Eric Lancaster

faculty photo
Assistant Professor of Neurology
Instructor of Neurology, The University of Pennsylvania
Department: Neurology

Contact information
3 W. Gates - Neurology
3400 Spruce St.
Philadelphia, PA 19104
Office: 215 349 5313
Fax: 215 349 5579
Lab: 215 898 0181
Graduate Group Affiliations
Education:
BS (Biomedical Engineering)
The Johns Hopkins University, 1994.
PhD (Neuroscience)
The University of Maryland, 2002.
MD (medicine)
The University of Maryland, 2003.
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Description of Research Expertise

Neuronal autoantibodies, encephalitis, acquired neuromyotonia (Isaacs' syndrome), peripheral nerve hyperexcitability, potassium channels, the glycine receptor, the GABA-B receptor, neuromuscular disorders, stiff person syndrome.

Description of Itmat Expertise

I am interested in autoimmunity to brain and peripheral nerve proteins. I treat patients with autoimmune disorders in my clinic and try to figure out how their autoimmune diseases work in my lab.

Selected Publications

Lancaster E and Evoli A.: Paraneoplastic disorders in thymoma patients. Journal of Thoracic Oncology. 9(9): S143-S147, Sep 2014.

Lancaster E, Leypoldt F, Titulaer MJ, Honnorat J, Waters PJ, Reindl M, Höftberger R.: Immunoglobulin G antibodies to the N-Methyl-D-aspartate receptor are distinct from immunoglobulin A and immunoglobulin M responses. Ann. Neurol. EPub ahead of print, Jul 2014 Notes: Letter to the editor.

Zhang C and Lancaster E. : Paraneoplastic cerebellar degeneration associated with non-cutaneous Merkel cell carcinoma. Neuroimmunology & Neuroinflammation. 1(2): e17, Jun 2014.

Greene M, Lai Y, Baella N, Dalmau J, and Lancaster E. : Antibodies to Delta/Notch-like Epidermal growth factor-related Receptor (DNER) in patients with anti-Tr, Paraneoplastic Cerebellar Degeneration, and Hodgkin’s Lymphoma. JAMA Neurology. Epub ahead of print, June 2014.

Farooqi MS, Lai Y, Lancaster E, Schmitt SE, and Sachais BS.: Therapeutic Plasma Exchange and Immunosuppressive Therapy in a Patient with Anti-GAD Antibody-Related Epilepsy: Quantification of the Antibody Response. Journal of Clinical Apheresis Epub ahead of print June 25., June. 2014.

King C, Lancaster E, Salomen D, Peles E, and Scherer SS.: Kv7.2 regulates the function of peripheral sensory neurons. Journal of Comparative Neurology. Journal of Comparative Neurology E pub ahead of print, March 2014.

Fleisher J, Richie M, Price R, Scherer SS, Dalmau J, Lancaster E.: Acquired neuromyotonia heralding recurrent thymoma in myasthenia gravis. JAMA Neurology. JAMA Neurology. 70(10): 1311-4, October 2013.

McKeon A, Martinez-Hernandez E, Lancaster E, Matsumoto JY, Harvey RJ, McEvoy KM, Pittock SJ, Lennon VA, Dalmau J. : Glycine Receptor Autoimmune Spectrum With Stiff-Man Syndrome Phenotype. Archives of Neurology Page: 1-9, October 2012 Notes: doi: 10.1001/jamaneurol.2013.574. [Epub ahead of print]

Lancaster E and Dalmau J.: Neuronal autoantigens – pathogenesis, associated disorders, and antibody testing. Nature Reviews Neurology 8(7): 380-90, June 2012.

Lancaster E, Martinez-Hernandez E, Titulaer MJ, Boulos M,
 Weaver S, Antoine J-C, Liebers E, Kornblum C,
 Bien CG, Honnorat J, Wong S, Xu J, Contractor A, Balice-Gordon R, and Dalmau J.: Antibodies to Metabotropic Glutamate Receptor 5 in the Ophelia 
syndrome. Neurology. 77(18): 1698-701, October 2011.

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Last updated: 01/02/2015
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