Chyke A Doubeni

faculty photo
Associate Professor of Family Medicine and Community Health
Full member, Abramson Cancer Center
Senior Fellow, Leonard Davis Institute of Health Economics
Senior Fellow, Center for Public Health Initiatives
Senior Scholar, Center for Clinical Epidemiology and Biostatistics
Member, Penn Program on Race Science and Society
Board member, Clinical Practices of the University of Pennsylvania Board of Directors
Chair, Department of Family Medicine and Community Health, University of Pennsylvania Perelman School of Medicine
Board member, Hospital of the University of Pennsylvania Medical Board of Directors
Member, The Institute for Translational Medicine and Therapeutics
Department: Family Medicine and Community Health

Contact information
Department of Family Medicine and Community Health
Perelman School of Medicine
University of Pennsylvania
PPMC - Andrew Mutch Building, #720
51 N. 39th Street
Philadelphia, PA 19104
Office: 2156628881
MD (MBBS) (Bachelor of Medicine & Bachelor of Surgery)
College of Medicine, University of Lagos, Nigeria, 1987.
F.R.C.S. (Fellow)
Royal College of Surgeons of England, UK, 1993.
M.P.H. (Public Health)
University of Massachusetts Amherst, MA , 2004.
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Description of Itmat Expertise

colorectal cancer screening and prevention

Description of Other Expertise

Dr. Doubeni currently serves as the Chair for the Department of Family Medicine and Community Health at the Perelman School of Medicine of the University of Pennsylvania (Penn). He is a Senior Scholar in the Penn Center for Clinical Epidemiology and Biostatistics, and a Senior Fellow in both the Leonard Davis Institute of Health Economics and the Center for Public Health Initiatives. Dr. Doubeni serves as diversity search advisor for the Department of Family Medicine and Community Health. He had also served as interim Associate Vice Provost for Diversity (AVPD) for the UMASS Medical School, supporting the recruitment, retention and career advancement of faculty that are underrepresented in academic medicine by building external collaborative relationships.

Description of Research Expertise

Dr. Doubeni's research is on colorectal cancer focusing on racial and socioeconomic disparities in mortality and on the effectiveness of screening. He currently leads National Institute of Health-funded multisite studies of the comparative effectiveness colorectal cancer screening and is a co-principal investigator of one of three colorectal cancer research centers of the PROSPR (Population-Based Research Optimizing Screening through Personalized Regimens) network. The PROSPR center, based in Kaiser Permanente in Northern and Southern California, is examining critical questions about factors that limit the optimal performance or effectiveness of colorectal cancer screening (with colonoscopy or fecal immunochemical test) in order to remediate avoidable failures in the process of screening. Dr. Doubeni received a 2010 Presidential Early Career Award for Scientists and Engineers (PECASE) for his work on cancer screening comparative effectiveness research, mentoring and community service.

Selected Publications

Doubeni CA, Weinmann S, Adams K, Kamineni A,Buist DSM, Ash AS, Rutter CM, Doria-Rose VP, Corley DA, Greenlee RT, Chubak J, Williams A, Kroll-Desrosiers AR, Johnson E, Webster J, Richert-Boe K, Levin TR, Fletcher RH, Weiss NS: Screening colonoscopy and risk of incident late-stage colorectal cancer diagnosis in average-risk adults: a nested case-control study. Annals of Internal Medicine 158(5_0_1): 312-320, March 2013 Notes: Ann Intern Med 5 March 2013: Vol. 158, No. 158, pp. 312-320.

Doubeni CA, Major JM, Laiyemo AO, Schootman M, Zauber AG, Hollenbeck A, Sinha R, Allison J: Contribution of Behavioral Risk Factors and Obesity to Socioeconomic Differences in Colorectal Cancer Incidence. J National Cancer Inst. Oxford University Press, 104(18): 1353-62, Sep 2012 Notes: Published online September 5, 2012; 10.1093/jnci/djs346.

Doubeni CA, Schootman M, Major JM, TorresStone RA, Laiyemo AO, Park Y, Lian M, Messer L, Graubard BI, Sinha R, Hollenbeck AR, Schatzkin A: Health status, neighborhood socioeconomic context, and premature mortality in the United States: The National Institutes of Health-AARP Diet and Health Study. American Journal of Public Health 102(4): 680-8, Apr 2012 Notes: doi:10.2105/AJPH.2011.300158.

Doubeni CA, Corley DA, Fletcher RH, Field TS, Gunter M.: The impact of eliminating cost barriers on socioeconomic disparities in colorectal cancer screening. International Cancer Screening Network, Australia October 2012 Notes: poster presentation.

