Steven J. Siegel

faculty photo
Professor of Psychiatry
Department: Psychiatry

Contact information
Rm 2202
125 S. 31st street
Translational Research Building
Philadelphia, PA 19104-4283
Office: 215 573 0278
Graduate Group Affiliations
B.A. (Neuroscience)
Colgate University, 1986.
Ph.D. (Neurobiology)
Mount Sinai School of Medicine, 1994.
Medicine Mount Sinai School of Medicine, 1996.
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Description of Itmat Expertise

Dr. Siegel is interested in the design and development of surgically implantable long-term delivery systems for the treatment of schizophrenia and other major neuropsychiatry conditions. His laboratory also develops and validates animal models of schizophreenia and Autism to foster better understanding of the disorders and their treatment.

Selected Publications

Amann, L. C., Halene, T. B., Ehrlichman, R. S., Luminais, S. N., Ma, N., Abel, T., Siegel, S. J.: Chronic ketamine impairs fear conditioning and produces long-lasting reductions in auditory evoked potentials. 35(2): 311-7, 2009.

Pierce, M., Marbury, T., O'Neill, C., Siegel, S., Du, W., Sebree, T.: Zelrix: a novel transdermal formulation of sumatriptan. Headache 49(6): 817-25, 2009.

Patterson, F., Jepson, C., Strasser, A. A., Loughead, J., Perkins, K. A., Gur, R. C., Frey, J. M., Siegel, S., Lerman, C.: Varenicline improves mood and cognition during smoking abstinence. Biol Psychiatry 65(2): 144-9, 2009.

Patterson, F., Jepson, C., Loughead, J., Perkins, K., Strasser, A. A., Siegel, S., Frey, J., Gur, R., Lerman, C.: Working memory deficits predict short-term smoking resumption following brief abstinence. 2009.

Lazarewicz, M. T., Ehrlichman, R. S., Maxwell, C. R., Gandal, M. J., Finkel, L. H., Siegel, S. J.: Ketamine Modulates Theta and Gamma Oscillations. J Cogn Neurosci 2009.

Halene, T. B., Talmud, J., Jonak, G. J., Schneider, F., Siegel, S. J.: Predator odor modulates auditory event-related potentials in mice. Neuroreport 2009.

Halene, T. B., Ehrlichman, R. S., Liang, Y., Christian, E. P., Jonak, G. J., Gur, T. L., Blendy, J. A., Dow, H. C., Brodkin, E. S., Schneider, F., Gur, R. C., Siegel, S. J.: Assessment of NMDA receptor NR1 subunit hypofunction in mice as a model for schizophrenia. Genes Brain Behav 2009.

Ehrlichman, R. S., Luminais, S. N., White, S. L., Rudnick, N. D., Ma, N., Dow, H. C., Kreibich, A. S., Abel, T., Brodkin, E. S., Hahn, C. G., Siegel, S. J.: Neuregulin 1 transgenic mice display reduced mismatch negativity, contextual fear conditioning and social interactions. Brain Res 2009.

Ehrlichman, R. S., Gandal, M. J., Maxwell, C. R., Lazarewicz, M. T., Finkel, L. H., Contreras, D., Turetsky, B. I., Siegel, S. J.: N-methyl-d-aspartic acid receptor antagonist-induced frequency oscillations in mice recreate pattern of electrophysiological deficits in schizophrenia. Neuroscience 158(2): 705-12, 2009.

Bodarky, C. L., Halene, T. B., Ehrlichman, R. S., Banerjee, A., Ray, R., Hahn, C. G., Jonak, G., Siegel, S. J.: Novel Environment and GABA Agonists Alter ERPs in NMDA NR1 Hypomorphic and Wild-type Mice. J Pharmacol Exp Ther 2009.

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Last updated: 07/24/2012
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