David F. Dinges

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Professor of Psychology in Psychiatry
Member, David Mahoney Institute of Neurological Sciences
Associate Director and Member, Center for Sleep and Respiratory Neurobiology
Associate Director, Center for Sleep and Circadian Neurobiology, University of Pennsylvania School of Medicine.
Director, Unit for Experimental Psychiatry, University of Pennsylvania School of Medicine.
Chief, Division of Sleep and Chronobiology, Department of Psychiatry, University of Pennsylvania School of Medicine.
Member, Biological Basis of Behavior Program
Member, Committee on Appointments and Promotions, University of Pennsylvania School of Medicine
Chair, Translation Research Center (TRC) Advisory Committee, Hospital of the University of Pennsylvania School of Medicine
Member, Institute for Translational Medicine and Therapeutics
Member, Budget Subcommittee, Clinical Translation Research Center (CTRC), Hospital of the University of Pennsylvania School of Medicine
Member, Center for Functional Neuroimaging
Affiliated Member, Center for Cognitive Neuroscience
Core Member, Penn Genomics Frontiers Institute
Member,, Penn Comprehensive Neuroscience Center
Vice Chair for Faculty Affairs and Professional Development, Department of Psychiatry, University of Pennsylvania School of Medicine
Vice Chair for Faculty Affairs and Professional Development, University of Pennsylvania Perelman School of Medicine, Department of Psychiatry
Senior Fellow, Center for Health Behavior Research
Department: Psychiatry

Contact information
Chief, Division of Sleep and Chronobiology
Director, Unit for Experimental Psychiatry
Department of Psychiatry
University of Pennsylvania School of Medicine
1013 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104-6021
Office: 215-898-9949
Fax: 215-573-6410
A.B. (Psychology)
Saint Benedict's College, Honors, 1971.
M.S. (Physiological Psychology)
Saint Louis University, 1974.

Washington University, Central Institute for the Deaf, 1975.
Ph.D. (Physiological Psychology)
Saint Louis University, 1976.
M.A. (Honorary)
University of Pennsylvania , 1993.
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Description of Research Expertise

Sleep; chronobiology; human neurobehavioral functions; cognitive performance; psychophysiological asssessment

Description of Other Expertise

human behavior and performance functioning in space flight

Description of Itmat Expertise

Dr. Dinges conducts studies on human sleep-wake states, circadian pacemaker assessment, neurobehavioral, neuroendocrine and neuroimmune functions, physiological alertness, attention and cognitive functions, sleepiness and fatigue, and EEG power spectral analyses, functional neuroimaging, and the genomics of differential vulnerability to sleep deprivation.

Selected Publications

Prasad, B., Usmani, S., Steffen, A.D., Van Dongen, H., Pack, F.M., Strakovsky, I., Staley, B., Dinges, D., Maislin, G., Pack, A.I., Weaver, T.E. : Short-Term Variability in Apnea-Hypopnea Index During Extended Home Portable Monitoring. Journal of Clinical Sleep Medicine February 2016.

. Mullington, J.M., Abbott, S.M., Carroll, J.E., Dijk, D-J., Dinges, D.F., Gehrman, P.R., Ginsburg, G.S., Gozal, D., Haack, M., Lim, D.C., Macrea, M., Pack, A.I., Plante, D.T., Teske, J.A., Zee, P: Developing biomarker arrays predicting sleep and circadian-coupled risks to health. SLEEP 39(4): 727-736, 2016.

Creber, R.M., Pak, V.M., Varesse, M., Dinges, D.F., Wald, J., Riegel, B. : Determinants of behavioral alertness in adults with heart failure. Journal of Clinical Sleep Medicine December 2015.

Weljie, A.M., Meer, P., Goel, M., Sengupta, A., Kayser, M.S., Abel, T. Birnbaum, M.J., Dinges, D.F., Sehgal, A.M: Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt. Proceedings of the National Academies of Sciences of the USA. PNAS Early Edition 112(8): 2569-2574, January 2015.

Fang, Z., Zhu, S., Hu, S., Ma, N., Shi, H., Goel, N., Detre, J.A., Dinges, D.F., Rao, H.: Disruption and recovery of spontaneous brain connectivity and memory following sleep deprivation. Scientific Reports 5, 2015.

Basner, M., Savitt, A., Moore, T.M., Port, A.M., McGuire, S., Ecker, A.J., Nasrini, J., Mollicone, D.J., Mott, C.M., McCann, T., Dinges, D.F., Gur R.C.: Development and Validation of the Cognition Test Battery for Spaceflight. Aerospace Medicine and Human Performance 86(11): 942-952, 2015.

Lerchl, K., Rakova, N., Dahlmann, A., Rauh, M., Goller, U., Basner, M., Dinges, D.F., Beck, L., Agureev, A., Larina, I., Baranov, V., Morukov, B., Eckardt, K.U., Vassilieva, G., Wabel, P., Vienken, J., Kirsch, K., Johannes, B,., Krannich, B., Luft, F.C., Titze, J. : Agreement between 24-hour salt ingestion and sodium excretion in a controlled environment. Hypertension 66(4): 850-857, 2015.

Spaeth, A.M., Dinges, D.F., Goel, N: Phenotypic vulnerability of energy balance responses to sleep loss in healthy adults. Scientific Reports 5: 14920, 2015.

Ma, N., Dinges, D.F., Basner, M., Rao H: How acute total sleep loss affects the attending brain: A meta-analysis of neuroimaging studies. SLEEP 38(2), 2015.

Goel, G., Basner, M., Dinges, D.F.: Phenotyping of neurobehavioral vulnerability to circadian phase during sleep loss. Chapter 13, Methods in Enzymology 552: 285-308, 2015.

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Last updated: 04/19/2016
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