Laiyemo AO, Doubeni CA, Badurdeen DS, Murphy G, Marcus PM, Schoen RE, Lanza E, Smoot DT, Cross, AJ: Obesity, weight change, and risk of adenoma recurrence: a prospective trial. Endoscopy 44(9): 813-8, Sep 2012 Notes: Epub 2012 Aug 27.

Buist D, Tuzzio L, Greenlee R, Field T, Williams A, Weinmann S, Stout N, Kamineni A, Doubeni C: PS1-33: Cancer Screening Guideline Development, Implementation and Dissemination: Connection Points for Researchers and Health Care Delivery Systems for Comparative Effectiveness Research. Clin Med Res. Marchfield Clinic, 10(3): 157, Aug 2012 Notes: HMORN 2012 Conference: Comparative Effectiveness Research poster presentation

Major JM, Oliver NM, Doubeni CA, Hollenbeck AR, Graubard BI, Sinha R: Socioeconomic status, healthcare density, and risk of prostate cancer among African American and Caucasian men in a large prospective study. Cancer causes & control: CCC 23(7): 1185-91, Jul 2012.

Doubeni CA, Laiyemo AO, Major JM, Schootman M, Lian M, Park Y, Graubard BI, Hollenbeck A, Sinha R: Socioeconomic status and the risk of colorectal cancer: an analysis of over one-half million adults in the NIH-AARP Diet and Health Study. Cancer. American Cancer Society, 118(14): 3636-44, Jul 2012 Notes: Article first published online: 3 Jan 2012 DOI: 10.1002/cncr.26677.

Doubeni CA, Jambaulikar GD, Fouayzi H, Robinson SB, Gunter MJ, Field TS, Roblin DW, Fletcher RH: Neighborhood socioeconomic status and use of colonoscopy in an insured population--a retrospective cohort study. PloS one 7(5): e36392, May 2012 Notes: DOI: 10.1371/journal.pone.0036392

Field TS, Buist DS, Doubeni CA, Enger S, Fouayzi H, Hart G, Korner EJ, Lamerato L, Bachman DJ, Ellis J, Herrinton L, Hornbrook MC, Krajenta R, Liu L, Yao J : Disparities and survival among breast cancer patients. J Natl Cancer Inst Monogr. Oxford University Press, 2005(35): 88-95, 2005 Notes: DOI: 10.1093/jncimonographs/lgi044

Lian M, Schootman M, Doubeni CA, Park Y, Major JM, Stone RA, Laiyemo AO, Hollenbeck AR, Graubard BI, Schatzkin A: Geographic variation in colorectal cancer survival and the role of small-area socioeconomic deprivation: a multilevel survival analysis of the NIH-AARP Diet and Health Study Cohort. Am J Epidemiol 174(7): 828-38, October 2011 Notes: Epub 2011 Aug 11.

Laiyemo AO, Doubeni CA, Pinsky PF, Doria-Rose VP, Sanderson AK 2nd, Bresalier R, Weissfeld J, Schoen RE, Marcus PM, Prorok PC, Berg CD: Factors associated with inadequate colorectal cancer screening with flexible sigmoidoscopy. Cancer Epidemiol 36(4): 395-99, Aug 2012 Notes: doi: 10.1016/j.canep.2011.10.013. Epub 2011 Nov 22.

Laiyemo AO, Doubeni CA, Sanderson AK 2nd, Pinsky PF, Badurdeen DS, Doria-Rose VP, Marcus PM, Schoen RE, Lanza E, Schatzkin A, Cross AJ: Likelihood of missed and recurrent adenomas in the proximal versus the distal colon. Gastrointest Endosc 74(2): 253-61, August 2011 Notes: Epub 2011 May 6.

Laiyemo AO, Doubeni C, Pinsky PF, Doria-Rose VP, Bresalier R, Lamerato LE, Crawford ED, Kvale P, Fouad M, Hickey T, Riley T, Weissfeld J, Schoen RE, Marcus PM, Prorok PC, Berg CD : Race and colorectal cancer disparities: health-care utilization vs different cancer susceptibilities. J Natl Cancer Inst 102(8): 538-46, Apr 2010 Notes: Showed that disparities in colorectal cancer were the result of differences in health care utilization and no biological differences in lesions was discernible.

