2009
34. Roberts B.E., M.L. Duennwald, H. Wang, C. Chung, N.P. Lopreiato, E.A. Sweeny, M.N. Knight and J. Shorter^. (2009). A synergistic small-molecule combination directly eradicates diverse prion strain structures. Nat. Chem. Biol. 5(12):936-946. pdf file link (^Co-Corresponding author).
33. Watt, B., G. van Niel, D.M. Fowler, I. Hurbain, K.C. Luk, S.E. Stayrook, M.A. Lemmon, G. Raposo, J. Shorter, J.W. Kelly and M.S. Marks. (2009). N-terminal domains elicit formation of functional Pmel17 amyloid fibrils. J. Biol. Chem. 284: 35543-35555. pdf file link
32. Johnson, B.S., D. Snead, J.J. Lee, J. M. McCaffery, J. Shorter^ and A.D. Gitler. (2009). TDP-43 is intrinsically aggregation-prone and Amyotrophic Lateral Sclerosis-linked mutations accelerate aggregation and increase toxicity. J. Biol. Chem. 284(30):20329-39. pdf file link (^Co-Corresponding author).
31. Wendler, P., J. Shorter, D. Snead, C. Plisson, D.K. Clare, S. Lindquist and H.R. Saibil. (2009). Motor mechanism for protein threading through Hsp104. Mol Cell. 34:81-92. pdf file link
2008
30. Sweeny, E.A. and J. Shorter^. (2008). Prion proteostasis: Hsp104 meets its supporting cast. Prion. 2(4): 135-40. pdf file link (^Corresponding author)
29. Skinner, J.J., S. Wood, J. Shorter, S.W. Englander, and B.E. Black. (2008). The Mad2 partial unfolding model: regulating mitosis through Mad2 conformational switching. J. Cell Biol. 183: 761-768. pdf file link
28. Shorter, J.^ and S. Lindquist. (2008). Hsp104, Hsp70 and Hsp40 interplay regulates formation, growth and elimination of Sup35 prions. EMBO J. 27 (20): 2712–2724. pdf file link (^Corresponding author).
27. Lo Bianco, C.*, J. Shorter*^, E. Régulier, H. Lashuel, T. Iwatsubo, S. Lindquist and P. Aebischer. (2008). Hsp104 antagonizes alpha-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson’s disease. J. Clin. Invest. 118:3087-3097. pdf file link (*Authors contributed equally to this work. ^Co-Corresponding author)
26. Maday, S., E. Anderson, H.C. Chang, J. Shorter, A. Satoh, J. Sfakianos, H. Foelsch, J.M. Anderson, Z. Walther, and I. Mellman. (2008). A PDZ-binding motif controls basolateral targeting of syndecan-1 along the biosynthetic pathway in polarized epithelial cells. Traffic. 9: 1915–1924. pdf file link
25. Roberts, B.E. and J. Shorter^. (2008). Escaping Amyloid Fate. Nat. Struct. Mol. Biol. 15(6):544-546. pdf file link (^Corresponding author)
24. Wang, H., M.L. Duennwald, B.E. Roberts, L.M. Rozeboom, Y.L. Zhang, A.D. Steele, R. Krishnan, L.J. Su, D. Griffin, S. Mukhopadhyay, E.J. Hennessy, P. Weigele, B.J. Blanchard, J. King, A.A. Deniz, S.L. Buchwald, V.M. Ingram, S. Lindquist, and J. Shorter^. (2008). Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs. Proc Natl Acad Sci USA 105(20):7159-7164. pdf file link (^Co-Corresponding author)
23. Sadlish H., H. Rampelt, J. Shorter, R.D. Wegrzyn, C. Andréasson, S. Lindquist, and B. Bukau. (2008). Hsp110 chaperones regulate prion formation and propagation in S. cerevisiae by two discrete activities. PLoS ONE 3(3):e1763. pdf file link
22. Shorter, J.^ (2008). Hsp104: a weapon to combat diverse neurodegenerative disorders. Neurosignals 16:63-74. pdf file link (^Corresponding author)
21. Gitler, A.D., B.J. Bevis, J. Shorter , K.E. Strathearn, S. Hamamichi, L.J. Su, K.A. Caldwell, G.A. Caldwell, J.C. Rochet, J.M. McCaffery, C. Barlowe, and S. Lindquist. (2008). The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis. Proc Natl Acad Sci USA 105(1):145-150. pdf file link
2007
20. Wendler, P., J. Shorter, C. Plisson, A.G. Cashikar, S. Lindquist, and H.R. Saibil. (2007). Atypical AAA+ subunit packing creates an expanded cavity for disaggregation by the protein-remodeling factor Hsp104. Cell 131:1366-1377. pdf file link
