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Welcome to the Center For Advanced Metabolic Imaging in Precision Medicine (CAMIPM), a National Center for Biomedical Imaging and Bioengineering (NCBIB) in the Perelman School of Medicine at the University of Pennsylvania.

Principal Investigator: Ravinder Reddy, Ph.D., Director and Professor of Radiology

The CAMIPM develops and translates cutting edge noninvasive metabolic imaging biomarkers for use in biomedical research.  Technology development is focused in four major application areas:  Oncology, Cardiovascular disease, Neuropsychiatry, and Musculoskeletal disorders.  These technologies will have substantial impact on the fundamental understanding of disease mechanisms, early diagnosis, and development of novel therapies for several diseases such as Alzheimer’s disease, Epilepsy, Arthritis, Cancer, Stroke, and heart disease, and thus contribute to precision medicine and enhanced patient care.  The facility’s core sections provide research and computing resources for numerous user, collaborative, and training projects.

The focus of this center is on developing instrumentation, methodologies, and data analysis techniques for the quantitative assessment of functional, structural, and metabolic parameters in humans with the use of chemical exchange weighted molecular magnetic resonance imaging (MRI), MRI of oxygen consumption, down field spectroscopy, and diffuse optical imaging techniques.

We are supported by the NIBIB under Grant No. P41 EB029460.

CAMIPM Seminar Series

"Magnetic Resonance Imaging and Obstructive Sleep Apnea in Adults"

Rajesh Kumar, Ph.D.

Rajesh Kumar, PhD (remote)

Professor In-Residence

Departments of Anesthesiology, Radiological Sciences, and Bioengineering

University of California at Los Angeles

URL: https://bri.ucla.edu/people/rajesh-kumar/

Abstract:

Novel magnetic resonance imaging and spectroscopy procedures and analytical methods offer a unique opportunity to examine the brain structural, metabolic, hemodynamic, blood brain barrier, resting-state functional connectivity, and functional responses to autonomic challenges status in obstructive sleep apnea adults. In a series of experiments in patients with obstructive sleep apnea, the characterization of brain injury, abnormal metabolites, hemodynamics, resting-state functional connectivity, and abnormal functional responses to autonomic challenges, in autonomic, mood, and cognition mediating sites, functions that are deficient in the obstructive sleep apnea condition will be presented. Also, potential pathological mechanisms, including compromised cerebral blood flow and blood brain barrier function, contributing to brain tissue changes and functions in obstructive sleep apnea will be discussed. In addition, various magnetic resonance imaging based analytical procedures will also be described that can be used to other conditions affecting the brain.

Date:  Thursday, October 16, 2025

Location: Room B1 Basement Stellar Chance Labs

Time: 3:00 PM

Zoom link: 

https://pennmedicine.zoom.us/j/93435730386?pwd=YmxHa2I5Ny9wWWlZNzBPU3ZJR05sQT09

Meeting ID: 934 3573 0386

Passcode: 897997

 

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