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Bede

Bede Portz is a postdoctoral researcher. He received his Ph.D. in biochemistry from Pennsylvania State University where he studied the RNA Polymerase II CTD using a combination of biophysical, biochemical and genetic approaches. Bede received his B.S. from Pennsylvania State University in microbiology.

Publications

Eric B. Gibbs, Tatiana N. Laremore, Grace A. Usher, Bede Portz, Erik C. Cook, and Scott A. Showalter. Substrate Specificity of the Kinase P-TEFb towards the RNA Polymerase II C-Terminal Domain. Biophysical Journal. doi: 10.1016/j.bpj.2017.09.011 (2017). pdf file link

Bede Portz, Feiyue Lu, Eric B. Gibbs, Joshua E. Mayfield, M. Rachel Mehaffey, Yan Jessie Zhang, Jennifer S. Brodbelt, Scott A. Showalter, and David S. Gilmour. Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain. Nature Communications. 8, 15231 (2017). pdf file link

Eric B. Gibbs, Feiyue Lu, Bede Portz, Michael J. Fisher, Brenda P. Medelline, Tatiana N. Laremore, Yan Jessie Zhang, David S. Gilmour, and Scott A. Showalter. Phosphorylation induces sequence-specific conformational switches in the RNA polymerase II C-terminal domain. Nature Communications. 8, 15233 (2017). pdf file link


 

 

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Department of Biochemistry & Biophysics
p3
University of Pennsylvania