Publications

  1. "Regulation of eDHFR-tagged proteins with trimethoprim PROTACs." Etersque, J.M., Lee, I.K., Sharma, N., Xu, K., Ruff, A., Northrup, J.D., Sarkar, S., Nguyen, T., Lauman, R., Burslem, G.M., Sellmyer, M.A. Nat. Commun., 2023, 14 (7071).
  2. "A genetically encoded protein tag for control and imaging of CAR T cell therapy." Lee, I.K., Sharma N., Noguera-Ortega, E., Liousia, M., Baroja, M.L., Etersque, J.M., Pham, J., Sarkar, S., Carreno, B.M., Linette, G.P., Pure, E., Albelda, S.M., Sellmyer, M.A. Mol. Ther., 2023, 31 (12), 3564-3578.
  3. "A microbiome-dependent gut-brain pathway regulates motivation for exercise." Dohnalova, L., Lundgren, P., Carty, J.R.E., Goldstein, N., Wenski, S.L., Nanudom, P., Thiengmag, S., Huang, K.P., Litichevskiy, L., Descamps, H.C., Chellappa, K., Glassman, A., Kessler, S., Kim, J., Cox, T.O., Dmitrieva-Posocco, O., Wong, A.C., Allman, E.L., Ghosh, S., Sharma, N., Sengupta, K., Cornes, B., Dean, N., Churchill, G.A., Khurana, T.S., Sellmyer, M.A., FitzGerald, G.A., Patterson, A.D., Baur, J.A., Alhadeff, A.L., Helfrich, E.J.N., Levy, M., Betley, J.N., Thaiss, C.A. Nature, 2022, 612 (7941), 739-747.
  4. "Imaging sensitive and drug-resistant infection with [11C]-trimethoprim." Lee, I.K.*, Jacome, D.A.*, Cho, J.K., Tu, V., Young, A.J., Dominguez, T., Northrup, J.D., Etersque, J.M., Lee, H.S., Ruff, A., Aklilu, O., Bittinger, K., Glaser, L.J., Dorgan, D., Hadjiliadis, D., Kohli, R.M., Mach, R.H., Mankoff, D.A., Doot, R.K., Sellmyer, M.A. J. Clin. Invest., 2022, 132 (18), e156679. *Co-first authorship.
    See Highlights: "Imaging infection and inflammation." J. Clin. Invest., 2022, 132 (18), e162885.
  5. "Monitoring Therapeutic Response to Anti-FAP CAR-T Cells Using [18F]AlF-FAPI-074." Lee, I.K., Noguera-Ortega, E., Xiao, Z., Todd, L., Scholler, J., Song, D., Liousia, M., Lohith, K., Xu, K. Edwards, K.J., Farwell, M.D., June, C.H., Albelda, S.M., Pure, E., Sellmyer, M.A. Clin. Cancer. Res., 2022, 28 (24), 5330-5342.
    See Highlights: "A Theranostic Approach for CAR-T Cell Therapy." Clin. Cancer Res., 2022, 28 (24), 5241-5243.
  6. "Using CD69 PET Imaging to Monitor Immunotherapy-Induced Immune Activation." Edwards, K.J., Chang, B., Babazada, H., Lohith, K., Park, D.H., Farwell, M.D., Sellmyer, M.A. Cancer Immunol. Res., 2022, 10 (9), 1084-1094.
  7. "PET of Fibroblast-Activation Protein for Breast Cancer Diagnosis and Staging." Mankoff, D.A., Sellmyer, M.A. Radiology, 2022, 302 (1), 48-49.
  8. "Building the Bridge: Molecular Imaging Biomarkers for 21st Century Cancer Therapies." Sellmyer, M.A.,* Lee, I.K.,* & Mankoff, D.A. (2021). Journal of Nuclear Medicine, 2021, 62 (12), 1672-1676. *Co-first authorship.
  9. "18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Following Chimeric Antigen Receptor T-cell Therapy in Large B-cell Lymphoma." Ruff A., Ballard H.J., Pantel A.R., Namoglu E.C., Hughes M.E., Nasta S.D., Chong E.A., Bagg A., Ruella M., Farwell M.D., Svoboda J., Sellmyer M.A. Mol. Imaging Biol., 2021, 23 (6), 818-826.
  10. "A Chemical Approach for Programmable Protein Outputs Based on Engineered Cell Interactions." Jacome, D.A., Northrup, J.D., Ruff, A.J., Reilly, S.W., Lee, I.K., Blizard, G.S., & Sellmyer, M.A. ACS Chemical Biology, 2021, 16 (1), 52-57. 

