Personnel
Principal Investigator
Garret A. FitzGerald, MD, FRS
Dr. FitzGerald's research has been characterized by an integrative approach to elucidating the mechanisms of drug action, drawing on work in cells, model organisms and humans. His work contributed substantially to the development of low-dose aspirin for cardioprotection. FitzGerald's lab was the first to predict and then mechanistically explain the cardiovascular hazard from NSAIDs. He has also discovered many products of lipid peroxidation and established their utility as indices of oxidant stress in vivo. His laboratory was the first to discover a molecular clock in the cardiovascular system and has studied the importance of peripheral clocks in the regulation of cardiovascular and metabolic function.
Faculty
Emanuela Ricciotti, PharmD, PhD
Research Assistant Professor
emanuela@pennmedicine.upenn.edu
215-898-9391
Research Expertise: Genomic, proteomic and metabolomics analysis of inflammatory pathways in vascular cells.
Staff
Robin Joshi
Research Investigator, Senior
Robin.Joshi@Pennmedicine.upenn.edu
Research Interests: Single cell proteomics, metabolomics, lipidomics in circadian rhythms using mass spectrometery
Sean Kelch
Research Specialist
Sean.Kelch@Pennmedicine.upenn.edu
Research Interests: circadian rhythms, metabolism, and biological imaging
Ryan McConnell
Research Specialist A
ryan.mcconnell@pennmedicine.upenn.edu
Research Interests: The interplay between immune-checkpoint inhibition and eicosanoid modulation on the immune
response in atherosclerosis
Georgios K. Paschos, PhD
Research Investigator, Senior
gpaschos@pennmedicine.upenn.edu
215-898-8360
Research Expertise: Circadian regulation of metabolism
Carsten C. Skarke, MD
Research Investigator, Senior
cskarke@pennmedicine.upenn.edu
215-662-7186
Research Expertise: Human Clock Biology and Human Phenomics
Sarah Teegarden
Associate Director / Lab Manager
sarahtee@pennmedicine.upenn.edu
Research Interests: Circadian rhythms, fitness, and metabolism
Takae Tanosaki
Research Specialist
Takae.Tanosaki@Pennmedicine.upenn.edu
Research Interests: Respiratory Medicine, Allergy, COX2 and lipid metabolism
Soon Yew Tang
Research Investigator, Senior
tangsoon@pennmedicine.upenn.edu
Research Interests: The role of prostaglandins in cardiometabolic function
Postdocs
Kayla Barekat
Postdoc Researcher
kbarekat@pennmedicine.upenn.edu
Research Interests: NSAID-microbiome interactions and gastroenteropathy
Ujjalkumar Das
Postdoc Researcher
Ujjalkumar.Das@Pennmedicine.upenn.edu
Research Interests: Biological role of low abundance lipids and proteomic perturbations in chronobiology using Mass Spectrometry
Soumita Ghosh
Senior Research Investigator
soumita@pennmedicine.upenn.edu
Research Interests: Interindividual variability of NSAID pharmacokinetics and pharmacodynamics
Liz Hennessy
Research Associate
ehenn@pennmedicine.upenn.edu
Research Interests: Long non-coding RNAs as regulators of cardiovascular disease and inflammation
Nadim El Jamal
Postdoc Researcher
nadim.eljamal@pennmedicine.upenn.edu
Research interests: Circadian rhythms, cardiovascular disease, aging
Ronan Lordan
Postdoc Researcher
ronan.lordan@pennmedicine.upenn.edu
Research Interests: Circadian dysfunction, aging, and metabolism