Michele Puszkarczuk Lambert

faculty photo
Assistant Professor of Pediatrics at the Children's Hospital of Philadelphia
Attending Physician, The Children's Hospital of Philadelphia
Attending Physician, Hospital of the University of Pennsylvania
Attending Physician, Pennsylvania Hospital
Assistant Director-Clinical Coagulation Laboratory, Departments of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
Division of Hematology
3615 Civic Center Blvd
ARC 316G
Philadelphia, PA 19083
Office: 215-590-4667
Fax: 267-426-5476
Lab: 215-590-1971
Education:
BS (Biology)
Rensselaer Polytechnic Institute, 1995.
MD (Medicine)
UMDNJ - New Jersey Medical School, 1999.
MTR
University of Pennsylvania, 2010.
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Description of Itmat Expertise

Platelet disorders in pediatric patients
Thrombocytopenia
ITP

Selected Publications

Neunert C, Despotovic J, Haley K, Lambert MP, Nottage K, Shimano K, Bennett C, Klaassen R, Stine K, Thompson A, Pastore Y, Brown T, Forbes PW, Grace RF: Thrombopoietin Receptor Agonist Use in Children: Data From the Pediatric ITP Consortium of North America ICON2 Study. Pediatric blood & cancer 63(8): 1407-13, Aug 2016.

Lambert MP, Kalish JM, Crowley BT, Schott A, Valverde K, Morissett J, Emanuel BS, Zackai EH, and McDonald-McGinn DM: : The Increased Prevalence of Malignancy in Twins with 22q11.2 Deletion Syndrome. 10th Biennial International 22q11.2 Conference, Sirmione, Italy. Platform Presentation, July 2016.

Lambert MP, Friedman D, Crowley BT, Jobes D, Zackai EH and McDonald-McGinn DM: The Frequency of Transfusion During Surgery for Congenital Heart Disease in Patients with 22q11.2 Deletion. 10th Biennial International 22q11.2 Conference, Simione, Italy. Platform Presentation, July 2016.

Simeoni I, Stephens JC, Hu F, Deevi SVV, Megy K, Bariana TK, Lentaigne C, Schulman S, Sivapalaratnam S, Vries MJA, Westbury SK, Greene D, Papadia S, Alessi M-C, Attwood AP, Ballmaier M, Baynam G, Bermejo E, Bertoli M, Bray PF, Bury L, Cattaneo M, Collins P, Daugherty LC, Favier R, French DL, Furie B, Gattens M, Germeshausen M, Ghevaert C, Goodeve AC, Guerrero JA, Hampshire DJ, Hart DP, Heemskerk JWM, Henskens YMC, Hill M, Hogg N, Jolley JD, Kahr WH, Kelly AM, Kerr R, Kostadima M, Kunishima S, Lambert MP, Liesner R, López JA, Mapeta RP, Mathias M, Millar CM, Nathwani A, Neerman-Arbez M, Nurden AT, Nurden P, Othman M, Peerlinck K, Perry DJ, Poudel P, Reitsma P, Rondina MT, Smethurst PA, Stevenson W, Szkotak A, Tuna S, van Geet Cl, Whitehorn D, Wilcox D, Zhang B, Revel-Vilk S, Gresele P, Bellissimo DB, Penkett CJ, Laffan MA, Mumford AD, Rendon A, Gomez K, Freson K, Ouwehand WH, Turro E: A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders. Blood 127(23): 2791-803, Jun 2016.

Grace RF, Despotovic JM, Bennett CM, Rothman JA, Lambert MP, Breakey VP, Bussel JB, Buchanan GR, Rose M, Geddis A, Shimano KA, Hege K, Haley K, Lorenzana A, Neunert CE, Thompson AA, Pastore YD, Jeng M, Stine K, Neier M, Neufeld EJ, Brown T, Forbes P, Klaassen RJ: Fatigue in Pediatric Immune Thrombocytopenia (ITP): Baseline Prevalence in Patients Starting Second Line Therapies in the First ITP Consortium of North America Research Study (ICON1). American Society of Pediatric Hematology/Oncology, Minneapolis, MN. Poster Presentation, May 2016.

Lambert MP, Kwiatkowski J: Iron Deficiency is a significant complication of Eltrombopag Treatment for ITP in Pediatric Patients Thrombosis and Hemostasis Societies of North America Meeting, Chicago, IL. Platform Presentation, April 2016.

Stritt S, Nurden P, Favier R, Favier M, Ferioli S, Gotru SK, van Eeuwijk JMM, Schulze H, Nurden AT, Lambert MP, Turro E, Burger-Stritt S, Matsushita Mi, Mittermeier L, Ballerini P, Zierler S, Laffan MA, Chubanov V, Gudermann T, Nieswandt B, Braun A: Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture. Nature communications 29(7): 11097, March 2016.

Romasko EJ, Devkota B, Jayaraman V, Jairam S, Scarano MI, Biswas S, Thom CS, Dulik MC, Conlin LK, Spinner NB, Krantz ID, Lambert MP: : Utility and Limitations of Exome Sequencing in the Diagnosis of Pediatric Platelet Disease Annual Clinical Genetics Meeting, Tampa, FL. Poster Presentation, March 2016.

Turro E, Greene D, Wijgaerts A, Thys C, Lentaigne C, Bariana TK, Westbury SK, Kelly AM, Selleslag D, Stephens JC, Papadia S, Simeoni I, Penkett C J, Ashford S, Attwood A, Austin S, Bakchoul T, Collins P, Deevi SVV, Favier R, Kostadima M, Lambert MP, Mathias M, Millar CM, Peerlinck K, Perry David J, Schulman S, Whitehorn D, Wittevrongel C De Maeyer M, Rendon A, Gomez K, Erber WN, Mumford AD, Nurden P, Stirrups K, Bradley JR, Lucy RF, Laffan MA, Van Geet C, Richardson S, Freson K, Ouwehand WH: A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies. Science translational medicine 8(328): 328ra30, Mar 2016.

Witmer CM, Lambert MP, O'Brien SH, Neunert CE: Multicenter Cohort Study Comparing U.S. Management of Inpatient Pediatric Immune Thrombocytopenia to Current Treatment Guidelines. Pediatric blood & cancer 63(7): epub, Feb 2016.

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Last updated: 07/21/2016
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