Daniel H. Wolf, M.D., Ph.D.

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Associate Professor of Psychiatry
Department: Psychiatry
Graduate Group Affiliations

Contact information
Richards Building, Room A506
University of Pennsylvania
3700 Hamilton Walk
Philadelphia, PA 19104
Office: 215-662-3692
Fax: 215-662-7903
A.B. (Biology)
Harvard College, 1992.
Ph.D. (Neuroscience)
Yale University School of Medicine, 2000.
M.D. (Medicine)
Yale University School of Medicine, 2001.
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Description of Research Expertise

Key Words
psychosis, reward, motivation, negative symptoms, fMRI, pharmacological imaging

Research interests, techniques, and summary:
My overarching goal is to develop a translational research program to study the neural mechanisms of reward and motivation deficits in psychosis, depression, addiction, and other psychiatric disorders, and in those at risk for these disorders. By utilizing pharmacological challenges during functional neuroimaging, together with detailed clinical and behavioral assessments, I seek to relate these deficits to dysfunction in specific neural circuits, and develop better methods for assessing novel therapeutic interventions. I am also developing active collaborations with geneticists, animal researchers, and pharmaceutical industry scientists in order facilitate clinical translation of basic neuroscientific discoveries.
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Last updated: 09/01/2023
The Trustees of the University of Pennsylvania