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Mark Anthony Sellmyer, MD, PhD
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Assistant Professor of Radiology
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Department: Radiology
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Graduate Group Affiliations
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Contact information
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University of Pennsylvania
23 Perelman School of Medicine
21 Department of Radiology
4b 3400 Spruce St., 1 Silverstein, Ste. 130
Philadelphia, PA 19104
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23 Perelman School of Medicine
21 Department of Radiology
4b 3400 Spruce St., 1 Silverstein, Ste. 130
Philadelphia, PA 19104
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Office: 617-543-6546
3e Lab: 215-573-3212
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3e Lab: 215-573-3212
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Publications
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Links
a7 Search PubMed for articles
66 Sellmyer Lab Webpage
85 Codirector of the Center for Translational Chemical Biology
63 Sellmyer Lab Twitter Feed
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a7 Search PubMed for articles
66 Sellmyer Lab Webpage
85 Codirector of the Center for Translational Chemical Biology
63 Sellmyer Lab Twitter Feed
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Education:
21 7 BS 16 (Chemistry) c
3f Massachusetts Institute of Technology , 2004.
21 7 MD c
30 Stanford Medical School, 2012.
21 8 PhD 29 (Chemical and Systems Biology) c
30 Stanford Medical School, 2012.
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Permanent link21 7 BS 16 (Chemistry) c
3f Massachusetts Institute of Technology , 2004.
21 7 MD c
30 Stanford Medical School, 2012.
21 8 PhD 29 (Chemical and Systems Biology) c
30 Stanford Medical School, 2012.
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18 Chemical Biology
19 Synthetic Biology
11 Radiology
22 Nuclear Imaging and Therapy
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Description of Research Expertise
22 Molecular Imaging18 Chemical Biology
19 Synthetic Biology
11 Radiology
22 Nuclear Imaging and Therapy
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144 Etersque, J. M., Lee, I. K., Sharma, N., Xu, K., Ruff, A., Northrup, J. D., Sarkar, S., Nguyen, T., Lauman, R., Burslem, G. M., Sellmyer, M. A.: Regulation of eDHFR-tagged proteins with trimethoprim PROTACs. Nat Commun 14(1): 7071, Nov 2023.
161 Lee IK, Noguera-Ortega E, Xiao Z, Todd L, Scholler J, Song D, Liousia M, Lohith K, Xu K, Edwards KJ, Farwell MD, June CH, Albelda SM, Puré E, Sellmyer MA: Monitoring Therapeutic Response to Anti-FAP CAR T Cells Using [18F]AlF-FAPI-74. Clin Cancer Res 28(24): 5330-5342, Dec 2022.
110 Edwards KJ, Chang B, Babazada H, Lohith K, Park DH, Farwell MD, Sellmyer MA: Using CD69 PET Imaging to Monitor Immunotherapy-Induced Immune Activation. Cancer Immunol Res 10(9): 1084-1094, Sept 2022.
236 Iris K Lee, Daniel A Jacome, Joshua K Cho, Vincent Tu, Anthony J Young, Tiffany Dominguez, Justin D Northrup, Jean M Etersque, Hsiaoju S Lee, Andrew Ruff, Ouniol Aklilu, Kyle Bittinger, Laurel J Glaser, Daniel Dorgan, Denis Hadjiliadis, Rahul M Kohli, Robert H Mach, David A Mankoff, Robert K Doot, Mark A Sellmyer: Imaging sensitive and drug-resistant bacterial infection with [11C]-trimethoprim. The Journal of Clinical Investigation 132(18): e156679, Mar 2023 Notes: doi: 10.1172/JCI156679.
d2 Mankoff DA, Sellmyer MA: PET of Fibroblast-Activation Protein for Breast Cancer Diagnosis and Staging. Radiology 302(1): 48-49, Jan 2022.
103 Mark A Sellmyer, Iris K Lee, David A Mankoff: Building the bridge: molecular imaging biomarkers for 21st century cancer therapies. Journal of Nuclear Medicine 62(12): 1672–6, Dec 2021.
