Steven Brem

faculty photo
Professor of Neurosurgery at the Hospital of the University of Pennsylvania
Department: Neurosurgery

Contact information
3400 Spruce Street, 3rd Floor Silverstein
Department of Neurosurgery
Philadelphia, PA 19104
Office: (215) 662-7854
BA (Magna Cum Laude)
Rutgers University, 1968.
MD (Medicine - Cum Laude)
Harvard Medical School, 1972.
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Description of Itmat Expertise

Experimental therapeutics, brain tumors, angiogenesis, tumor invasion, genomics, clinical trials, radiosurgery, brain mapping, connectomics,

Description of Research Expertise

Angiogenesis, Neuro-Oncology, Translational Drug Discovery, Personalized Medicine, Genomics, Biomarkers, Experimental Therapeutics, Brain Mapping, Health Outcomes, Brain Metastases, Clinical Guidelines, Clinical Pathways, Glioma Invasion, Targeted Brain Tumor Therapies

Selected Publications

Coppola Domenico, Balducci Lodovico, Chen Dung-Tsa, Loboda Andrey, Nebozhyn Michael, Staller Aileen, Fulp William J, Dalton William, Yeatman Timothy, Brem Steven: Senescence-Associated-Gene signature identifies genes linked to age, prognosis, and progression of human gliomas. Journal of geriatric oncology Sep 2014.

Rosenfeld Myrna R, Ye Xiaobu, Supko Jeffrey G, Desideri Serena, Grossman Stuart A, Brem Steven, Mikkelson Tom, Wang Daniel, Chang Yunyoung C, Hu Janice, McAfee Quentin, Fisher Joy, Troxel Andrea B, Piao Shengfu, Heitjan Daniel F, Tan Kay-See, Pontiggia Laura, O'Dwyer Peter J, Davis Lisa E, Amaravadi Ravi K: A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme. Autophagy 10(8): 1359-68, Aug 2014.

Brem Steven, Meyers Christina A, Palmer Gary, Booth-Jones Margaret, Jain Surbhi, Ewend Matthew G: Preservation of neurocognitive function and local control of 1 to 3 brain metastases treated with surgery and carmustine wafers. Cancer 119(21): 3830-8, Nov 2013.

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Last updated: 09/30/2014
The Trustees of the University of Pennsylvania