Jerilynn Radcliffe

faculty photo
Professor CE of Pediatrics
Director, Behavioral Neuroscience Core, The Children's Hospital of Philadelphia Clinical Translational Research Center
Consultant, The Children's Hospital of Philadelphia Institutional Review Board
Department: Pediatrics

Contact information
The Children's Hospital of Philadelphia
Division of Developmental and Behavioral Pediatrics
3400 Civic Center Blvd
CHOP North 1461
Philadelphia, PA 19104
Office: 215 590-7446
Fax: 215 590-3020
Bryn Mawr College, Cum Laude, 1970.

Diploma, Assumption Montessori Training Center, 1971.
MSEd (Psychological Services in Education)
University of Pennsylvania Graduate School of Education, 1975.
Ph.D. (Psychology)
University of Pennsylvania, 1981.
Permanent link

Description of Research Expertise

I have participated in many research initiatives at CHOP in the areas of cognitive and psychosocial outcomes of treatment for chronic pediatric illnesses, originally pediatric brain tumor and sickle cell disease. I remain active in national multisite research efforts aimed at understanding the cognitive and behavioral effects of environmental metals upon children’s development. The Treatment of Lead-exposed Children’s Study, launched in 1993 as an NIH-sponsored multisite randomized controlled trial of the effects of succimer, an oral chelating agent, on mild to moderate levels of lead exposure in infants and toddlers, has studied the effects of lead, mercury and cadmium upon children’s behavior and development. These efforts continue.

I have also participated, and now direct, The MOM Program, a home visiting program for mothers living in poverty, designed to empower mothers to seek services to enhance their children’s development. The MOM Program grew out of the Philadelphia TLC Study, as program staff became more aware of the barriers faced by mothers living in poverty when they tried to seek services on behalf of their children. This study was initially led by Dr. Donald F. Schwarz, who is now the Deputy Mayor for Health and Opportunity for the City of Philadelphia. The MOM Program has become a flagship project within the City of Philadelphia for addressing the needs of mothers and children living in poverty within a greatly expanded City- and State-funded initiative. Results from The MOM Program have been presented nationally. The MOM Program is yet another interdisciplinary effort that exemplifies the contributions of pediatric psychology, in that I worked closely and collaboratively with colleagues in both pediatrics and nursing in the design, implementation, and evaluation of the program.

A final area of active research is in the area of HIV. I became involved in HIV clinical work early in the epidemic, when I was asked to conduct developmental evaluations on newly-diagnosed children. This gave rise to my overseeing the conduct of yearly cognitive evaluations of perinatally-exposed children. In 2005, I was asked to become part of a newly organized program, the Adolescent HIV Initiative, a clinic designed to provide clinical services to behaviorally infected adolescents with HIV. Here, I have designed the mental health program offered in the program and have conducted clinical research on service provision and clinical needs of the youth served. I participate in Adolescent Trials Network-funded studies of the neurocognitive effects of HAART and of the effectiveness of a cognitive-behavioral intervention to treat drug and alcohol abuse. In addition, I am engaged in research among African American adolescents and young men who have sex with men and who live with HIV, examining the effects of trauma, stigma, and spirituality on sexual health risk, towards developing more effective secondary prevention interventions with HIV-positive youth. .

Description of Itmat Expertise

Dr. Radcliffe studies sexual health risks for adolescents and young adults with HIV, as well as neurocognitive functioning and marijuana and alcohol use intervention. She also studies the effects of a home visiting program on the cognition and behaviors of children living in poverty.

Selected Publications

Hartung EA, Erus G, Jawad AF, Laney N, Doshi JJ, Hooper S, Radcliffe J, Davatzikos C, & Furth SL: Brain Magnetic Resonance Imaging Findings in Children and Young Adults with CKD. Am J Kidney Disease November 2017.

Thomas, NH, Xanthopoulos, MS, Kim, JY, Giordani, B, Hodges, E, Chervin, RD, Paruthi, S, Rosen, CL, Arens, R, Radcliffe, J. & Marcus, CL.: Effects of adenotonsillectomy on parent-reported behavior in children with obstructive sleep apnea. Sleep 40(4), 2017.

Ruebner, RL, Laney N., Young, K., Hartung, EA, Hooper, SR, Radcliffe, J, Furth, SL. : Neurocognitive dysfunction in children and young adults with chronic kidney disease. Am J Kidney Dis 67(4): 567-75, April 2016.

Hartung EA, Kim JY, Laney N, Hooper SR, Radcliffe J, Port AM, Gur RC, Furth SL: Evaluation of neurocognition in youth with CKD using a novel computerized neurocognitive battery. Clin J Am Soc Nephrol 11(1): 39046, Jan 2016.

Zanthopoulos, MS, Gallagher PR, Berkowitz RI, Radcliffe J, Bradford R, Marcus, CL: Neurobehavioral functioning in adolescents with and without obesity and obstructive sleep apnea. Sleep 39(1), Jan 2016.

Konstantinopoulou S, Tapia IE, Kim JY, Xanthopoulos MS, Radcliffe J, Cohen MS, Hanna BD, Pipan M, Cielo C, Zemel B, Amin R, Bradford R, Traylor J, Shults J, Marcus CL: Relationship between obstructive sleep apnea cardiac complications and sleepiness in children with Down syndrome. Sleep Medicine 17: 18-24, 2016.

Nichols, S.L., Bethel, J., Kapogiannis, B.G., Li, T., Woods, S.P., Patton, E.D., Ren, W., Thornton, S.E., Major-Wilson, H.O., Puga, A.M., Sleasman, J.W., Rudy, B.J., Wilson, C.M., Garvie, P.A.: Antretroviral treatment initiation does not differentially alter neurocognitive functioning over time in youth with behaviorally acquired HIV. J Neurovirology 22(2): 218-30, 2016.

Meert, K.L., Telfored, R., Holubkov, R., Slomine, B.S., Christensen, J.R., Dean, J.M., Moler, F.W.: Therapeutic Hypothermia after Pediatric Cardiac Arrest (THAPCA) Trial Investigators: Pediatric out-of-hospital cardiac arrest characteristics and their association with survival and neurobehavioral outcome. Pediatric Critical Care Medicine 17(12): e543-e550, 2016.

Sun, LS, Guohua, L, Miller, TLK, Salorio, C., Byrne, MW, Bellinger, DC, Ing, CH, Park, R, Radcliffe, J., Hays, SR, DiMaggio, CJ, Cooper, TJ, Rauh, V, Maxwell, LG, Youn, A, &7 McGowan, FX.: Association between a single general anesthetic exposure before age 36 months and neurocognitive outcomes in later childhood. J American Medical Association 315(21): 1-10, 2016.

Cielo, CM, Taylor JA, Vossough A, Radcliffe J, Thomas A, Bradford R, Lioy J, Tapia IE, Assadsangabi R, Shults J, Marcus CL.: Evolution of obstructive sleep apnea in infants with cleft palate and micrognathi. J Clinical Sleep Medicine 12(7): 979-987, 2016.

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Last updated: 04/30/2018
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