Steven Brem

faculty photo
Professor of Neurosurgery at the Hospital of the University of Pennsylvania
Chair, Neuro-TCE, Hospital of the University of Pennsylvania
Chief, Neurosurgical Oncology, Hospital of the University of Pennsylvania
Co-Director, Brain Tumor Center, Hospital of the University of Pennsylvania
Program Leader, Neuro-Onc Service Line, Abramson Cancer Center at the Hospital of the University of Pennsylvania
Department: Neurosurgery

Contact information
3400 Spruce Street, 3rd Floor Silverstein
Department of Neurosurgery
Philadelphia, PA 19104
Office: (215) 662-3487
Education:
BA (Magna Cum Laude)
Rutgers University, 1968.
MD (Medicine - Cum Laude)
Harvard Medical School, 1972.
Permanent link
 

Description of Itmat Expertise

Experimental therapeutics, brain tumors, angiogenesis, tumor invasion, genomics, clinical trials, radiosurgery, brain mapping, connectomics,

Description of Research Expertise

Angiogenesis, Neuro-Oncology, Translational Drug Discovery, Personalized Medicine, Genomics, Biomarkers, Experimental Therapeutics, Brain Mapping, Health Outcomes, Brain Metastases, Clinical Guidelines, Clinical Pathways, Glioma Invasion, Targeted Brain Tumor Therapies

Selected Publications

Prateek Agarwal, Arka N. Mallela, Nicholas Goel, Joseph Durgin, Donald M. O’Rourke, Kalil G. Abdullah, Steven Brem: Factors Associated with Ventriculoperitoneal Shunt Dependency Following Glioblastoma Resection. Proceedings of AANS 2018.

Ahmed FI, Abdullah KG, Durgin J, Jayaram M, Biggiani G, O’Rourke DM, Brem S: Evaluating the Association Between Extent of Resection and Survival in Gliosarcoma. Proceedings of AANS 2018.

Snyder KJG, Ahmed FI, Brem S, Abdullah KG: Use of decision analytics modeling to assist in neurosurgical decision making: a feasibility study in elderly patients undergoing glioblastoma resection versus biopsy. Proceedings of AANS 2018.

Kalil G. Abdullah1, Nicholas J. Goel1, Prateek Agarwal1, Arka N. Mallela, Eileen Maloney Wilensky, Donald M. O’Rourke, Steven Brem: Factors associated with increased survival in patients undergoing 3 or more resections of recurrent glioblastoma. Proceedings of AANS 2018.

Kalil G. Abdullah, Nicholas J. Goel, Prateek Agarwal, Arka N. Mallela, Eileen Maloney Wilensky, Donald M. O’Rourke, Steven Brem: Factors associated with increased survival in patients undergoing 3 or more resections of recurrent glioblastoma. Proceedings of AANS 2018.

Ahmed FI, Durgin J, Agarwal P, MacFawn, O, Barrow M, O’Rourke DM, Abdullah KG , Brem S: Quantifying Extent of Resection Thresholds for Increased Survival in Elderly Patients with Glioblastoma. Proceedings of AANS 2018.

O'Rourke DM, Nasrallah MP, Desai A, Melenhorst JJ, Mansfield K, Morrissette JJD, Martinez-Lage M, Brem S, Maloney E, Shen A, Isaacs R, Mohan S, Plesa G, Lacey SF, Navenot JM, Zheng Z, Levine BL, Okada H, June CH, Brogdon JL, Maus MV.: A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma. Science Translational Medicine 9(399), Jul 2017.

Thawani Jayesh P, Singh Nickpreet, Pisapia Jared M, Abdullah Kalil G, Parker Drew, Pukenas Bryan A, Zager Eric L, Verma Ragini, Brem Steven: Three-Dimensional Printed Modeling of Diffuse Low-Grade Gliomas and Associated White Matter Tract Anatomy. Neurosurgery 80(4): 635-645, Apr 2017.

Spaethling Jennifer M, Na Young-Ji, Lee Jaehee, Ulyanova Alexandra V, Baltuch Gordon H, Bell Thomas J, Brem Steven, Chen H Isaac, Dueck Hannah, Fisher Stephen A, Garcia Marcela P, Khaladkar Mugdha, Kung David K, Lucas Timothy H, O'Rourke Donald M, Stefanik Derek, Wang Jinhui, Wolf John A, Bartfai Tamas, Grady M Sean, Sul Jai-Yoon, Kim Junhyong, Eberwine James H: Primary Cell Culture of Live Neurosurgically Resected Aged Adult Human Brain Cells and Single Cell Transcriptomics. Cell reports 18(3): 791-803, Jan 2017.

Strickland-Marmol Leah B, Brem Steven, Rojiani Amyn M, Rojiani Mumtaz V: Vessel morphometric parameters-correlation with histologic grade and VEGF expression in oligodendroglioma. American journal of cancer research 7(4): 973-981, 2017.

back to top
Last updated: 11/02/2017
The Trustees of the University of Pennsylvania