Faculty

Thomas H. Leung, M.D., Ph.D.

Assistant Professor of Dermatology

Department: Dermatology

Graduate Group Affiliations

Contact information

421 Curie Boulevard
1001 Biomedical Research Building II/III, Room 1006
Philadelphia, PA 19104

Email:
thl@pennmedicine.upenn.edu

Education:
B.S. (Biological Sciences)
Stanford University, Stanford, CA, 1998.
Ph.D. (Biology)
California Institute of Technology, Pasadena, CA, 2005.
M.D. (Medicine)
UCLA School of Medicine, Los Angeles, CA, 2007.

Links
Thomas Leung Lab

Permanent link

> Perelman School of Medicine > Faculty > Details

Selected Publications

Sati S., Jones P., Kim H.S., Zhou L.A., Rapp-Reyes E., and Leung T.H. : HiCuT: An efficient and low input method to identify protein-directed chromatin interactions. PLoS Genet. 18(3): e1010121, Mar 23 2022 Notes: doi: 10.1371/journal.pgen.1010121. Online ahead of print.

Leung T.H. and Cotsarelis G.: Cellular Memories – More Than Skin Deep N Eng J Med 386(8): 793-795, Feb 2022 Notes: In press.

Peraramelli S., Zhou Q., Zhou Q., Wanko B., Zhao L., Nishimura T., Leung T.H., Mizuno S., Ito M., Myles T., Stulnig T.M., Morser J., and Leung L.L. : Thrombin cleavage of osteopontin initiates osteopontin’s tumor-promoting activity. J Thomb Haemost Feb 2 2022 Notes: doi: 10.1111/jth.15663. Online ahead of print.

Brennan-Crispi D.M., Frankfurter M., Murphy C., Sheng E., Xu M., Morrisey E.E., Millar S.E.*, and Leung T.H.* : FZD2 Regulates Murine Hair Follicle Function and Maintenance. J Invest Dermatol. S0022-202X(22): 00011-2, Jan 17 2022 Notes: *These authors contributed equally to this work. Online ahead of print.

Wei J.J., Kim H.S., Spencer C.A., Brennan-Crispi D., Zheng Y., Johnson N.M., Rosenbach M., Miller C., Leung, D.H., Cotsarelis G., and Leung T.H. : Activation of TRPA1 Nociceptor Promotes Systemic Adult Mammalian Skin Regeneration. Science Immunology 5(50), 2020.

Nishiguchi M.A., Spencer C.A., Leung D.H., and Leung T.H. : Aging suppresses skin-derived circulating SDF1 to promote full-thickness tissue regeneration. Cell Reports 24(13): 3383-3392, Oct 2018.

Siprashvili Z, Nguyen NT, Gorell ES, Loutit K, Khuu P, Furukawa LK, Lorenz HP, Leung TH, Keene DR, Rieger KE, Khavari P, Lane AT, Tang JY, Marinkovich MP: Safety and Wound Outcomes Following Genetically Corrected Autologous Epidermal Grafts in Patients With Recessive Dystrophic Epidermolysis Bullosa. JAMA 316(17): 1808, 2016.

Leung TH, Snyder ER, Liu Y, Wang J, Kim SK: A cellular, molecular, and pharmacological basis for appendage regeneration in mice. Genes Dev 29(20): 2097-107, 2015.

Gorrell, E.S., Leung, T.H., Khuu, P., Lane, A.T.: Purified Type I collagen wound matrix improves chronic wound healing in patients with recessive dystrophic epidermolysis bullosa. Pediatr Dermatol 32(2): 220-5, 2014.

Danial, C., Tichy, A.L., Tariq, U., Swetman, G.L., Khuu, P., Leung, T.H., Benjamin, L., Teng, J, Vasanawala, S.S., Lane, A.T.: An open-label study to evaluate sildenafil for the treatment of lymphatic malformations. J Am Acad Dermatol S0190-9622(14)01119-0, 2014.