Faculty

Shaon Sengupta, MBBS, MPH, FAAP

Assistant Professor of Pediatrics (Neonatology & Newborn Services)

Department: Pediatrics

Graduate Group Affiliations

Contact information

Children's Hospital of Philadelphia
Abramson Research Center
3615 Curie Blvd
Office: 1102C
Lab 1103
Philadelphia, PA 19104

Office: 267-426-6628
Fax: 215-590-4267

Education:
MBBS
All India Institute of Medical Sciences, India (Medicine and Surgery) , 2006.
MPH
Johns Hopkins Bloomberg School of Public Health (Epidemiology and Statistics), 2008.

Links
Twitter website

Permanent link

> Perelman School of Medicine > Faculty > Details

Description of Clinical Expertise

Neonatology, ECMO, NRP

Description of Research Expertise

Circadian biology, Lung inflammation, Neonatal lung injury, Influenza, Lung regeneration, Lung organoids

Selected Publications

Sengupta, Shaon; Lee, Yool; Tao, Jian Qin ; Akolia, Isha ; Louneva, Natalia; Forrest, Kaitlyn; Paul, Oindrila; Brooks, Thomas; Grant, Gregory; Sehgal, Amita; Chatterjee, Shampa: Circadian Control of Pulmonary Endothelial Signaling occurs via NADPH oxidase 2-NLRP3 pathway. Under review at Journal of Biological Rhythms. Page: doi: https://doi.org/10.1101/2022.06.05.493624, May 2025 Notes: On Bioarchives since 2022, now under review at JBR.

KM Forrest, M Towers, O Paul, H Cho, M.V. Padmini, A Naik, HK Lim, Y Issah, H.S Deshmukh, M.C. Abt, KM Hudock, GR. Grant, TG. Brooks, S Sengupta: Role of IL10 signaling in the circadian control of host response to Influenza infection bioRxiv 2025.03.03.641134; doi: https://doi.org/10.1101/2025.03.03.641134 March 2025 Notes: Under review at JCI.

Sengupta S, Smith DF, Koritala BSC. : Circadian Rhythms, Immune Regulation, and the Risk for Sepsis: Circadian Rhythms and Neonatal Care. doi: 10.1016/j.clp.2024.10.012. Epub 2024 Nov 26. PMID: 39892952; PMCID: PMC11788575. Clin Perinatol. 52(1): 185-197. March 2025.

O Paul, TG. Brooks, L Assi, A Shetty, M Towers, KM Forrest, A Cameron, A Sehgal, GR. Grant, S Sengupta: Effect of external cues on clock-driven protection from Influenza A infection bioRxiv 2025.03.03.641279; doi: https://doi.org/10.1101/2025.03.03.641279 March 2025.

Brooks TG, Lahens NF, Mrčela A, Yang J, Purohit S, Naik A, Ricciotti E, Sengupta S, Choi PS, Grant GR. : Sources of non-uniform coverage in short-read RNA-Seq data. bioRxiv [Preprint]. 6:2025.01.30.634337. doi: 10.1101/2025.01.30.634337. Feb 2025.

Joseph Stevens, Erica Culberson, Jeremy Kinder, Alicia Ramiriqui, Jerilyn Gray, Madeline Bonfield, Tzu-Yu Shao, Faris Al Gharabieh, Laura Peterson, Shelby Steinmeyer, William Zacharias, Gloria Pryhuber, Oindrila Paul, Shaon Sengupta, Theresa Alenghat, Sing Sing Way, Hitesh Deshmukh: Microbiota-derived inosine programs protective CD8+ T cell responses against influenza in newborns In press, Cell 2025 Notes: Accepted in March 2025, undergoing editorial processing at Cell.

Thomas Brooks , Nicholas Lahens , Antonijo Mrčela , Dimitra Sarantopoulou , Soumyashant Nayak , Amruta Naik , Shaon Sengupta , Peter Choi, G.R. Grant: BEERS2: RNA-Seq simulation through high fidelity in silico modeling. Briefings in Bioinformatics 2024.

Naik A, Forrest K, Paul O, Issah Y, Valekunja UK, Tang SY, Reddy AB, Hennessy E, Brooks TS, Chaudhry F, Babu A, Morley M, Zepp JA, Grant GR, FitzGerald GA, Sehgal A, Worthen GS, Frank DB, Morrisey EE, Sengupta S.: Circadian regulation of lung repair and regeneration JCI Insight Page: e164720. doi: 10.1172/jci.insight.164720. August 2023.

Cox SL, O’Siorain JR, He Y, Lordan R, Naik A, Tang SY, Sengupta S, FitzGerald GA, Carroll RG, Curtis AM.: Circadian disruption in lung fibroblasts enhances NF-κB activity to exacerbate neutrophil recruitment. FASEB J 37(2): e22753 Feb 2023.

Christopher M. Cielo, Janet Lioy, Darko Stefanovski, Shaon Sengupta,, Sagori Mukhopadhyay, Mary Anne Cornaglia, Ignacio E. Tapia: Respiratory indices during sleep in healthy infants: a prospective longitudinal study and metanalysis Sleep Medicine 99(1): 49-57, Nov 2022.