19. Gitler, A. D., and J. Shorter^ (2007). Prime time for alpha-synuclein. J. Neurosci. 27:2433-2434. pdf file link (^Co-Corresponding author)
18. Doyle, S. M.*, J. Shorter*, M. Zolkiewski, J.R. Hoskins, S. Lindquist, and S. Wickner. (2007). Asymmetric deceleration of ClpB or Hsp104 ATPase activity unleashes protein-remodeling activity. Nat. Struct. Mol. Biol. 14:114-122. pdf file link (*Authors contributed equally to this work)
2006
17. Shorter, J., and S. Lindquist. (2006). Destruction or potentiation of different prions catalyzed by similar Hsp104 remodeling activities. Mol. Cell 23:425-438. pdf file link
2005
16. Shorter, J.^, and S. Lindquist. (2005). Prions as adaptive conduits of memory and inheritance. Nat. Rev. Genetics 6:435-450. pdf file link (^Co-Corresponding author)
15. Beard, M.B., A. Satoh, J. Shorter, and G. Warren. (2005). A cryptic Rab1-binding site in the p115 tethering protein. J. Biol Chem. 280(27):25840-25848. pdf file link
14. Shorter, J., and S. Lindquist. (2005). Navigating the ClpB channel to solution. Nat. Struct. Mol. Biol. 12:4-6. pdf file link
2004
13. Shorter, J., and S. Lindquist. (2004). Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers. Science 304:1793-1797. pdf file link
2003
12. Wang, Y., J. Seemann, M. Pypaert, J. Shorter, and G. Warren. (2003). A direct role for GRASP65 as a mitotically regulated Golgi stacking factor. EMBO J. 22(13):3279-90. pdf file link
2002
11. Shorter, J.^, and G. Warren. (2002). Golgi Architecture and Inheritance. Annu. Rev. Cell Dev. Biol. 18:379-420. pdf file link (^Co-Corresponding author)
10. Müller, J.M.*, J. Shorter*, R. Newman, K. Deinhardt, Y. Sagiv, Z. Elazar, G. Warren, and D.T. Shima. (2002). Sequential SNARE disassembly and GATE-16/GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusion. J. Cell Biol. 157:1161-1173. pdf file link (*Authors contributed equally to this work)
9. Shorter, J., M.B. Beard, J. Seemann, A.B. Dirac-Svejstrup, and G. Warren. (2002). Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115. J. Cell Biol. 157:45-62. pdf file link
2000
8. Dirac-Svejstrup, A.B., J. Shorter, M.G. Waters, and G. Warren. (2000). Phosphorylation of the vesicle-tethering protein p115 by a casein kinase II-like enzyme is required for Golgi reassembly from isolated mitotic fragments. J. Cell Biol. 150:475-488. pdf file link
7. Meyer, H. H., J.G. Shorter, J. Seemann, D. Pappin, and G. Warren. (2000). A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways. EMBO J. 19:2181-2192. pdf file link
6. Shorter, J. (2000). Molecular mechanisms regulating Golgi architecture during the mammalian cell division cycle. Ph.D. Thesis (University College London).
5. Barr, F.A., and J. Shorter. (2000). Membrane traffic: do cones mark sites of fission? Curr. Biol. 10:R141-144. pdf file link
4. Lesa, G.M., J. Seemann, J. Shorter, J. Vandekerckhove, and G. Warren. (2000). The amino-terminal domain of the Golgi protein Giantin interacts directly with the vesicle-tethering protein p115. J. Biol. Chem. 275:2831-2836. pdf file link
1999
3. Müller, J.M., C. Rabouille, R. Newman, J. Shorter, P. Freemont, G. Schiavo, G. Warren, and D.T. Shima. (1999). An NSF function distinct from ATPase-dependent SNARE disassembly is essential for Golgi membrane fusion. Nat. Cell Biol. 1:335-340. pdf file link
2. Shorter, J., R. Watson, M.E. Giannakou, M. Clarke, G. Warren, and F.A. Barr. (1999). GRASP55, a second mammalian GRASP protein involved in the stacking of Golgi cisternae in a cell-free system. EMBO J. 18:4949-4960. pdf file link
1. Shorter, J.^, and G. Warren. (1999). A role for the vesicle tethering protein, p115, in the post-mitotic stacking of reassembling Golgi cisternae in a cell-free system. J. Cell Biol. 146:57-70. pdf file link (^Corresponding author)
