Jason N. Rosenbaum

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Assistant Professor of Clinical Pathology and Laboratory Medicine
Associate Director, Molecular Genetic Pathology Fellowship, University of Pennsylvania, Perelman School of Medicine Department of Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine

Contact information
3020 Market Street, Suite 220
Philadelphia, PA 19128
Office: 267-586-2525
Fax: 215-898-9817
Lab: 215-349-8456
Education:
BA (Molecular and Cell Biology/Integrative Biology)
University of California at Berkley, 1998.
MD (Medicine)
Northwestern University Feinberg School of Medicine, 2011.
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Description of Itmat Expertise

Diagnostic and prognostic test design

Selected Publications

J.N. Rosenbaum, R. Bloom, J.T. Forys, J. Hiken, J.R. Armstrong, J. Branson, S. McNulty, P.D. Velu, K. Pepin, H. Abel, C.E. Cotrell, J.D. Pfeifer, S. Kulkarni, R. Govindan, E.Q. Konnick, C.M. Lockwood, E.J. Duncavage: Genomic Heterogeneity of ALK Fusion Breakpoints in Non-Small Cell Lung Cancer. Modern Pathology. Nature, 2018.

P.S. Rush, J.N. Rosenbaum, R.M. Baus, D.D. Bennett, R.V. Lloyd. (2017): INSM1: A Novel Nuclear Marker in Merkel Cell Carcinoma (Cutaneous Neuroendocrine Carcinoma). Journal of Cutaneous Pathology November 2017.

R.T. Sussman, A. Viaene, P. Velu, S. Schaffer, J. Rosenbaum, J. Morrissette, M. Nasrallah: Evaluation of Intraoperative Sampling for Genomic Analysis of Central Nervous System (CNS) Tumors by Next-Generation Sequencing (NGS). Journal of Molecular Diagnostics 16(699), November 2017.

Orr, C, Morrissette, JD, Rosenbaum, JN. : “Unburdening” Variant Review for High Tumor Mutation Burden (TMB) Cases in a Clinical Next-Generation Sequencing (NGS) Assay. Journal of Molecular Diagnostics 16(699), November 2017.

P.R. Hess, P.D. Velu, A. Bigdeli, J.J. Morrissette, J.N. Rosenbaum, J. Roth: Discordance Among Biomarkers for Anti-PD1 Therapy Response: Tumor Mutational Burden and Anti-PD-L1 Staining. Journal of Molecular Diagnostics 16(699), November 2017.

P. Velu, A. Bigdeli, P.R. Hess, J.J. Roth, J.N. Rosenbaum, J.J. Morrissette: Calculation of Mutational Burden in a Clinical Targeted Next-Generation Sequencing (NGS) Panel for Solid Tumors. Journal of Molecular Diagnostics 16(699), November 2017.

A. Bigdeli, R. Sussman, A. Schrank-Hacker, V. Aikawa, J. Rosenbaum, J.D. Morrissette, R.B. Faryabi : Evaluation of Copy Number Variation Detection Methods for Amplicon Sequencing Assays Journal of Molecular Diagnostics 16(699), November 2017.

C. Paolillo, A. Oran, J.N. Rosenbaum, J.J. Morrissette, R. Sussman. : Detection of MET Exon 14 Skipping in Non-Small Cell Lung Cancer (NSCLC) via RNA Anchored Multiplexed PCR and DNA Next-Generation Sequencing. Journal of Molecular Diagnostics 16(699), November 2017.

A. Oran, J. Grubb, D.B. Lieberman, R.T. Sussman, J.J. Morrissette, J.N. Rosenbaum.: Comparison of ALK, RET, and ROS1 Gene Fusion Detection by Next-Generation Sequencing, Fluorescence in situ Hybridization, and Immunohistochemistry in Non-Small Cell Lung Cancer. Journal of Molecular Diagnostics 16(699), November 2017.

J.N. Rosenbaum, P. Weisman: The Evolving Role of Companion Diagnostics for Breast Cancer in an Era of Next-Generation Omics. The American Journal of Pathology 187(10): 2185, October 2017.

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Last updated: 11/29/2017
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