Gui-shuang Ying, MD, PhD

faculty photo
Associate Professor of Ophthalmology at the Hospital of the University of Pennsylvania
Department: Ophthalmology
Graduate Group Affiliations

Contact information
3711 Market Street, Suite 801
Philadelphia, PA 19104
MD (Preventive Medicine)
Zhejiang Medical University, 1993.
MPH (Toxicology)
Zhejiang Medical University, 1996.
MS (Biostatistics)
University of Michigan-Ann Arbor, 2000.
PhD (Biostatistics)
University of Pennsylvania, 2004.
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Description of Research Expertise

Dr. Ying is an Associate Professor of Ophthalmology, Associate Scholar in Biostatistics, and Director of the Biostatistical Consulting Service in the Center for Preventive Ophthalmology and Biostatistics. Dr. Ying received his MD from P.R. China and Ph.D. in Biostatistics from University of Pennsylvania in 2004. Dr. Ying is the Principal Investigator or the Director of the Data Coordinating Center for several NIH-funded studies on retinopathy of prematurity (ROP), age-related macular degeneration, and the co-investigator or senior biostatistician for several NIH-funded multi-center clinical trials or observational studies. Dr. Ying collaborates with investigators for the study design, data management, statistical analysis, data interpretation and manuscript writing for the multi-center clinical studies. Dr. Ying has extensive experience in collaborating with ophthalmologists and vision researchers on conducting clinical studies for eye diseases. Dr. Ying lead his statistical team for proving biostatistical consulting service to the biomedical investigators, mostly in vision and ophthalmology community. Dr. Ying’s statistical methodologic research interest is the development of risk prediction models for eye diseases and statistical analysis for correlated data. Dr. Ying has authored and co-authored 247 papers in peer-reviewer journals.

Key words
Biostatistics consulting, prediction model, correlated data analysis

Selected Publications

Ying GS, Dobson V, Quinn G, Maguire M, Kulp MT, Cyert L and Vision in Preschoolers (VIP) Study Group: Impact of Confidence Number on the Accuracy of SureSight Vision Screener. Optom Vis Sci 87: 96-103, 2010.

Simonelli F, Maguire AM, Testa F ,Pierce EA, Mingozzi F, Bennicelli J, Rossi S, Marshall K, Banfi S, Surace EM, Sun J, Redmond M, Zhu X, Shindler KS, Ying GS, Ziviello C, Acerra C, Wright JF, DcDonnel JW, High KA, Bennett J, Auricchio A: Gene therapy for Leber’s congenital amaurosis is safe and effective through 1.5 years after vector administration. Molecular Therapy 18: 643-50, 2010.

Maguire AM, High KA, Auriccho A, Wright JF, Pierce EA, Testa F, Mingozzi F, Bennicelli J, Ying GS, Rossi S, Marshall KA, Banfi S, Chung D, Morgan JA, Hauck B, Zelanaia O, Zhu X, Raffini L, Coppieters F, Elfride DB, Schindler K, Volpe N, Surace EM, Acerra C, Lyubarsky A, Redmond TM, Stone E, Sun J, McDonnell JW, Leroy BP, Simonelli F, Bennett J: Phase I gene therapy shows reversal of congenital blindness: Age-dependent effect of treatment. Lancet 374: 1597-605, 2009.

Ying GS, Maguire MG, Alexander J, Martin R, Antoszyk A: Description of the AREDS 9-step severity scale applied to participants in CAPT. Archives of Ophthalmology 127: 1147-51, 2009.

Maguire MG, Ying GS, McCannel C, Liu CC, Dai Y: Statin use and the incidence of advanced age-related macular degeneration in the Complications of Age-related Macular Degeneration Prevention Trial (CAPT). Ophthalmology 116: 2381-5, 2009.

Ying GS, Maguire MG, Liu C, Antoszyk AN, and the CAPT Research Group: Night Vision Symptoms and Progression of Age-Related Macular Degeneration in the Complications of Age-related macular degeneration Prevention Trial. Ophthalmology 115(11): 1876-1882, 2008.

Ying GS, Heitjan DF: Weibull Prediction of Event Times in Randomized Clinical Trials. Pharmaceutical Statistics 7: 107-120, 2008.

Ying GS, Heitjan DF, Chen T: Nonparametric prediction of event times in randomized clinical trials. Clinical Trials 1: 352-61, 2004.

Schenk M, Schwartz AG, O’Neal E, Kinnard M, Greenson JK, Fryzek JP, Ying GS, Garabrant DH: Familial risk of pancreas cancer. J Natl Cancer Inst 93: 640-4, 2001.

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Last updated: 08/20/2019
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