Functional Neurogenesis and Epigenetic/Epitranscriptomic Mechanisms in the Nervous System
Research in Dr. Hongjun Song's laboratory focuses on two core topics: (1) neural stem cell regulation and neurogenesis in the developing and adult mammalian brain and how these processes affect neural function; (2) epigenetic and epitranscriptomic mechanisms and their functions in the mammalian nervous system. The lab is also interested in addressing how dysfunction of these mechanisms may be involved in brain disorders.
As a newly established group at the University of Pennsylvania Perelman School of Medicine, we are looking forward to being a part of the community at Penn. At this time, we are seeking Postdoctoral Fellows and Graduate Students to join the lab. In addition, the lab is always looking for Undergraduate Students who are enthusiastic about stem cell, neurobiology and epigenetic research. Please contact us to inquire about opportunities within our lab.
Congratulations to Eunchai Kang and collaborators on their recent publication in Neuron
November 2, 2017
Eunchai Kang published her collaborative work with Mingjie Zhang's group in Hong Kong in NEURON on a multifaceted approach to investigate how risk factors for psychiatric disorders affect neural development using NMR spectroscopy, imaging, animal models, and patient iPSC-derived brain organoids.
Congratulations to Ki-Jun Yoon, Francisca Rojas Ringeling, Caroline Vissers and collaborators for their paper in Cell on the identification of an epitranscriptomic mechanisms regulating mouse and human cortical neurogenesis.
September 28, 2017
m6A-dependent mRNA decay is critical for proper transcriptional prepatterning in mammalian cortical neurogenesis.