(Updated December 10, 2023)

  1. "Radiochemical Approaches to Imaging Bacterial Infections: Intracellular versus Extracellular Targets." Northrup, J.D., Mach, R.H., Sellmyer, M.A. Int. J. Mol. Sci., 2019, 20 (22), 5808.
  2. "Imaging CAR T Cell Trafficking with eDHFR as a PET Reporter Gene", Sellmyer, M.A., Richman, S.A., Lohith, K., Hou, C., Weng, C.-C., Mach, R.H., O’Connor, R.S., Milone, M.C., & Farwell, M.D. Molecular Therapy, 2020, 28 (1), 42–51.
  3. "Molecular imaging of bacterial infections: Overcoming the barriers to clinical translation." Ordonez, A., Sellmyer, M., Gowrishankar, G., Ruiz-Bedoya, C., Tucker, E., Palestro, C., Hammoud, D., and Jain, S. Science Translational Medicine, 2019, 11 (508), eaax8251.
  4. “Inflammation and DNA damage: Probing pathways to cancer and neurodegeneration.” Makvandi, M., Sellmyer, M.A. & Mach, R.H. Drug Discov. Today Technol., 2017, 25, 37–43.           
  5.  "Bacterial infection imaging with [18F]fluoropropyl-trimethoprim." Sellmyer, M.A., Lee, I., Hou, C., Weng, C.-C., Li, S., Lieberman, B.P., Zeng, C., Mankoff, D.A., Mach, R.H. Proc. Natl. Acad. Sci., 2017 114(31): 8372-8377. *Co-corresponding authorship.
    See Highlights: Spotlight. Chem. Res. Toxicol. 30, 1653–1654 (2017).
  6. “Quantitative PET reporter gene imaging with [11C]trimethoprim.” Sellmyer, M.A.,* Lee, I., Hou, C., Lieberman, B.P., Zeng, C., Mankoff, D.A., Mach, R.H.* Molecular Therapy, 2017, 25, 120–126. *Co-corresponding authorship.

  1. “Visualizing cell proximity with genetically encoded bioluminescent reporters." Jones, K.A., Li, D.J., Hui, E,. Sellmyer, M.A., Prescher, J.A. ACS Chemical Biology, 2015, 10 (4), 933-938.
  2. “Visualizing Cellular Interactions with a Generalized Proximity Reporter.” Sellmyer, M.A., Bronsart, L., Imoto, H., Contag, C.H., Wandless T.J., Prescher, J.A. Proc. Natl. Acad. Sci., 2013, 110, 8567-8572.
    See Highlights: "Seeing the Light." Science, 2013, 340, 1143–1143; "Sensors and probes: Imaging when cells get together." Nature Methods, 2013, 10, 608–608.
  3. “Physiologic, Histologic, and Imaging Features of Retained Products of Conception.” Sellmyer, M.A., Desser, T.S., Maturen, K.E., Jeffrey, R.B., Kamaya, A. Radiographics 2013, 33, 781–796.
  4. “Intracellular context affects levels of a chemically dependent destabilizing domain.” Sellmyer, M.A., Chun, L.C., Egeler, E.L., Rakhit, R., Wandless, T.J. PLoS ONE, 2012, 7, e43297.
  5. “Chemical control of FGF-2 release for promoting calvarial healing with adipose stem cells.” Kwan, M.D., * Sellmyer, M.A.,* Quarto, N., Ho, A.M., Wandless, T.J., Longaker, M.T. J. Biol. Chem., 2011, 286, 11307–11313 *Co-first authorship.

  1. “A general method for conditional regulation of protein stability in living animals." Sellmyer, M.A., Thorne, S.H., Banaszynski, L.A., Contag, C.H., Wandless, T.J. CSH Protocols, 2009, doi: 10.1101/pdb.prot5173.
  2. "Chemical control of protein stability and function in living animals." Banaszynski, L.A.,* Sellmyer, M.A.,* Contag, C.H., Wandless, T.J., Thorne, S.H. Nature Medicine, 2008, (14) 10, 1123-1127. *Co-first authorship.
  3. “Engineering Small Molecule Specificity in Nearly Identical Cellular Environments.” Sellmyer, M.A., Stankunas, K., Briesewitz, R., Crabtree, G.R., Wandless, T.J. Biog. Med. Chem. Lett., 2007, 17, 2703-5.
  4. "Polymerization of Diacetylenes by Hydrogen Bond Templated Adlayer Formation," Mosley, D.W., Sellmyer, M.A., Daida, E.J., Jacobson, J.M. Journal of the American Chemical Society, 2003, 125, 10532-33.