About Us

Our lab aims to develop molecular and cellular solutions to address important challenges in the biomedical sciences and clinical medicine, especially in the areas of imaging and diagnostics. We create small molecules, engineered proteins and cell-based tools that can "light up" and control in vivo biology using principles of chemical and synthetic biology. When possible, our technologies are translated to the clinic using nuclear medicine and molecular imaging techniques. For example, our group recently pioneered the development, preclinical testing, and human application of a new class of positron emission tomography (PET) radiotracers based on the small molecule antibiotic trimethoprim. These molecules have diverse applications in our broad fields of investigation including cancer biology, immunology, and infectious disease. If you have any questions about who we are and what we do, don't hesitate to reach out to us!



  • Congratulations Jean on a successful thesis defense!

    Congratulations to Jean on a successful thesis defense! Jean has been an integral member of the lab and a key contributor to a number of the lab's hallmark projects. We are so excited for all that she will accomplish in her post-doctoral career!

  • Congratulations to Jean, Iris & Nitika on their publications!

    Congratulations to Jean, Iris & Nitika on their recent publications in Molecular Therapy and Nature Communications on the development and application of trimethoprim PROTACS. Read more about their work here and here!