Briesacher, BA, Tjia J, Doubeni CA, Chen Y, Rao SR: Methodological issues in using multiple years of the medicare current beneficiary survey. Medicare Care & Medicaid Research Review 2(1): E1-E20, Feb 2012 Notes: DOI: 10.5600/mmrr.002.01.a04

Higgins AY, Doubeni AR, Phillips KL, Laiyemo AO, Briesacher B, Tjia J, Doubeni CA: Self-reported colorectal cancer screening of Medicare beneficiaries in family medicine vs. internal medicine practices in the United States: a cross-sectional study. BMC Gastroenterology 12(23), March 2012 Notes: Online only DOI: 10.1186/1471-230X-12-23.

Major JM, Cross AJ, Doubeni CA, Park Y, Lian M, Hollenbeck AR, Schatzkin A, Graubard BI, Sinha R: Socioeconomic deprivation impact on meat intake and mortality: NIH-AARP Diet and Health Study. Cancer causes & control : CCC 22(12): 1699-1707, Dec 2011 Notes: Epub 2011 Oct 5.

Major JM, Doubeni CA, Freedman ND, Park Y, Lian M, Hollenbeck AR, Schatzkin A, Graubard BI, Sinha R: Neighborhood socioeconomic deprivation and mortality: NIH-AARP Diet and Health Study. PloS one 5(11): e15538, Nov 2010 Notes: DOI: 10.1371/journal.pone.0015538

Doubeni CA, Laiyemo AO, Young AC, Klabunde CN, Reed G, Field TS, Fletcher RH: Primary care, economic barriers to health care, and use of colorectal cancer screening tests among Medicare enrollees over time. Annals of Family Medicine 8(4): 299-307, Jul-Aug 2010 Notes: doi:10.1370/afm.1112.

Doubeni CA, Reed G, Difranza JR: Early course of nicotine dependence in adolescent smokers. Pediatrics 125(6): 1127-33, Jun 2010 Notes: Epub 2010 May 3.

Doubeni CA, Laiyemo AO, Klabunde CN, Young AC, Field TS, Fletcher RH: Racial and ethnic trends of colorectal cancer screening among Medicare enrollees. American Journal of Preventive Medicine 38(2): 184-91, Feb 2010 Notes: doi: 10.1016/j.amepre.2009.10.037

Doubeni CA, Laiyemo A O, Reed G, Field TS, Fletcher RH: Socioeconomic and racial patterns of colorectal cancer screening among Medicare enrollees in 2000 to 2005. Cancer Epidemiol Biomarkers Prev 18(8): 2170-5, Aug 2009 Notes: doi: 10.1158/1055-9965.EPI-09-0104. Epub 2009 Jul 21.

Doubeni CA, Li W, Fouayzi H, DiFranza JR: Perceived accessibility of cigarettes among youth: a prospective cohort study. American Journal of Preventive Medicine 36(3): 239-42, Mar 2009 Notes: doi:10.1016/j.amepre.2008.11.006.

Doubeni CA, Li W, Fouayzi H, Difranza JR: Perceived accessibility as a predictor of youth smoking. Annals of Family Medicine 6(4): 323-30, Jul-Aug 2008 Notes: doi: 10.1370/afm.841.

Doubeni CA, Field TS, Buist DSM, Korner EJ, Bigelow C, Lamerato L, Herrinton L, Quinn VP, Hart G, Hornbrook Mark C, Gurwitz Jerry H, Wagner EH: Racial differences in tumor stage and survival for colorectal cancer in an insured population. Cancer 109(3): 612-20, Feb 2007.

Spencer FA, Lessard D, Doubeni CA, Yarzebski J, Gore JM, Goldberg RJ: Treatment practices and outcomes of patients with established peripheral arterial disease hospitalized with acute myocardial infarction in a community setting. American Heart Journal 153(1): 140-6, Jan 2007.

Doubeni CA, Field TS, Ulcickas YM, Rolnick SJ, Quessenberry CP, Fouayzi H, Gurwitz JH, Wei F: Patterns and predictors of mammography utilization among breast cancer survivors. Cancer 106(11): 2482-8, Jun 2006 Notes: This publication was carried by over 270 print, TV and electronic media outlets on the first date of its release, included several media interviews (radio, print and TV), and was the number 1 trending health news items on Google news.

Corley DA, Jensen CD, Marks AR, Zhao WK, de Boer J, Levin TR, Doubeni C, Fireman BH, Quesenberry CP: Variation of Adenoma Prevalence by Age, Sex, Race, and Colon Location in a Large Population: Implications for Screening and Quality Programs. Clin Gastroenterol Hepatol 11(2): 172-80, Feb 2013 Notes: doi: 10.1016/j.cgh.2012.09.010. Epub 2012 Sep 14.

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Last updated: 01/13/2018
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