139 Jacome, D. A., Northrup, J. D., Ruff, A. J., Reilly, S. W., Lee, I. K., Blizard, G. S., Sellmyer, M. A.: A Chemical Approach for Programmable Protein Outputs Based on Engineered Cell Interactions. ACS Chem Biol 16(1): 52-57, Jan 2021.
182 Sellmyer Mark A, Richman Sarah A, Lohith Katheryn, Hou Catherine, Weng Chi-Chang, Mach Robert H, O'Connor Roddy S, Milone Michael C, Farwell Michael D: Imaging CAR T Cell Trafficking with eDHFR as a PET Reporter Gene. Molecular therapy : the journal of the American Society of Gene Therapy 28(1): 42-51, Jan 2020.
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Selected Publications
192 Lee, I. K., Sharma, N., Noguera-Ortega, E., Liousia, M., Baroja, M. L., Etersque, J. M., Pham, J., Sarkar, S., Carreno, B. M., Linette, G. P., Pure, E., Albelda, S. M., Sellmyer, M. A.: A genetically encoded protein tag for control and quantitative imaging of CAR T cell therapy. Mol Ther 31(12): 3564-3578, Nov 2023.144 Etersque, J. M., Lee, I. K., Sharma, N., Xu, K., Ruff, A., Northrup, J. D., Sarkar, S., Nguyen, T., Lauman, R., Burslem, G. M., Sellmyer, M. A.: Regulation of eDHFR-tagged proteins with trimethoprim PROTACs. Nat Commun 14(1): 7071, Nov 2023.
161 Lee IK, Noguera-Ortega E, Xiao Z, Todd L, Scholler J, Song D, Liousia M, Lohith K, Xu K, Edwards KJ, Farwell MD, June CH, Albelda SM, Puré E, Sellmyer MA: Monitoring Therapeutic Response to Anti-FAP CAR T Cells Using [18F]AlF-FAPI-74. Clin Cancer Res 28(24): 5330-5342, Dec 2022.
110 Edwards KJ, Chang B, Babazada H, Lohith K, Park DH, Farwell MD, Sellmyer MA: Using CD69 PET Imaging to Monitor Immunotherapy-Induced Immune Activation. Cancer Immunol Res 10(9): 1084-1094, Sept 2022.
236 Iris K Lee, Daniel A Jacome, Joshua K Cho, Vincent Tu, Anthony J Young, Tiffany Dominguez, Justin D Northrup, Jean M Etersque, Hsiaoju S Lee, Andrew Ruff, Ouniol Aklilu, Kyle Bittinger, Laurel J Glaser, Daniel Dorgan, Denis Hadjiliadis, Rahul M Kohli, Robert H Mach, David A Mankoff, Robert K Doot, Mark A Sellmyer: Imaging sensitive and drug-resistant bacterial infection with [11C]-trimethoprim. The Journal of Clinical Investigation 132(18): e156679, Mar 2023 Notes: doi: 10.1172/JCI156679.
d2 Mankoff DA, Sellmyer MA: PET of Fibroblast-Activation Protein for Breast Cancer Diagnosis and Staging. Radiology 302(1): 48-49, Jan 2022.
103 Mark A Sellmyer, Iris K Lee, David A Mankoff: Building the bridge: molecular imaging biomarkers for 21st century cancer therapies. Journal of Nuclear Medicine 62(12): 1672–6, Dec 2021.
139 Jacome, D. A., Northrup, J. D., Ruff, A. J., Reilly, S. W., Lee, I. K., Blizard, G. S., Sellmyer, M. A.: A Chemical Approach for Programmable Protein Outputs Based on Engineered Cell Interactions. ACS Chem Biol 16(1): 52-57, Jan 2021.
182 Sellmyer Mark A, Richman Sarah A, Lohith Katheryn, Hou Catherine, Weng Chi-Chang, Mach Robert H, O'Connor Roddy S, Milone Michael C, Farwell Michael D: Imaging CAR T Cell Trafficking with eDHFR as a PET Reporter Gene. Molecular therapy : the journal of the American Society of Gene Therapy 28(1): 42-51, Jan 2020.
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