Leslie Raffini
Professor of Pediatrics (Hematology) at the Children's Hospital of Philadelphia
Director, Hemostasis and Thrombosis Center, Children's Hospital of Philadelphia, University of Pennsylvania
Department: Pediatrics
Contact information
Children's Hospital of Philadelphia
Division of Hematology
3501 Civic Center Blvd
CTRB 11th Floor
Philadelphia, PA 19104
Division of Hematology
3501 Civic Center Blvd
CTRB 11th Floor
Philadelphia, PA 19104
Office: 267 426-5029
Email:
raffini@email.chop.edu
raffini@email.chop.edu
Education:
B.S. (Molecular Biology)
University of Wisconsin, 1991.
M.D.
University of Wisconsin, 1996.
M.S.C.E (Clinical Epidemiology)
University of Pennsylvania, 2005.
B.S. (Molecular Biology)
University of Wisconsin, 1991.
M.D.
University of Wisconsin, 1996.
M.S.C.E (Clinical Epidemiology)
University of Pennsylvania, 2005.
Post-Graduate Training
Pediatric Resident, Johns Hopkins Hospital, 1996-1999.
Fellowship, Pediatric Hematology/Oncology, The Children's Hospital of Philadelphia, 1999-2002.
Permanent linkPediatric Resident, Johns Hopkins Hospital, 1996-1999.
Fellowship, Pediatric Hematology/Oncology, The Children's Hospital of Philadelphia, 1999-2002.
Description of Research Expertise
Risk Factors for Thromboembolic Events in ChildrenDescription of Other Expertise
Diagnosis and Management of Bleeding Disorders in ChildrenDescription of Itmat Expertise
Dr. Raffini's field of interest is clinical research in pediatric hemostasis and thrombosis.Selected Publications
Dain A.S., Whitworth H., Raffini L: Letter to the editor in response to “Coagulation abnormalities and clinical complications in children with SARs-CoV-2: A systematic review of 48,322 patients” J Pediatr Hematol Oncol 45(1): 44-45, 2023.Whitworth H., Amankwah E., Betensky M., Castellucci L., Cuker A., Goldenberg N., Male C., Rinzler E., Zia A., Raffini L: Updated guidance for efficacy and safety outcomes for clinical trials in venous thromboembolism in children: Communication from the ISTH SSC Subcommittee on Pediatric and Neonatal Thrombosis and Hemostasis. J Thromb Haemost epub ahead of print 2023.
Barnes G., Ageno W., Castellucci L., Chiasakul T., Eslick R., Gailani D., Raffini L., Rzende S., Weitz J., Cuker A. : Recommendation on the nomenclature for oral anticoagulants: Updated guidance from the SSC of the ISTH. J Thromb Haemost epub ahead of print 2023.
Monagle P., Male C., Raffini L: The value of the old and the new; a commentary regarding the need to update the 2018 ASH Guidelines for the management of pediatric venous thromboembolism. Blood Adv epub ahead of print 2023.
Whitworth, H., Clark H., Hubbard R., Witmer C., Leonard C., Raffini L.: High rate of recurrent venous thromboembolism in children and adolescents with unprovoked venous thromboembolism. J Thromb Haem 21(1): 47-56, 2023.
Whitworth H., Beslow L., Hubbard R., Leonard C., Scobell R., Witmer C., Raffini L.: Outcomes in infants with unprovoked venous thromboembolis. Res Pract Thrombosis Haemost in press, 2023.
Ragni M., Young G., Batsuli G., Bisson E., Carpenter S., Croteau S., Cuker A., Curtis R., Denne M., Ewenstein B., Federizo A., Frick N., Funkhouser K., George L., Hoots K., Jobe S., Krava E., Landmead C., Lewis R., Lopez J., Malec L., Mann Z., Neely E., Neufeld E., Pierce G., Pipe S., Pitler L., Raffini L., Schnur L, Shavit J. : Building the foundation for a community-generated national research blueprint for inherited bleeding disorders. Facilitating research through infrastructure, workforce, and resources and funding Expert Rev Hematologist 16: 107-27, 2023.
O’Brien S., Stanek J., Witmer C. Raffini L.: The continued rise of venous thromboembolism across U.S. Children’s Hospitals. Pediatrics in press, 2022.
Barnes G., Burnett A., Allen A., Ansell J., Blumenstein M., Clark N., Crowther M., Dager W. Deitelzweig S., Ellsworth S., Garcia D., Kaatz S., Raffini L., Rajasekhar A., VanBeek A., Minichiello T.: Thromboembolic prevention and anticoagulant therapy during the COVID-19 pandemic: updated clinical guidance from the anticoagulation forum. J Thromb Thrombolysis 54(2): 197-22, 2022.
Whitworth H., Raffini L: Practical considerations for use of direct oral anticoagulants in children. Front Pediatr 10: e860369, 2022.