FMIG Functional and Metabolic Imaging Group
Ventilation and Oxygen Tension Imaging
Specific Ventilation Imaging
Multi-breath vs Single-breath Maneuver
Human Passive Gas Delivery Device
Real-Time Metabolic Profiling
Lung CSI of HP 13C-Pyruvate
The goal of the Functional and Metabolic Imaging Group (FMIG) is the development and application of novel hyperpolarized MRI techniques capable of diagnosing a variety of pulmonary and metabolic disorders. Specifically, our research activities at FMIG is divided into four general branches:
- The development of novel imaging techniques for the quantitative assessment of pulmonary structure and function through use of hyperpolarized gas (3He and 129Xe).
- Development of real-time metabolic imaging techniques to investigate the use of hyperpolarized 13C-labeled metabolites (e.g. [1-13C]pyruvate) for imaging lung perfusion and pulmonary pH, as well as detecting aberrant metabolism, which is a key pathological indication for a number of disease states, including cancer in other organs including liver, brain and heart.
- Study of the Dynamic Nuclear polarization (DNP) and Optical pumping technologies and polarization dominant relaxation mechanisms with the aim of increasing polarization levels as well extension of longitudinal relaxation.
- Implementation of rapid imaging pulse sequences and their applications in hyperpolarized MRI.