From Phenotype to Genotype and Everything In-Between: New Computational Tools for Disease Gene Discovery

The Center for Genetics and Complex Traits (CGACT) of the Perelman School of Medicine at the University of Pennsylvania will hold a Symposium on Advances in Genomics, Epidemiology and Statistics (SAGES) on June 3, 2016 in the Arthur H. Rubenstein Auditorium of the Smilow Center for Translational Research in Philadelphia, PA.


Advances in technology and significant decrease in the associated costs are driving progress in genomic studies. Studies of whole exome and genome sequences of complex traits in large samples are becoming increasingly common. Other sources of high-dimensional information, including expression, epigenetic, metabolic and microbiomic data, are also being collected in disease and control samples. To fully understand the complex bases of human disease and trait variation, all of these factors should be properly considered in a unified analytical framework, together with epidemiological data on environmental exposures and other risk factors. SAGES brings together an interdisciplinary group of scientists working in the fields of genomics, epidemiology, and statistics, to address these challenges. The forum provides an opportunity for scientists at all levels in their career to convene and review new developments in these areas of research. The symposium aims to facilitate exchange of ideas and promote interactions and collaborations among participants.

Organizing Committee:

  • Marcella Devoto, Chair, University of Pennsylvania, The Children's Hospital of Philadelphia
  • Joan Bailey-Wilson, National Human Genome Research Institute
  • Iuliana Ionita-Laza, Columbia University
  • Peter Kanetsky, Moffitt Cancer Center
  • Hongzhe Li, University of Pennsylvania
  • Nandita Mitra, University of Pennsylvania
  • Adam Naj, University of Pennsylvania
  • Timothy Rebbeck, Harvard University
  • Ingo Ruczinski, Johns Hopkins University

Funding for this conference was made possible in part by grant R13 HG007809 from the National Human Genome Research Institute, National Institute of Environmental Health Sciences and National Institute on Deafness and Other Communication Disorders. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

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For more information, please contact Jennifer Forbes-Nicotera at or 215.573.9729

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