John H. Holmes

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Professor of Medical Informatics in Epidemiology in Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania
Senior Fellow, Leonard Davis Institute of Health Economics, Wharton School, University of Pennsylvania
Senior Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine
Senior Fellow, Center for Public Health Initiatives, School of Medicine University of Pennsylvania
Associate Professor (secondary), University of Pennsylvania School of Nursing
Department: Biostatistics and Epidemiology

Contact information
726 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104
Office: 215-898-4833
Fax: 215-573-5325
A.B. (Sociology)
University of Pennsylvania, 1976.
M.S. (Information Systems)
Drexel University, 1987.
Ph.D. (Information Science)
Drexel University, 1996.
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Description of Research Expertise

medical informatics; data mining; evolutionary computation; machine learning; artificial intelligence; database design and implementation for clinical research; medical decision making;

Description of Itmat Expertise

Dr. Holmes is studying epidemiologic informatics, using large databases for clinical research, and the development of evolutionary computational approaches for knowledge discovery (data mining). Research includes creating and applying knowledge discovery methods for the analysis of gene-environment interactions and pursuit of associations between HLA residue mismatch patterns in renal allografts and various clinical outcomes.

Selected Publications

Maro JC, Platt R, Holmes JH, Strom BL, Hennessy S, Lazarus R, Brown JS: Design of a national distributed health data network. Annals of Internal Medicine 151(5): 1-4, July 2009.

Bowles KH, Holmes JH, Ratcliffe SJ, Liberatore M, Nydick R, Naylor MD: Factors Identified by Experts to Support Decision Making for Post-Acute Referral. Nursing Research 58(2): 115-122, In Press 2009.

Safran C, Shabot MM, Munger BS, Holmes JH, Steen EB, Lumpkin JR, Detmer DE: ACGME Program Requirements for Fellowship Education in the Subspecialty of Clinical Informatics. Journal of the American Medical Informatics Association December (epub ahead of print) 2008.

Kamoun M**, Holmes JH**, Israni AK, Kearns JD, Teal V, Yang WP, Rosas SE, Joffe MM, Li H, Feldman HI: HLA-A amino acid polymorphism and delayed kidney allograft function. Proceedings of the National Academy of Sciences 105(48): 18883-18888, December 2008 Notes: Co-first author.

Gardner RM, Overhage JM, Steen EB, Munger BS, Holmes JH, Williamson JJ, Detmer DE: Core Content for the Subspecialty of Clinical Informatics. Journal of the American Medical Informatics Association December (epub ahead of print) 2008.

Holmes JH, Lehman A, Hade E, Ferketich A, Gehlert S, Rauscher GH, Abrams J, Bird C: Challenges to Multi-Level Analysis in Health Disparities Research in a transdisciplinary environment. American Journal of Preventive Medicine 35(2): 182-192, August 2008.

Baumgarten M, Margolis DJ, Localio AR, Kagan SH, Lowe RA, Kinosian B, Holmes JH, Abbuhl SB, Kavesh W, Ruffin A, Mehari T: Extrinsic risk factors for pressure ulcers early in the hospital stay: A nested case-control study. Journal of Gerontology: Medical Sciences 63(4): 408-413, April 2008.

Bowles KH, Holmes JH, Ratcliffe SJ, Liberatore M, Nydick R, Naylor MD: Post-acute referral decisions made by multidisciplinary experts compared to hospital clinicians and the patients' 12-week outcomes. Medical Care 46(2): 158-166, February 2008.

Bair-Merritt MH, Holmes WC, Holmes JH, Feinstein J, Feudtner C : Does Intimate Partner Violence Epidemiology Differ Between Homes With and Without Children? A Population-Based Study of Annual Prevalence and Associated Risk Factors. Journal of Family Violence February 2008 Notes: accepted August 2007; published online February 18, 2008.

Nguyen GT, Barg FK, Armstrong K, Holmes JH, Hornik RC: Cancer and communication in the healthcare setting: Experiences of older Vietnamese immigrants, a qualitative study. Journal of General Internal Medicine 23(1): 45-50, January 2008.

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Last updated: 10/30/2014
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