Jerilynn Radcliffe

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Professor of Clinical Psychology in Pediatrics at the Children's Hospital of Philadelphia
Director, Behavioral Neuroscience Core, The Children's Hospital of Philadelphia Clinical Translational Research Center
Consultant, The Children's Hospital of Philadelphia Institutional Review Board
Department: Pediatrics

Contact information
The Children's Hospital of Philadelphia
Division of Developmental and Behavioral Pediatrics
3400 Civic Center Blvd
CHOP North 1461
Philadelphia, PA 19104
Office: 215 590-7446
Fax: 215 590-3020
Bryn Mawr College, Cum Laude, 1970.

Diploma, Assumption Montessori Training Center, 1971.
MSEd (Psychological Services in Education)
University of Pennsylvania Graduate School of Education, 1975.
Ph.D. (Psychology)
University of Pennsylvania, 1981.
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Description of Research Expertise

I have participated in many research initiatives at CHOP in the areas of cognitive and psychosocial outcomes of treatment for chronic pediatric illnesses, originally pediatric brain tumor and sickle cell disease. I remain active in national multisite research efforts aimed at understanding the cognitive and behavioral effects of environmental metals upon children’s development. The Treatment of Lead-exposed Children’s Study, launched in 1993 as an NIH-sponsored multisite randomized controlled trial of the effects of succimer, an oral chelating agent, on mild to moderate levels of lead exposure in infants and toddlers, has studied the effects of lead, mercury and cadmium upon children’s behavior and development. These efforts continue.

I have also participated, and now direct, The MOM Program, a home visiting program for mothers living in poverty, designed to empower mothers to seek services to enhance their children’s development. The MOM Program grew out of the Philadelphia TLC Study, as program staff became more aware of the barriers faced by mothers living in poverty when they tried to seek services on behalf of their children. This study was initially led by Dr. Donald F. Schwarz, who is now the Deputy Mayor for Health and Opportunity for the City of Philadelphia. The MOM Program has become a flagship project within the City of Philadelphia for addressing the needs of mothers and children living in poverty within a greatly expanded City- and State-funded initiative. Results from The MOM Program have been presented nationally. The MOM Program is yet another interdisciplinary effort that exemplifies the contributions of pediatric psychology, in that I worked closely and collaboratively with colleagues in both pediatrics and nursing in the design, implementation, and evaluation of the program.

A final area of active research is in the area of HIV. I became involved in HIV clinical work early in the epidemic, when I was asked to conduct developmental evaluations on newly-diagnosed children. This gave rise to my overseeing the conduct of yearly cognitive evaluations of perinatally-exposed children. In 2005, I was asked to become part of a newly organized program, the Adolescent HIV Initiative, a clinic designed to provide clinical services to behaviorally infected adolescents with HIV. Here, I have designed the mental health program offered in the program and have conducted clinical research on service provision and clinical needs of the youth served. I participate in Adolescent Trials Network-funded studies of the neurocognitive effects of HAART and of the effectiveness of a cognitive-behavioral intervention to treat drug and alcohol abuse. In addition, I am engaged in research among African American adolescents and young men who have sex with men and who live with HIV, examining the effects of trauma, stigma, and spirituality on sexual health risk, towards developing more effective secondary prevention interventions with HIV-positive youth. .

Description of Itmat Expertise

Dr. Radcliffe studies sexual health risks for adolescents and young adults with HIV, as well as neurocognitive functioning and marijuana and alcohol use intervention. She also studies the effects of a home visiting program on the cognition and behaviors of children living in poverty.

Selected Publications

Liu H, Jawad A, Laney N, Hooper, S, Radcliffe, J, Moodalbail, D, Davatzikos, C, Schultz, R, Furth, S, & Detre, J. : Alterations in Cardiac-Correlated Brain BOLD Signal in Children with Chronic Kidney Disease. E-Poster presented at: International Society for Magnetic Resonance in Medicine Conference; Milan, Italy. May 2014.

Wagenman, K.L., Blake, T.P., Sanchez, S.M., Schultheis, M.T., Radcliffe, J., Berg, R.A., Dlugos, D.J., Topjian, A.A., & Abend, N.S.: Electrographic status epilepticus and long-term outcome in critically ill children. Neurology, 82; 396-404. Neurology 82, 2014.

Moodalbail D, Laney N, Gur R, Hooper, S.R., Radcliffe, J., Ruparel, K., Mott, A., Jawad, A.F., Furth, S.L.: Cognitive performance on a computerized neurocognitive battery in children and young adults with CKD. Poster presented at: American Society of Nephrology Kidney Week Conference; Atlanta, Georgia. Abstract publication: J Am Soc Nephrol 24(1), November 2013.

Cielo, C., Taylor, J.A., Vossough, A., Bradford, R., Radcliffe, J., Sullivan, A., & Marcus, C.L. : Obstructive sleep apnea in infants with cleft palate and tongue-based airway obstruction. American Academy of Sleep Medicine. Baltimore, MD. June 2013.

Xanthopoulos, M.S., Bradford, R., Berkowitz, R.I., Radcliffe, J., Tapia, I., Marcus, C.L. : Behavioral and neurocognitive functioning in obese and non-obese adolescents with and without obstructive sleep apnea syndrome. American Academy of Sleep Medicine. Baltimore, MD. June 2013.

Konstantinopoulou, S., Tapia, I.E., Sullivan, A., Cielo, C., Radcliffe, J., Pipan, M., Hanna, B., Gallagher, P.R., Carroll, M.E., & Marcus, C.L.: Association between polysomnographic parameters and neurocognitive and behavioral outcomes with children with Down syndrome. SLEEP 2013, Annual Meeting of the Associated Sleep Societies. Baltimore, MD. May 2013.

Moodabail, D., Radcliffe, J., Jawad, A.F., Reiser, K., Furth, S.L., & Hooper, S.R. : Neuropsychological profile of children and young adults with moderate to severe kidney disease. 15th International Conference on Dialysis, Advances in Chronic Kidney Disease. San Juan, Puerto Rico. January 2013.

Wang, Y., Dietrich, K.N., Radcliffe, J., Caldwell, K.L., & Rogan, W.J. : Postnatal exposure to methyl mercury and neuropsychological development in 7-year-old children in the United States. Child Neuropsychology 2013.

Moodalbail, D., Reiser, K.A., Detre, J.A., Schultz, R.T., Herrington, J.D., Davatzikos, C., Doshi, J.J., Erus, G., Liu, H-S., Radcliffe, J., Furth, S.L., & Hooper, S.R. : Sytematic review of structural and functional neuroimaging findings in children and adults with CKD. Clinical Journal of the American Society of Nephrology 8(8), 2013.

Radcliffe, J., Carlson, E.C., Mautone, J.A., Askew, M., Esposito, T.L., Zhao, H., O’Sullivan, A.L.: Predicting maternal engagement in a home visiting program. Annual Meeting, American Psychological Association August 2012

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Last updated: 03/12/2014
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