Leslie Raffini

faculty photo
Associate Professor of Pediatrics at the Children's Hospital of Philadelphia
Director, Hemostasis and Thrombosis Center, Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
The Children's Hospital of Philadelphia
Division of Hematology
3501 Civic Center Blvd
CTRB 11th Floor
Philadelphia, PA 19104
Office: 267 426-5029
B.S. (Molecular Biology)
University of Wisconsin, 1991.
University of Wisconsin, 1996.
M.S. (Clinical Epidemiology)
University of Pennsylvania, 2005.
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Description of Research Expertise

Risk Factors for Thromboembolic Events in Children

Description of Other Expertise

Diagnosis and Management of Bleeding Disorders in Children

Description of Itmat Expertise

Dr. Raffini's field of interest is clinical research in pediatric hemostasis and thrombosis.

Selected Publications

Glatz A, Keashen R, Chang J, Balsama L, Dori Y, Gillespie M, Giglia T, Raffini L, Rome J: Outcomes using a clinical practice pathway for the management of pulse loss following pediatric cardiac catheterization. Catheter Cardiovasc Interv 85(1): 111-7, 2015.

Law C and Raffini L: A guide to the use of anticoagulant drugs in children. Pediatr Drugs 2015.

Blevins E, Raffini L. : Extensive thrombotic complications after inferior vena cava filter placement in two pediatric patients with spinal cord injury: A cautionary tale and review. J Pediatr Hematol Oncol Sept 2014.

Leissinger C, Josephson C, Granger S, Konkle B, Kruse-Jarre R, Ragni M, Journeycake J, Valentino L, Key N, Gill J, McCrae K, Neufeld E, Manno C, Raffini L, Saxena K, Torres M, Marde V, Bennett C, Assmann S. : Rituximab for Treatment of Inhibitors in Hemophilia A: A Phase II Study. Thromb Haemost 112(3): 445-58, 2014.

Greene L, Law C, Jung M, Walton S, Ignjatovic V, Monagle P, Raffini L. : Lack of anti-Xa standardization results in significant low molecular weight heparin (enoxaparin) dose variation in neonates and children. J Thromb Haemost 12(9): 1554-7, 2014.

Stem J, Christensen A, Davis D, Raffini L: Safety of prophylactic anticoagulation at a pediatric hospital. J Pediatr Hematol Oncol 35(7): e287-91, 2013.

Ragni M, Fogarty P, Josephson N, Neff A, Raffini L, Kessler C.: Survey of current prophylaxis practice and bleeding characteristics of hemophilia children in U.S. Hemophilia Treatment Centers. Haemophilia 18(1): 63-68, 2012.

Raffini, L.: Thromboembolic events in Children Consultative Hemostasis and Thrombosis. Kitchen, C. (eds.). Elsevier Health Sciences, 2012.

Peutz J, Huang Y-S, Witmer C, Raffini L: Widespread use of fresh frozen plasma in U.S. Children's Hospitals despite limited evidence demonstrating a beneficial effect. J Pediatr 160(2): 210-215, 2012.

Raffini L, Trimarchi T, Beliveau J, Davis D: Thromboprophylaxis in a pediatric hospital: a patient safety and quality improvement initiative. Pediatrics 127: e1326-1332, 2011.

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Last updated: 05/01/2015
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