Bruce Joseph Giantonio

faculty photo
Associate Professor of Medicine at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia
Department: Medicine

Contact information
Division of Hematology Oncology
Perelman Center for Advanced Medicine
10th Floor, South Pavilion
Office #10-304
3400 Civic Center Blvd.
Philadelphia, PA 19104
Office: 215-662-6318
Fax: 215-349-5326

St. Michael’s College, 1979.
BA (Biology)
Hofstra University, 1980.
MS (Physiology/Biophysics)
Georgetown University, 1983.
Georgetown University, 1987.
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Description of Research Expertise

Clinical Investigation of targeted agents in gastrointestinal malignancies

Description of Itmat Expertise

Dr. Giantonio is developing new and novel agents for the treatment of gastrointestinal malignancies.

Selected Publications

Dolinsky, C.M., Mahmoud, N.N., Sun, W., Whittington, R.W., Solin, L.J., Haller, D.G., Giantonio, B.J., O’Dwyer, P.J., Rosato, E.F., Fry, R.D., Metz, J.M. : Effect of time interval between surgery and preoperative chemoradiotherapy with 5-Fluorouracil or 5-fluorouracil and oxaliplatin on outcomes in rectal cancer. J Surg Oncol 96(3): 207-212, 2007.

Giantonio, B., Catalano, P.J., Meropol, N.J., O’Dwyer, P.J., Michell, E. P., Alberts, S.R., Schwartz, M.A., Benson, A.B. : Bevacizumab in Combination with Oxaliplatin, Fluorouracil and Leucovorin (FOLFOX4) for Previously Treated Metastatic Colorectal Cancer: Results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol 25(12): 1539-1544, 2007.

Giantonio, B.J.: Bevacizumab in the treatment of metastatic colorectal cancer (mCRC) in second- and third-line settings. Seminars in Oncology 33(5 Suppl 10): S15-8, 2006.

Giantonio, B., Levy, D., O’Dwyer, P., Meropol, N., Catalano, P., Benson, A. 3rd: A Phase II study of high-dose bevacizumab in combination with irinotecan, 5-fluorouracil, leucovorin, as initial therapy for advanced colorectal cancer: results from the Eastern Cooperative Group Study E2200 Ann Oncol 17(9): 1399-1403, 2006.

Veronese, M.L., Sun, W., Giantonio, B., Berlin, J., Shults, J., Davis, L., Haller, D.G., O'Dwyer, P.J. : A phase II trial of gefitinib with 5-fluorouracil, leucovorin, and irinotecan in patients with colorectal cancer. British Journal of Cancer 92(10): 1846-1849, 2005.

Bilenker, J.H., Flaherty, K.T., Rosen, M., Davis, L., Gallagher, M., Stevenson, J.P. Sun, W., Vaughn, D., Giantonio, B., Zimmer, R., Schnall, M., O'Dwyer, P.J.: Phase I trial of combretastatin a-4 phosphate with carboplatin. Clin Cancer Research 11(4): 1527-1533, 2005.

Bilenker, J.H., Stevenson, J.P., Flaherty K.T., Algazy, K., McLaughlin, K., Haller, D.G., Giantonio, B.J., Koehler, M., Garcia-Vargas, J.E., O’Dwyer, P.J.: Phase I trial of the antifolate ZD9331 in combination with cisplatin in patients with refractory solid malignancies. Cancer Chemother Pharmacol 53(4): 357-360, April 2004.

Giantonio, B.J., Derry, C., McAleer, C., McPhillips, J.J., O’Dwyer, P.J: Phase I and pharmacokinetic study of the cytotoxic ether lipid ilmofosine administered by weekly 2 hour infusion in patients with advanced solid tumors Clin Cancer Research 10: 1282-1288, 2004.

Sun, W., Whittington, R., Gallagher, M., O'Dwyer, P., Giantonio, B., Metz, J., Haller, D. : Concurrent RT with 5-FU/epirubicin and cisplatin or irinotecan for locally advanced upper GI adenocarcinoma. Oncology. 18((14 Suppl 14)): 39-42, 2004.

Veronese, M.L., Stevenson, J.P., Sun, W., Redlinger, M., Algazy, K., Giantonio, B., Hahn, S., Vaughn, D., Thorn, C., Whitehead, A.S., Haller, D.G., O’Dwyer, P.J. : Phase I trial of UFT/Leucovorin and irinotecan in patients with advanced cancer. Eur J Cancer 40: 508-514, 2004.

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Last updated: 07/14/2016
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