Shaon Sengupta, MBBS, MPH, FAAP

faculty photo
Assistant Professor of Pediatrics
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
Abramson Research Center
3615 Curie Blvd
Office: 1102C
Lab 1103
Philadelphia, PA 19104
Office: 267-426-6628
Fax: 215-590-4267
All India Institute of Medical Sciences, India (Medicine and Surgery) , 2006.
Johns Hopkins Bloomberg School of Public Health (Epidemiology and Statistics), 2008.
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Description of Clinical Expertise

Neonatology, ECMO, NRP

Description of Research Expertise

Circadian biology, Lung inflammation, Neonatal lung injury, Influenza, Lung regeneration, Lung organoids

Selected Publications

Cox SL, O’Siorain JR, He Y, Lordan R, Naik A, Tang SY, Sengupta S, FitzGerald GA, Carroll RG, Curtis AM.: Circadian disruption in lung fibroblasts enhances NF-κB activity to exacerbate neutrophil recruitment. FASEB J 37(2): e22753 Feb 2023.

Naik A, Forrest K, Issah Y, Valekunja UK, Reddy AB, Hennessy E, Brooks TS, Babu A, Morley M, Grant GR, FitzGerald GA, Sehgal A, Worthen GS, Frank DB, Morrisey EE, Sengupta S.: Circadian regulation of lung repair and regeneration JCI Insight- Accepted May 2023 Earlier version in: bioRxiv 2021.11.20.469376; doi: https://doi.org/10.1101/2021.11.20.469376 2023.

Thomas Brooks , Nicholas Lahens , Antonijo Mrčela , Dimitra Sarantopoulou , Soumyashant Nayak , Amruta Naik , Shaon Sengupta , Peter Choi, G.R. Grant: BEERS2: RNA-Seq simulation through high fidelity in silico modeling. Pending 2023.

Christopher M. Cielo, Janet Lioy, Darko Stefanovski, Shaon Sengupta,, Sagori Mukhopadhyay, Mary Anne Cornaglia, Ignacio E. Tapia: Respiratory indices during sleep in healthy infants: a prospective longitudinal study and metanalysis Sleep Medicine 99(1): 49-57, Nov 2022.

S Sengupta, Y Lee, J Q Tao, A Sehgal and S Chatterjee: Circadian Control of Pulmonary Endothelial Signaling occurs via NADPH oxidase 2-NLRP3 pathway. Bioarchives Page: doi: https://doi.org/10.1101/2022.06.05.493624, June 2022 Notes: online pub.

Theken KN, Tang SY, Sengupta S, FitzGerald GA.2021 : The roles of lipids in SARS-CoV-2 viral replication and the host immune response. J Lipid Res. 62(100129): doi: 10.1016/j.jlr.2021.100129, Sep 2021.

Felt SA, Sun Y, Jozwik A, Paras A, Habibi MS, Nickle D, Anderson L, Achouri E, Feemster KA, Cárdenas AM, Turi KN, Chang M, Hartert TV, Sengupta S, Chiu C, López CB: Detection of respiratory syncytial virus defective genomes in nasal secretions is associated with distinct clinical outcomes. Nature Microbiology 6(5): 672-681, May 2021.

Issah Y, Naik A, Tang SY, Forrest K, Brooks TG, Lahens N, Theken KN, Mermigos M, Sehgal A, Worthen GS, FitzGerald GA, Sengupta S: Loss of circadian Protection against Influenza Infection in Adult mice Exposed to Hyperoxia as neonates. eLife (eds.). 2(10): e61241, March 2021.

Sengupta S, Ince L, Sartor F, Borrmann H, Zhuang X, Naik A, Curtis AM, McKeating JA: Clocks, Viruses, and Immunity: Lessons for the COVID-19 Pandemic. Journal Of Biological Rhythms 36(1): 23-34, February 2021.

Sengupta S, Brooks TG, Grant GR, FitzGerald GA: Accounting for Time: Circadian Rhythms in the Time of COVID-19. J Biol Rhythms 36(1): 4-8, Sep 2020.

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Last updated: 05/22/2023
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