Megan S Lim

faculty photo
Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
Director, Division of Hematopathology Joint, Hospital of the University of Pennsylvania and Children’s Hospital of Philadelphia Department of Path and Lab Medicine, University of Pennsylvania
Director, Lymphoma Biology Program, Abramson Cancer Center, University of Pennsylvania (Philadelphia, Pa)
Hematopathologist, Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, (Philadelphia, PA)
Director, Hematopathology Fellowship Training Program, Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania
Director, Interim, Clinical Flow Cytometry Laboratory, Hospital of the University of Pennsylvania (Philadelphia, PA)
Hematopathologist, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania (Philadelphia, PA)
Department: Pathology and Laboratory Medicine

Contact information
Department of Pathology and Laboratory Medicine
Stellar Chance Office Suite 609C
422 Curie Blvd.
Philadelphia, PA 19104
Office: 215-898-4719
Fax: 215-898-9969
BS (Cell and Microbiology)
University of Calgary, 1983.
MS (Biochemistry, Cell Regulation Group, Department of Medical Biochemistry, Faculty of Medicine)
University of Calgary, 1985.
MD (Medicine)
University of Calgary, 1988.
PhD (Molecular Oncology)
University of Calgary joint with National Cancer Institute, National Institute of Health, 1999.
Permanent link

Description of Itmat Expertise

hematologic cancer
molecular pathogenesis
genomic analysis
mass spectrometry driven proteomics

Selected Publications

Önder Ö, Rolland DCM, Yuan Z-F, Garcia BA, Lim MS and Elenitoba-Johnson KSJ: Poster presentation "Characterization of Histone Post-Translational Modifications of Cutaneous T-cell Lymphomas" 65thAmerican Society for Mass Spectrometry Conference on Mass Spectrometry & Allied Topics June 2017.

Rolland DCM, Basrur V, Jeon YK, McNeil-Schwalm C, Fermin D, Conlon KP, Zhou Y, Ng SY, Tsou C-C, Brown NA, Thomas DG,. Bailey NG, Omenn GS, Nesvizhskii AI, Weinstock DM, Faryabi RB, Lim MS, and Elenitoba-Johnson KSJ: Functional Proteogenomics Reveals Biomarkers and Therapeutic Targets in Lymphoid Cancer. Proc Natl Acad Sci USA 114(25): 6581-86, June 2017 Notes: Epub: 2017 June 12.

Allen CE, Leatsch T, Mody R, Irwin MS, Lim MS, Adamson P, Seibel N, Parsons DW, Cho YJ and Janeway K on behalf of the Pediatric MATCH Target and Agent Prioritization Committee **: Target and Agent Prioritization for Children’s Oncology Group-National Cancer Institute Pediatric MATCH Trial. Journal of the National Cancer Institute. Oxford University Press, May 2017.

Lee S, Day NS, Miles RR, Perkins SL, Lim MS, Avello J, van de Ven C, Harrison L, El-Mallawany NK, Goldman S, Cairo MS: Comparative genomic expression signatures of signal transduction parhways and targets in paediatric Burkitt lymphoma: a Children's Oncology Group report. Br J Haemotol 177: 601-611, May 2017.

Wu R, Önder Ö, Rolland DCM, Elenitoba-Johnson KSJ, Lim MS: Poster presentation "Mass spectrometry-based proteomic profiling of Hodgkin lymphoma" The International Symposium on Childhood, Adolescent and Young Adult Hodgkin Lymphoma May 2017 Notes: Washington, DC.

Tasian SK, Hurtz C, Wertheim GB, Bailey NG, Lim MS, Harvey RC, I-Ming C, Willman CL, Astles R, Reshmi SC, Li MM, Frey NV, Luger SM, Carroll M, Perl AE: High incidence of Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia in Older Adults with B-ALL. Leukemia 31: 981-984, Apr 2017 Notes: Epub 2016 Dec 3.

Murga-Zamalloa CA, Mondoza-Reinoso V, Sahasrabuddhe AA, Rolland DCM, Hwang SR, McDonnell SR, Scialis AP, Wilcox RA, Bashur V, Elenitoba-Johnson KSJ, Lim MS. : NPM-ALK phosphorylates WASp Y102 and contributes to oncogenesis of anaplastic large cell lymphoma. Oncogene 36: 2085-2094, Apr 2017 Notes: Epub 2016 Oct 3.

Hwang SR, Murga-Zamalloa C, Brown N, Basappa J, McDonnell SR, Mendoza-Reinoso V, Basrur V, Wilcox R, Elenitoba-Johnson KSJ, Lim MS,: Pyrimidine tract-binding protein 1 mediates pyruvate kinase M2-dependent phosphorylation of signal transducer and activator of transcription 3 and oncogenesis in anaplastic large dell lymphoma. Lab Invest Apr 2017 Notes: Epub ahead of print.

Palacios G, Shaw T, Li Y, Singh RK, Valentine M, Sandlund JT, Lim MS, Mullighan CG, Leventaki V.: Novel ALK fusion in a case of Anaplastic Large Cell Lymphoma involving EEF1G, a subunit of the eukaryotic elongation factor-1 complex. Leukemia 3: 743-747, Mar 2017 Notes: Epub ahead of print 2016 Nov 14.

Fajgenbaum DC, Uldrick TS, Bagg A, Frank D, Wu D, Srkalovic G, Simpson D, Liu AY, Menke D, Shanmuganathan C, Lechowicz MJ, Wong RSM, Paessler M, Rossi JF, Ide M, Ruth J, Croglio M, Suarez A, Krymskaya V, Chadburn A, Colleoni G, Nasta S, Jayanthan R, Nabel C, Casper C, Dispenzieri A, Fossa A, Kelleher D, Kurzrock R, Voorhees P, Dogan A, Yoshizaki K, van Rhee F, Oksenhendler E, Jaffe ES, Elenitoba-Johnson KSJ, Lim MS: International, evidence-based consensus diagnostic criteria for HHV-8-negative/idiopathic Multicentric Castleman disease. Blood Jan 2017.

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Last updated: 11/21/2017
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