Timothy H Lucas

faculty photo
Assistant Professor of Neurosurgery
Director, Translational Neuromodulation Laboratory, Department of Neurosurgery, University of Pennsylvania
Associate Director, Center for Neuroengineering & Therapeutics, University of Pennsylvania
Director, Neurosurgery Gene Therapy Program, University of Pennsylvania
Director, Laser Neurosurgery Center, University of Pennsylvania
Mack Technology Fellow, Wharton Business School, University of Pennsylvania
Department: Neurosurgery

Contact information
3400 Spruce Street
3rd Floor Silverstein
Philadelphia, PA 19104
Office: 215-615-0578
Fax: 215-349-5534
Lab: 215-746-1336
Graduate Group Affiliations
B.S. (Neurobiological Sciences & Psychobiology)
University of Florida, 1996.
M.D. (Medicine)
University of Florida, 2001.
Ph.D. (Physiology & Biophysics)
University of Washington, 2009.
MCHI (Health Care Innovation, Public Health and Health Policy)
University of Pennsylvania, 2019.
Permanent link

Description of Itmat Expertise

Translational neuromodulation,
Brain-computer interface,
Motor systems neuroprosthesis,
Sensory systems neuroprosthesis,
Voluntary movement,
Implantable computer systems

Description of Research Expertise

Brain-machine interface / Brain-computer interface
Motor Cortex Functional Organization
Voluntary Movement
Speech and Language Organization
Cortical Plasticity
Basal Ganglia - Cortical Interactions
Cortical/Basal Ganglia Stimulation
Cortical Spike and Local Field Recording
Basal Ganglia Spike and Local Field Recording
Spinal Cord Stimulation and Mapping

Selected Publications

Chen H and TH Lucas: Advances in DBS surgery. Advances in Functional Neurosurgery, Thieme. Anderson, W (eds.). Thieme, 1(1), 6 2018.

Liu X, H Zhu, M Zhang, AG Richardson, SY Sritharan, D Ge, Y Shu, TH Lucas, J Van der Spiegel: A fully integrated wireless sensor brain interface system to restore finger sensation. International symposium on circuits and systems 1, 5 2017.

Abdullah KG, Y Li, N Nayak, J Thawani, R Balu, TH Lucas: Long term utility and complication profile of open craniotomy for biopsy in patients with idiopathic encephalitis. J Clinical Neuroscience 37, 2017.

Liu X, M Zhang, M Honzhu, A Richardson, TH Lucas, J Van der Spiegel: Design of a closed-loop, bi-directional brain machine interface system with energy efficient neural feature extraction and PID control. IEEE Trans Biomed Circuits and Systems 11(4), 2017.

Richardson AG and TH Lucas: Brainstem neural interfaces for long term subcortical neuromodulation. Frontiers in Neuroscience in press, 2017.

Mallela A, K Abdullah, AG Richardson, TH Lucas: Subgaleal topical vancomycin reduces surgical site infections following craniotomy: an examination of over 350 surgeries at an academic medical center. Neurosurgery in press, 2017.

Ung H, B Litt, A Nanivadekar, C Cazares, L Kini, J Wagenaar, D Becker, M Kahana, TH Lucas, G Baltuch, M Sperling, A Sharan, K Davis: Spatial distribution of epileptiform spikes impacts visual word memory encoding. Brain 140(8), 2017.

Lucas TH, X Liu, M Zhang, S Sritharan, I Planell, Y Ghenbot, S Torres, C Brandon, J Van der Spiegel, AG Richardson: Strategies for autonomous sensor-brain interfaces for closed loop sensory reanimation of paralyzed limbs. Neurosurgery 64, 2017.

Spaethling J, YJ Na, J Lee, A Ulyanova, GH Baltuch, TJ Bell, S Brem, HI Chen, H Dueck, SA Fisher, M Garcia, M Khaladkar, DK Kung, TH Lucas, MD O'Rourke, D Stephnik, J Wank, JA Wolfe, T Bartfai, MS Grady, JY Sul, J Kim, JH Eberwine: Primary cell culture of live neurosurgical resected aged adult human brain cells and single cell transcriptomics. Cell Reports 18(3), 2017.

Ezzyat Y, JF Burke, DF Levy, A Lyalenko, MR Sperling, AD Sharan, GA Worrell, MT Kucewicz, BC Jobst, KA Davis, TH Lucas, RE Gross, BC Lega, JM Stein, S Das, R Gorniak, DS Rizzuto, MJ Kahana: Targeted brain stimulation to modulate memory performance in humans. Current Biology 27: 1251-8, 2017.

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Last updated: 12/13/2017
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