Thomas H. Leung, M.D., Ph.D.
Assistant Professor of Dermatology
Department: Dermatology
Graduate Group Affiliations
Contact information
421 Curie Boulevard
Philadelphia, PA 19104
Philadelphia, PA 19104
Education:
B.S. (Biological Sciences)
Stanford University, Stanford, CA, 1998.
Ph.D. (Biology)
California Institute of Technology, Pasadena, CA, 2005.
M.D. (Medicine)
UCLA School of Medicine, Los Angeles, CA, 2007.
Permanent linkB.S. (Biological Sciences)
Stanford University, Stanford, CA, 1998.
Ph.D. (Biology)
California Institute of Technology, Pasadena, CA, 2005.
M.D. (Medicine)
UCLA School of Medicine, Los Angeles, CA, 2007.
Selected Publications
Siprashvili Z, Nguyen NT, Gorell ES, Loutit K, Khuu P, Furukawa LK, Lorenz HP, Leung TH, Keene DR, Rieger KE, Khavari P, Lane AT, Tang JY, Marinkovich MP: Safety and Wound Outcomes Following Genetically Corrected Autologous Epidermal Grafts in Patients With Recessive Dystrophic Epidermolysis Bullosa. JAMA 316(17): 1808, 2016.Leung TH, Snyder ER, Liu Y, Wang J, Kim SK: A cellular, molecular, and pharmacological basis for appendage regeneration in mice. Genes Dev 29(20): 2097-107, 2015.
Gorrell, E.S., Leung, T.H., Khuu, P., Lane, A.T.: Purified Type I collagen wound matrix improves chronic wound healing in patients with recessive dystrophic epidermolysis bullosa. Pediatr Dermatol. 32(2): 220-5, 2014.
Sebastiano, V., Zhen, H.H., Derafshi, B.H., Bashkirova, E., Melo, S., Wang, P., Leung, T.L., Siprashvili, Z., Tichy, A., Li, J., Ameen, M., Hawkins, J., Lee, S., Li, L., Schwertschkow, A., Bauer, G., Lisowski, L., Kay, M.A., Kim, S.K., Lane, A.T., Wernig, M., Oro, A.E.: Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa. Science Translational Medicine 26;6(264):264ra163, 2014.
Danial, C., Tichy, A.L., Tariq, U., Swetman, G.L., Khuu, P., Leung, T.H., Benjamin, L., Teng, J, Vasanawala, S.S., Lane, A.T.: An open-label study to evaluate sildenafil for the treatment of lymphatic malformations. J Am Acad Dermatol S0190-9622(14)01119-0, 2014.
Leung, T.H., Zhang, L.F., Wang, J., Ning, S., Knox, S.J., Kim, S.K. : Topical hypochlorite ameliorates NF-κB-mediated skin diseases in mice. The Journal of Clinical Investigation 123(12): 5361-70, 2013.
Covert, M.W., Leung, T.H., Gaston, J.E., Baltimore, D. : Achieving stability of LPS-induced NF-kB activation. Science 309(5742): 1854-7, 2005. Notes: *These authors contributed equally to this work.
Leung, T.H., Hoffmann, A., Baltimore, D.: One nucleotide change in a kappa B site can determine cofactor specificity for NF-kB dimers. Cell 118(4): 453-64, 2004.
Hoffmann, A., Leung, T.H., Baltimore, D.: Genetic analysis of NF-kappaB/Rel transcription factors defines functional specificities. EMBO J 22(20): 5530-9, 2003.