini Debora A, Rehman Mohamed A: Visual analytical tool for evaluation of 10-year perioperative transfusion practice at a children's hospital. Journal of the American Medical Informatics Association : JAMIA 21(3): 529-34, May-Jun 2014.

Chou Stella T, Jackson Tannoa, Vege Sunitha, Smith-Whitley Kim, Friedman David F, Westhoff Connie M: High prevalence of red blood cell alloimmunization in sickle cell disease despite transfusion from Rh-matched minority donors. Blood 122(6): 1062-71, Aug 2013.

Weiss Pamela F, Klink Andrew J, Friedman David F, Feudtner Chris: Pediatric therapeutic plasma exchange indications and patterns of use in US children's hospitals. Journal of clinical apheresis 27(6): 287-94, 2012.

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Last updated: 03/09/2018
The Trustees of the University of Pennsylvania