Brian Litt, MD

faculty photo
Perelman Professor of Neurology
Department: Neurology
Graduate Group Affiliations

Contact information
Hospital: HUP
3 West Gates / 4283
34th Spruce Street

Lab: 301 Hayden Hall
3320 Smith Walk
Philadelphia, PA 19104
Office: (215) 746-4850
Fax: (215)-349-5733
Harvard University Cum Laude, Engineering and Applied Sciences, 1982.
M.D. ( )
Johns Hopkins University School of Medicine, 1986.
Permanent link

Description of Research Expertise

Epilepsy, EEG, Clinical Neurophysiology, Epilepsy Surgery, Brain Stimulation, Implantable devices, network neuroscience, deep brain stimulation, functional imaging, neuroengineering, Biomedical engineering, computational neuroscience.

Selected Publications

Lucas A, Campbell Arnold T, Okar SV, Vadali C, Kawatra KD, Ren Z, Cao Q, Shinohara RT, Schindler MK, Davis KA, Litt B, Reich DS, Stein JM.: Multi-contrast high-field quality image synthesis for portable low-field MRI using generative adversarial networks and paired data. Radiology in revision, May 2024.

Gallagher RS, Sinha N, Pattnaik AR, Ojemann WKS, Lucas A, LaRocque JJ, Bernabei JM, Greenblatt AS, Sweeney EM, Chen HI, Davis KA, Conrad EC, Litt B.: Quantifying interictal intracranial EEG to predict focal epilepsy. Brain Communications in press, May 2024.

Xie K, Ojemann WKS, Gallagher RS, Lucas A, Hill CE, Hamilton RH, Johnson KB, Roth D, Litt B, Ellis CA.: Disparities in seizure outcomes revealed by large language models. Journal Am Med Inform Assoc. 13(ocae047), March 2024 Notes: doi: 10.1093/jamia/ocae047.

Lucas A, Scheid BH, Pattnaik AR, Gallagher R, Mojena M, Tranquille A, Prager B, Gleichgerrcht E, Gong R, Litt B, Davis KA, Das S, Stein JM, Sinha N.: iEEG-recon: A Fast and Scalable Pipeline for Accurate Reconstruction of Intracranial Electrodes and Implantable Devices. Epilepsia Dec 2023.

Emmert BE, Xie K, Conrad EC, Ghosn NJ, Bauman K, Korzun J, Kulick-Soper CV, Naveed O, Hartmann N, LaRocque JJ, Mindy Ganguly T, Gugger JJ, Raghupathi R, Gelfand MA, Davis KA, Sinha SR, Litt B, Shinohara RT, Ellis CA.: Alcohol for seizure induction in the epilepsy monitoring unit. Epilepsy Behav 150: 109572, Dec 2023.

Knight A, Gschwind T, Galer P, Worrell GA, Litt B, Soltesz I, Beniczky S.: Artificial Intelligence in Epilepsy Phenotyping. Epilepsia Nov 2023.

Xie K, Terman SW, Gallagher RS, Hill CE, Davis KA, Litt B, Roth D, Ellis CA.: Generalization of finetuned transformer language models to new clinical contexts. JAMIA Open 6: ooad070, Aug 2023.

Pattnaik AR, Ghosn NJ, Ong IZ, Revell AY, Ojemann WKS, Scheid BH, Georgostathi G, Bernabei JM, Conrad EC, Sinha SR, Davis KA, Sinha N, Litt B.: The seizure severity score: a quantitative tool for comparing seizures and their response to therapy. J Neural Eng 20, Aug 2023.

Decker BM, Ellis CA, Schriver E, Fischbein K, Smith D, Moyer JT, Kulick-Soper CV, Mowery D, Litt B, Hill CE.: Characterizing the treatment gap in the United States among adult patients with a new diagnosis of epilepsy. Epilepsia 64(7): 1862-1872, Jul 2023.

Ojemann WKS, Scheid BH, Mouchtaris S, Lucas A, LaRocque JJ, Aguila C, Ashourvan A, Caciagli L, Davis KA, Conrad EC, Litt B.: Resting-state background features demonstrate multidien cycles in long-term EEG device recordings. Brain Stimul Jul 2023.

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Last updated: 04/19/2024
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